Results 1 to 10 of about 6,402 (64)

Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]

, 2015
Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO, PUGLISI ALLEGRA, Stefano, VENTURA, Rossella   +2 more
core   +1 more source

Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]

, 2015
Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO, Maran, Dario, PUGLISI ALLEGRA, Stefano, Viscomi, Maria Teresa   +3 more
core   +1 more source

Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. [PDF]

, 2016
We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting.
Avetisyan, Rozeta, Gong, Ke Wei, Lusis, Aldons J, Rau, Christoph, Ren, Shuxun, Romay, Milagros C, Stolin, Gabriel, Wang, Jessica Jen-Chu, Wang, Yibin   +8 more
core   +7 more sources

Lifespan modulation in mice and the confounding effects of genetic background [PDF]

, 2014
We are currently in the midst of a revolution in ageing research, with several dietary, genetic and pharmacological interventions now known to modulate ageing in model organisms.
Mulvey, Lorna, Selman, Colin, Sinclair, Amy   +2 more
core   +1 more source

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
A Ghazalpour, A Reverter, A Subramanian, AJ Butte, BA Taylor, BE Stranger, BH Voy, C Wu, Chris J. Cotsapas, CJ Cotsapas, D Gatti, D Vlieghe, David J. Nott, E Petretto, EJ Chesler, EJ Chesler, EJ Foss, Eva K. F. Chan, G Gibson, G Passador-Gurgel, HH Goring, I Hovatta, I Lönnstedt, J Brumm, JC Gower, Jeremy N. Pulvers, JJ Keurentjes, JJ Nadler, KA Frazer, L Bystrykh, M Bansal, M Mehrabian, M Wirth, MA West, Mark J. Cowley, MC Frith, Michael Y. Liu, MP Keller, MT Pletcher, MV Rockman, N Hubner, NN Batada, Oscar J. Luo, P Blache, Peter F. R. Little, R Ihaka, R Sandberg, RB Brem, RB Williams, RC Gentleman, RM Kuhn, Rohan B. H. Williams, S Biswas, TC Freeman, TM Fruchterman, V Emilsson, X Yang, Y Chen, Y Fukuoka   +58 more
core   +4 more sources

Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]

, 2004
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S., Simon, Michelle, Kumar, Saumya, Fernandes, Vitor E., Sylvius, Nicolas, Mallon, Ann-Marie, Denny, Paul, Andrew, Peter W.   +7 more
core   +5 more sources

Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]

, 1993
Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E., Kanagawa, Osami, Osman, Gamal-E, Toda, Masaaki   +3 more
core   +2 more sources

Co-Housing Rodents with Different Coat Colours as a Simple, Non-Invasive Means of Individual Identification:Validating Mixed-Strain Housing for C57BL/6 and DBA/2 Mice [PDF]

, 2013
Standard practice typically requires the marking of laboratory mice so that they can be individually identified. However, many of the common methods compromise the welfare of the individuals being marked (as well as requiring time, effort, and/or ...
A Ennaceur, A Santoso, BC Jones, C Touma, C Touma, Carole Fureix, CC Burn, CL Howerton, CM Nevison, CM Nevison, CZ Cannon, DB Sorensen, DC Schaefer, E Choleris, ED Berglund, ES Orwoll, F Dellu, G Griebel, Georgia Mason, GJ Mason, GJ Sanger, H Harizi, IAS Olsson, IHE Kasanen, J Podhorna, J Vaahtovuo, JA Newman, JC Gonder, JL Hurst, JP Curley, JP Garner, JS Han, K Brennan, K Dahlborn, K Priebe, KG Brand, LE Elcock, MD Walker, Michael Walker, MJ Castelhano-Carlos, MK Meijer, P Cinelli, P Singer, P Toivanen, P Willner, PV Guillot, R Adamec, R Palme, R Trullas, R Urban, RMJ Deacon, Rupert Palme, S Cabib, S Iwaki, S Le Calvez, S Pothion, SH Hurlbert, SH Richter, SLC Tilly, SP Kelley, SS Moy, T Tillmann, TC Goes, TS Perlstein, Wim E. Crusio, WJ Sheward, WO Williams, Y Winter   +67 more
core   +6 more sources

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior [PDF]

, 2015
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Borevitz, Justin O., Distler, Margaret G., Harr, Bettina, Lim, Jackie E., Palmer, Abraham A., Sokoloff, Greta, Su, Andrew I., Tarantino, Lisa M., Teschke, Meike, Walters, Ryan, Williams, Richard, Wiltshire, Tim, Wing, Claudia, Wu, Chunlei   +13 more
core   +2 more sources

Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]

, 1975
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan, Boyum, Brunner, Calder, Cohen, Epstein, Evans, Fulginiti, Gardner, Gardner, Glasgow, Good, Hecht, Janossy, Julius, Koszinowski, Labowskie, Lohmann-Mathes, Lundstedt, Marker, McFarland, Oldstone, Perlmann, Perlmann, Profitt, Schirrmacher, Shearer, Shortman, Speel, Steele, Ueda, Ueda, Von Pirquet, Wagner, Wagner, Zinkernagel, Zinkernagel   +36 more
core   +1 more source