Results 131 to 140 of about 329,438 (265)

Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]

, 2004
Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K., Ellenberger, E. A., Mueller, Janet L., Quock, Raymond M., Vaughn, Linda K.   +4 more
core   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

The Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin, Andrea Carrer, Federica Boscolo Nata, Elena Frigo, Federico Fogolari, Giovanna Lippe, Michela Carraro, Paolo Bernardi   +7 more
wiley   +1 more source

Copy number variants and selective sweeps in natural populations of the house mouse (Mus musculus domesticus) [PDF]

, 2014
Copy–number variants (CNVs) may play an important role in early adaptations, potentially facilitating rapid divergence of populations. We describe an approach to study this question by investigating CNVs present in natural populations of mice in the ...
Axelsson, Bryk, Carter, Cooper, Cucchi, Cutler, Didion, Dieringer, Egan, Ellegren, Faircloth, Fare, Feuk, Gentleman, Gonzalez, Graubert, Hastings, Henrichsen, Ihle, Karolchik, Lee, Perry, Pozhitkov, Redon, Rozen, Schlötterer, Schlötterer, Staubach, Stranger, Teschke, Wang, Wang, Williams, Wineinger, Yalcin, Yang   +35 more
core   +2 more sources

Genetic Background Influences Adaptation To Cardiac Hypertrophy and Ca2+ Handling Gene Expression

Frontiers in Physiology, 2013
Genetic variability has a profound effect on the development of cardiac hypertrophy in response to stress. Consequently, using a variety of inbred mouse strains with known genetic profiles may be powerful models for studying the response to ...
Steve B Waters, Doug eDiak, Matthew eZuckerman, Lara eLeoni, Paul Harvey Goldspink, Brian B Roman   +5 more
doaj   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

The role of Sp140 revealed in IgE and mast cell responses in Collaborative Cross mice

JCI Insight, 2021
Mouse IgE and mast cell (MC) functions have been studied primarily using inbred strains. Here, we (a) identified effects of genetic background on mouse IgE and MC phenotypes, (b) defined the suitability of various strains for studying IgE and MC ...
Kazufumi Matsushita, Xin Li, Yuki Nakamura, Danyue Dong, Kaori Mukai, Mindy Tsai, Stephen B. Montgomery, Stephen J. Galli   +7 more
doaj   +1 more source

Metabolomics and Microbiomics Perspectives Reveal the Regulatory Pathways of Monaphilone B Derived From Red Yeast Rice on Alcoholic Liver Injury in Mice

eFood, Volume 6, Issue 2, April 2025.
Monaphilone B (MB) from red yeast rice mitigates alcoholic liver injury through the regulation of the gut microbiome, liver metabolism, lipid metabolism, and oxidative defense. ABSTRACT Red yeast rice (RYR) has been extensively used as a natural food for thousands of years and still plays an important role in the world food industry. In this study, the
Li Wu, Zihua Liang, Ziyi Yang, Hao Wang, Li Ni, Weiling Guo, Xucong Lv   +6 more
wiley   +1 more source

In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. [PDF]

, 2019
Early life exposure to fine particulate matter (PM) in air is associated with infant respiratory disease and childhood asthma, but limited epidemiological data exist concerning the impacts of ultrafine particles (UFPs) on the etiology of childhood ...
Chang, Richard C-A, Golding, Michael C, Johnson, Natalie M, Langley, Rebecca, Lau, Carmen, Leal, Jeann, Li, Yixin, Molina, Mario J, Myatt, Louise G, Pulczinski, Jairus, Raju, Muppala, Rodrigues-Hoffmann, Aline, Rychlik, Kristal A, Secrest, Jeremiah R, Zamora, Misti L, Zhang, Renyi   +15 more
core  

A Proposed New Nomenclature for the Immunoglobulin Genes of Mus musculus

Frontiers in Immunology, 2019
Mammalian immunoglobulin (IG) genes are found in complex loci that contain hundreds of highly similar pseudogenes, functional genes and repetitive elements, which has made their investigation particularly challenging.
Christian E. Busse, Katherine J. L. Jackson, Corey T. Watson, Andrew M. Collins   +3 more
doaj   +1 more source

Diversity in the radiation-induced transcriptomic temporal response of mouse brain tissue regions [PDF]

arXiv
A number of studies have indicated a potential association between prenatal exposure to radiation and late mental disabilities. This is believed to be due to long-term developmental changes and functional impairment of the central nervous system following radiation exposure during gestation.
arxiv