Results 21 to 30 of about 1,160,575 (212)
Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice, [PDF]
Journal of Lipid Research, 2003 To investigate genetic contributions to individual variations of lipoprotein cholesterol concentrations, we performed quantitative trait locus/loci (QTL) analyses of an intercross of CAST/Ei and DBA/2J inbred mouse strains after feeding a high-cholesterol cholic acid diet for 10 weeks. In total, we identified four QTL for HDL cholesterol.
Lyons, M A +6 more
openaire +2 more sources
Foster dams rear fighters: strain-specific effects of within-strain fostering on aggressive behavior in male mice. [PDF]
PLoS ONE, 2013 It is well known that genes and environment interact to produce behavioral phenotypes. One environmental factor with long-term effects on gene transcription and behavior is maternal care.
Kimberly H Cox +2 more
doaj +1 more source
Virology Journal, 2012 Background The mouse represents an important model system to study the host response to influenza A infections and to evaluate new prevention or treatment strategies. We and others reported that the susceptibility to influenza A virus infections strongly
Dengler Leonie +4 more
doaj +1 more source
Genes, Brain and Behavior, 2023 AbstractNicotine is the reinforcing ingredient in tobacco. Following chronic exposure, sudden cessation of nicotine use produces negative symptoms of withdrawal that contribute to dependence. The molecular mechanisms underlying nicotine withdrawal behaviors, however, are poorly understood.
Maren L. Smith +5 more
openaire +2 more sources
A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23ahl underlie the early onset, age-related hearing loss of DBA/2J mice [PDF]
, 2008 The DBA/2J inbred strain of mice is used extensively in hearing research, yet little is known about the genetic basis for its early onset, progressive hearing loss.
Zheng, Qing Yin +9 more
core +1 more source
Presphenoidal synchondrosis fusion in DBA/2J mice [PDF]
, 2012 Cranial base growth plates are important centers of longitudinal growth in the skull and are responsible for the proper anterior placement of the face and the stimulation of normal cranial vault development. We report that the presphenoidal synchondrosis
Bowen, Margot Elizabeth +11 more
core +1 more source
Scientific Reports, 2023 Sensory stimuli are natural rewards in mice and humans. Consequently, preference for a drug reward relative to a sensory reward may be an endophenotype of addiction vulnerability.
Michael Leonardo +4 more
doaj +1 more source
A Behavioral Comparison of Four Inbred Strains of Mice [PDF]
, 2010 Isogenic, or inbred, mouse strains are currently the experimental subjects of choice in laboratory studies focused on genetics, pharmacology, and psychological issues.
Wood, Erin
core +1 more source
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion
Molecular Metabolism, 2022 Objectives: Glucagon secretion to stimulate hepatic glucose production is the first line of defense against hypoglycemia. This response is triggered by so far incompletely characterized central hypoglycemia-sensing mechanisms, which control autonomous ...
Alexandre Picard +7 more
doaj +1 more source