Results 11 to 20 of about 1,160,575 (212)
Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity [PDF]
Background Recent discoveries suggest that arealization of the mammalian cortical sheet develops in a manner consonant with principles established for embryonic patterning of the body.
Wu Fangbai +4 more
doaj +5 more sources
Geometric morphometrics defines shape differences in the cortical area map of C57BL/6J and DBA/2J inbred mice [PDF]
Background We previously described planar areal differences in adult mouse visual, somatosensory, and neocortex that collectively discriminated C57BL/6J and DBA/2J inbred strain identity.
Guan Monica +3 more
doaj +3 more sources
In previous studies, we have demonstrated that mice of the inbred strain C57BL/6J (C57) are more susceptible to amphetamine-induced conditioned place preference (CPP) than DBA/2J (DBA) mice. Moreover, we also observed parallel strain differences for the locomotor-stimulant effects of the drug.
ORSINI, CRISTINA +3 more
openaire +3 more sources
Individual variability in the response to pharmacological therapies is a major problem in the treatment of psychiatric disorders. Comparative studies of phenotypes expressed by mice of the C57BL/6J (C57) and DBA/2J (DBA) inbred strains can help identify neurobiological determinants of this variability at preclinical levels.
Maiolati, Marzia +4 more
openaire +4 more sources
BALB/c mice deficient in CD4(+) T cell IL-4R alpha expression control Leishmania mexicana load although female but not male mice develop a healer phenotype [PDF]
Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4R alpha-deficient mice fail to develop lesions and develop a robust ...
Owain R Millington +29 more
core +4 more sources
Chronobiology of alcohol: Studies in C57BL/6J and DBA/2J inbred mice [PDF]
Human alcoholics display dramatic disruptions of circadian rhythms that may contribute to the maintenance of excessive drinking, thus creating a vicious cycle. While clinical studies cannot establish direct causal mechanisms, recent animal experiments have revealed bidirectional interactions between circadian rhythms and ethanol intake, suggesting that
Alan M, Rosenwasser, Michael C, Fixaris
openaire +2 more sources
Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Koszinowski, Ulrich H. +3 more
core +1 more source
Inter-strain differences of serotonergic inhibitory pain control in inbred mice [PDF]
Background: Descending inhibitory pain control contributes to the endogenous defense against chronic pain and involves noradrenergic and serotonergic systems.
Albuquerque Boris +17 more
core +1 more source
Modulation of aggression in male mice: influence of group size and cage size [PDF]
Aggression in group-housed male mice is known to be influenced by both cage size and group size. However, the interdependency of these two parameters has not been studied yet. In this study, the level of aggression in groups of three, five, or eight male
van Loo, P.L.P. +18 more
core +2 more sources
Major gene effects on traits associated with substance use disorders are rare. Previous findings in methamphetamine drinking (MADR) lines of mice, bred for high or low voluntary MA intake, and in null mutants demonstrate a major impact of the trace amine-
Cheryl Reed +8 more
doaj +1 more source

