Results 121 to 130 of about 210,454 (234)

Heterogeneity of the gut microbiome in mice : guidelines for optimizing experimental design [PDF]

open access: yes, 2015
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human ...
Brinkman, Brigitta   +4 more
core   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Effect of Predators of Juvenile Rodents on the Spread of the Hantavirus Epidemic [PDF]

open access: yesarXiv, 2005
Effects of predators of juvenile mice on the spread of the Hantavirus are analyzed in the context of a recently proposed model. Two critical values of the predation probability are identified. When the smaller of them is exceeded, the hantavirus infection vanishes without extinguishing the mice population.
arxiv  

Copy number variants and selective sweeps in natural populations of the house mouse (Mus musculus domesticus) [PDF]

open access: yes, 2014
Copy–number variants (CNVs) may play an important role in early adaptations, potentially facilitating rapid divergence of populations. We describe an approach to study this question by investigating CNVs present in natural populations of mice in the ...
Axelsson   +35 more
core   +2 more sources

Mitochondrial haplotype and sex modulate responses to endurance exercise training

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn   +8 more
wiley   +1 more source

Differential Levels of Glutamate Dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 Mice and the Effects of Overexpression of the Gene on Glutamate Release in Striatum

open access: yesASN Neuro, 2011
We have previously shown that overexpression of the Glud1 (glutamate dehydrogenase 1) gene in neurons of C57BL/6 mice results in increased depolarization-induced glutamate release that eventually leads to selective neuronal injury and cell loss by 12 ...
Kevin N Hascup   +9 more
doaj   +1 more source

Progress of the MICE experiment [PDF]

open access: yesarXiv, 2015
The international Muon Ionization Cooling Experiment (MICE) will perform a systematic investigation of ionization cooling of a muon beam. The demonstration is based on a simplified version of a neutrino factory cooling channel. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation has been ...
arxiv  

Radiation-induced myeloid leukemia in murine models. [PDF]

open access: yes, 2014
The use of radiation therapy is a cornerstone of modern cancer treatment. The number of patients that undergo radiation as a part of their therapy regimen is only increasing every year, but this does not come without cost.
Davoren, Michael   +2 more
core   +2 more sources

Genetic analysis of cholesterol accumulation in inbred mice

open access: yesJournal of Lipid Research, 2001
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz   +3 more
doaj  

Early hippocampal high-amplitude rhythmic spikes predict post-traumatic epilepsy in mice

open access: yesFrontiers in Neuroscience
Oscillations, a highly conserved brain function across mammalian species, play a pivotal role in both brain physiology and pathology. Traumatic brain injury (TBI) frequently results in subacute and chronic alterations in brain oscillations, which are ...
Tyler Shannon   +15 more
doaj   +1 more source

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