Results 21 to 30 of about 13,142 (173)

Effects of isolation housing stress and mouse strain on intravenous cocaine self-administration, sensory stimulus self-administration, and reward preference

Scientific Reports, 2023
Sensory stimuli are natural rewards in mice and humans. Consequently, preference for a drug reward relative to a sensory reward may be an endophenotype of addiction vulnerability.
Michael Leonardo, Sarah Brunty, Jessica Huffman, Deranda B. Lester, Price E. Dickson   +4 more
doaj   +1 more source

Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion

Molecular Metabolism, 2022
Objectives: Glucagon secretion to stimulate hepatic glucose production is the first line of defense against hypoglycemia. This response is triggered by so far incompletely characterized central hypoglycemia-sensing mechanisms, which control autonomous ...
Alexandre Picard, Xavier Berney, Judit Castillo-Armengol, David Tarussio, Maxime Jan, Ana Rodriguez Sanchez-Archidona, Sophie Croizier, Bernard Thorens   +7 more
doaj   +1 more source

GENETIC ANALYSIS OF AUDIOGENIC SEIZURE SUSCEPTIBILITY IN C57BL/6J x DBA/2J RECOMBINANT INBRED STRAINS OF MICE [PDF]

Genetics, 1980
ABSTRACT The inheritance of susceptibility to audiogenic seizures (ASS) was studied in the C57BW6J (B6) and DBA/2j (D2) progenitor strains, their reciprocal F1 hybrids, backcross generations and in 21 B6 × D2 recombinant inbred (RI) strams of mice at 21 days of age.
Seyfried, T N, Yu, R K, Glaser, G H
openaire   +2 more sources

Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea

Laboratory Animal Research, 2018
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam, Yoo Yeon Kim, Boyoung Kim, Won Kee Yoon, Hyoung-Chin Kim, Jun Gyo Suh   +5 more
doaj   +1 more source

Genetic background modulates the phenotype of a mouse model of DYT1 dystonia. [PDF]

PLoS ONE, 2012
DYT1 dystonia is a debilitating neurological disease characterized by involuntary twisting movements. The disease is caused by an in-frame deletion (GAG, "ΔE") mutation in the TOR1A gene that encodes the torsinA protein.
Lauren M Tanabe, Caitlin Martin, William T Dauer   +2 more
doaj   +1 more source

Genetic analysis of cholesterol accumulation in inbred mice

Journal of Lipid Research, 2001
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz, Daphne L. Davis, Bertrand R. Vick, David W. Russell   +3 more
doaj   +1 more source

The adjuvant effect of polymuramil, a NOD1 and NOD2 agonist, differs when immunizing mice of different inbred lines with nonstructural hepatitis C virus (Flaviviridae: Hepacivirus)proteins and is synergistically enhanced in combination with pyrogenalum, a TLR4 agonist

Вопросы вирусологии, 2023
Introduction. Hepatitis C is a liver disease with high chronicity, the cause of cirrhosis and hepatocarcinoma. The main obstacle to controlling hepatitis C is the lack of vaccines.
Ekaterina I. Lesnova, Olga V. Masalova, Kristina Yu. Permyakova, Natalia A. Demidova, Vladimir T. Valuev-Elliston, Alexandr V. Ivanov, Alla A. Kushch   +6 more
doaj   +1 more source

Differences in the Flexibility of Switching Learning Strategies and CREB Phosphorylation Levels in Prefrontal Cortex, Dorsal Striatum, and Hippocampus in Two Inbred Strains of Mice

Frontiers in Behavioral Neuroscience, 2016
Flexibility in using different learning strategies was assessed in two different inbred strains of mice, the C57BL/6 and DBA/2 strains. Mice were trained sequentially in two different Morris water maze protocols that tested their ability to switch their ...
Woo-Hyun Cho, Jung-Soo Han
doaj   +1 more source

THE EFFECTS OF GROUP VERSUS SINGLE HOUSING ON HOME CAGE BEHAVIOUR IN TWO STRAINS OF LABORATORY MICE

Slovenian Veterinary Research, 2019
Studying the behavioural patterns of animals in their house may help to understand their needs, but there has been a little investigation of home-cage behaviours in commonly used inbred strains of mice such as C57BL/6 and DBA/2. Therefore, understanding
Ahmed F. Abou-Elnaga, Ibrahim F. Rehan, Ralph R Thompson, Usama A Abou-Ismail, Motamed E Mahmoud, Radi A Mohamed, Hesham H Mohammed, Ahmed A Sabek, Mohamed Z Elhussiny   +8 more
doaj   +1 more source

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

Neural Plasticity, 2017
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, Il Yong Kim, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon   +7 more
doaj   +1 more source