Results 11 to 20 of about 6,402 (64)
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
Effects of environmental enrichment upon ethanol-induced conditioned place preference and pre-frontal BDNF levels in adolescent and adult mice [PDF]
, 2017 Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs.
Camarini, Rosana +6 more
core +1 more source
Allele-specific expression and eQTL analysis in mouse adipose tissue. [PDF]
, 2014 BackgroundThe simplest definition of cis-eQTLs versus trans, refers to genetic variants that affect expression in an allele specific manner, with implications on underlying mechanism.
Drake, Thomas A +6 more
core +2 more sources
Antitumor effect of lysine-isopeptides [PDF]
, 2002 Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect.
Almás, M +6 more
core +4 more sources
Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
Alcohol, Clinical and Experimental Research, Volume 49, Issue 4, Page 712-724, April 2025.In this narrative review, we identify barriers to the translation of preclinical comorbidity models of alcohol use disorder and depressive disorders, including temporal and pharmacological discrepancies. In humans, depression is high during and immediately after the cessation of drinking and usually remits subsequently, while in animals it seems to ...
Garrett A. Winkler, Nicholas J. Grahame
wiley +1 more source
Radiation-induced myeloid leukemia in murine models. [PDF]
, 2014 The use of radiation therapy is a cornerstone of modern cancer treatment. The number of patients that undergo radiation as a part of their therapy regimen is only increasing every year, but this does not come without cost.
Davoren, Michael +2 more
core +2 more sources
Genes, Brain and Behavior, Volume 24, Issue 2, April 2025.Core symptoms of human DCD modeled in BXD recombinant inbred strains of mice. Significant strain differences for all measures of motor coordination were found. Three significant quantitative trait loci and seven candidate genes for gait were identified.
Jeffy Rajan Soundara Rajan +6 more
wiley +1 more source
Presphenoidal synchondrosis fusion in DBA/2J mice [PDF]
, 2013 Cranial base growth plates are important centers of longitudinal growth in the skull and are responsible for the proper anterior placement of the face and the stimulation of normal cranial vault development. We report that the presphenoidal synchondrosis
Adams, Allysa Claire +5 more
core +1 more source
To Tweak or Not to Tweak. How Exploiting Flexibilities in Gene Set Analysis Leads to Overoptimism
Biometrical Journal, Volume 67, Issue 1, February 2025.ABSTRACT Gene set analysis, a popular approach for analyzing high‐throughput gene expression data, aims to identify sets of genes that show enriched expression patterns between two conditions. In addition to the multitude of methods available for this task, users are typically left with many options when creating the required input and specifying the ...
Milena Wünsch +4 more
wiley +1 more source