Results 31 to 40 of about 48,234 (239)

Predicting Yield Performance of Parents in Plant Breeding: A Neural Collaborative Filtering Approach [PDF]

open access: yesPLoS ONE 15(5): e0233382 (2020), 2020
Experimental corn hybrids are created in plant breeding programs by crossing two parents, so-called inbred and tester, together. Identification of best parent combinations for crossing is challenging since the total number of possible cross combinations of parents is large and it is impractical to test all possible cross combinations due to limited ...
arxiv   +1 more source

Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]

open access: yes, 2015
Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO   +2 more
core   +1 more source

Safety Embedded Differential Dynamic Programming Using Discrete Barrier States [PDF]

open access: yesIEEE ROBOTICS AND AUTOMATION LETTERS, VOL. 7, NO. 2, APRIL 2022, 2021
Certified safe control is a growing challenge in robotics, especially when performance and safety objectives must be concurrently achieved. In this work, we extend the barrier state (BaS) concept, recently proposed for safe stabilization of continuous time systems, to safety embedded trajectory optimization for discrete time systems using discrete ...
arxiv   +1 more source

Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]

open access: yes, 2015
Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO   +3 more
core   +1 more source

Lifespan modulation in mice and the confounding effects of genetic background [PDF]

open access: yes, 2014
We are currently in the midst of a revolution in ageing research, with several dietary, genetic and pharmacological interventions now known to modulate ageing in model organisms.
Mulvey, Lorna   +2 more
core   +1 more source

Species differences in comorbid alcohol use disorder and major depressive disorder: A narrative review. [PDF]

open access: yesAlcohol Clin Exp Res (Hoboken)
In this narrative review, we identify barriers to the translation of preclinical comorbidity models of alcohol use disorder and depressive disorders, including temporal and pharmacological discrepancies. In humans, depression is high during and immediately after the cessation of drinking and usually remits subsequently, while in animals it seems to ...
Winkler GA, Grahame NJ.
europepmc   +2 more sources

Intra- and inter-individual genetic differences in gene expression [PDF]

open access: yes, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
A Ghazalpour   +58 more
core   +4 more sources

Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]

open access: yes, 2004
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S.   +7 more
core   +5 more sources

Empirical likelihood for estimating equations with missing values [PDF]

open access: yesAnnals of Statistics 2009, Vol. 37, No. 1, 490-517, 2009
We consider an empirical likelihood inference for parameters defined by general estimating equations when some components of the random observations are subject to missingness. As the nature of the estimating equations is wide-ranging, we propose a nonparametric imputation of the missing values from a kernel estimator of the conditional distribution of
arxiv   +1 more source

Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice, [PDF]

open access: yesJournal of Lipid Research, 2003
To investigate genetic contributions to individual variations of lipoprotein cholesterol concentrations, we performed quantitative trait locus/loci (QTL) analyses of an intercross of CAST/Ei and DBA/2J inbred mouse strains after feeding a high-cholesterol cholic acid diet for 10 weeks. In total, we identified four QTL for HDL cholesterol.
Lyons, M A   +6 more
openaire   +3 more sources

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