Results 131 to 140 of about 350,782 (186)

Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice.

Carcinogenesis, 1986
Treatment of newborn male C3H/HeJ mice with N,N-diethyl-nitrosamine (DEN) or N-ethyl-N-nitrosourea (ENU) resulted in the induction of hepatocellular adenomas and carcinomas with a mean number of tumors per animal that was approximately 20- to 50-fold higher than that for similarly treated C57BL/6J male mice.
N. Drinkwater, J. Ginsler
semanticscholar   +3 more sources

Ethanol Teratogenesis in Selectively Bred Long‐Sleep and Short‐Sleep Mice: A Comparison to Inbred C57BL/6J Mice

Alcoholism: Clinical and Experimental Research, 1989
Sensitivity to alcohol may influence the severity of ethanol teratogenesis. To examine this hypothesis, the teratogenic effects of ethanol were compared in Long‐Sleep (LS) and Short‐Sleep (SS) mice, selectively bred for differences in ethanol‐induced narcosis.
D. Gilliam, L. Kotch, B. Dudek, E. Riley
semanticscholar   +3 more sources

Behavioural and neuroanatomical divergence between two sublines of C57BL/6J inbred mice

Behavioural Brain Research, 1991
Male mice of strains C57BL/6J and DBA/2J differ reproducibly in a number of behaviours displayed in an open-field. In particular, C57BL/6J mice show a higher rearing-up frequency than do DBA/2J animals. Recently, a marked drop occurred in the frequency with which this behaviour is displayed by the C57BL/6J//Nmg (N) subline, that has been separated from
Wim E Crusio   +2 more
semanticscholar   +3 more sources

Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice

Mammalian Genome, 1999
Genetic analyses for loci regulating bone mineral density have been conducted in a cohort of F(2) mice derived from intercross matings of (C57BL/6J x CAST/EiJ)F(1) parents. Femurs were isolated from 714 4-month-old females when peak adult bone density had been achieved.
W. Beamer   +6 more
semanticscholar   +3 more sources

Behavioral sensitization to drug stimulant effects in C57BL/6J and DBA/2J inbred mice.

Behavioral Neuroscience, 1994
Common features shared by addictive drugs have been difficult to identify. One ubiquitous effect of these drugs is psychomotor stimulation. Further, repeated exposure commonly results in sensitization to drug stimulant effects. This study evaluates sensitization to drugs from several drug classes in C57BL/6J and DBA/2J inbred strain mice.
Tamara J. Phillips   +2 more
semanticscholar   +3 more sources

A behavioral and neuroanatomical assessment of an inbred substrain of 129 mice with behavioral comparisons to C57BL/6J mice

Brain Research, 1999
The inbred 129 substrains have been characterized as poor learners that display hypoplasia of the corpus callosum. However, they are used extensively as a source of embryonic stem (ES) cells for creating mice carrying altered copies of a targeted gene ('knockout mice'). The present research investigated callosal agenesis and behavior in the 129/SvEvTac
S. Balogh   +3 more
semanticscholar   +3 more sources

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