Results 41 to 50 of about 19,573 (206)

THE EFFECTS OF GROUP VERSUS SINGLE HOUSING ON HOME CAGE BEHAVIOUR IN TWO STRAINS OF LABORATORY MICE

Slovenian Veterinary Research, 2019
Studying the behavioural patterns of animals in their house may help to understand their needs, but there has been a little investigation of home-cage behaviours in commonly used inbred strains of mice such as C57BL/6 and DBA/2. Therefore, understanding
Ahmed F. Abou-Elnaga, Ibrahim F. Rehan, Ralph R Thompson, Usama A Abou-Ismail, Motamed E Mahmoud, Radi A Mohamed, Hesham H Mohammed, Ahmed A Sabek, Mohamed Z Elhussiny   +8 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

Age-related thymic involution in C57BL/6J × DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10 [PDF]

Genes & Immunity, 2003
A comprehensive analysis of initial thymus size and involution rate has not been quantitated for different genetic backgrounds of mice, thus genetic linkage analysis of thymic involution has not been possible. Here, we have used a mathematical method to analyze the age-related decline in thymocyte count in C57BL/6 and DBA/2 mice and have observed that ...
H-C, Hsu, H-G, Zhang, L, Li, N, Yi, P-A, Yang, Q, Wu, J, Zhou, S, Sun, X, Xu, X, Yang, L, Lu, G, Van Zant, R W, Williams, D B, Allison, J D, Mountz   +14 more
openaire   +2 more sources

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

Neural Plasticity, 2017
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, Il Yong Kim, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon   +7 more
doaj   +1 more source

Enhancement of Leishmania amazonensis infection in BCG non-responder mice by BCG-antigen specific vaccine

Memorias do Instituto Oswaldo Cruz, 1992
Different patterns of cutaneous leishmaniasis can be induced when a challenge of alike dose of Leishmania amazonensis amastigotes in various inbred strains was applied.
Kátia da Silva Calabrese, Sylvio Celso Gonçalves da Costa   +1 more
doaj   +1 more source

Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping [PDF]

, 2007
Immobility in the tail suspension test (TST) is considered a model of despair in a stressful situation, and acute treatment with antidepressants reduces immobility. Inbred strains of mouse exhibit widely differing baseline levels of immobility in the TST
Fernandes, C, Lad, H V, Liu, L, Paya-Cano, J L, Schalkwyk, L C   +4 more
core   +2 more sources

Confirmation of multiple seizure susceptibility QTLs on chromosome 15 in C57BL/6J and DBA/2J inbred mice

Physiological Genomics, 2010
To confirm seizure susceptibility (SZS) quantitative trait loci (QTLs) on chromosome (chr) 15 identified previously using C57BL/6J (B6) and DBA/2J (D2) mice and to refine their genomic map position, we studied a set of three congenic strains in which overlapping segments of chr 15 from D2 were transferred onto the B6 background.
T N, Ferraro, G G, Smith, C L, Schwebel, G A, Doyle, S E, Ruiz, J U, Oleynick, F W, Lohoff, W H, Berrettini, R J, Buono   +8 more
openaire   +3 more sources

Insufficient generation of mycobactericidal mediators and inadequate level of phagosomal maturation are related with susceptibility to virulent Mycobacterium tuberculosis infection in mouse macrophages

Frontiers in Microbiology, 2016
Tuberculosis is caused by Mycobacterium tuberculosis (M. tuberculosis, Mtb) infection, and it remains major life-threatening infectious diseases worldwide. Although Mtb has infected one-third of the present human population, only 5-10% of immunocompetent
Hyo-Ji eLee, Hyun-Jeong eKo, Yu-Jin eJung   +2 more
doaj   +1 more source

Differences between NMRI and DBA/2J mice in the development of somites and susceptibility to methylnitrosourea-induced skeleton anomalies [PDF]

, 2017
The development of DBA/2J mouse strain embryos is nearly 12 h - or 6 somite pairs - delayed as compared to the outbred NMRI mouse embryos of the same age on gestation days (GD) 8-12.
Chahoud, Ibrahim, Paumgarttem, Francisco J. R.   +1 more
core   +1 more source

A Meta‐Analysis of the Effects of Chronic Stress on the Prefrontal Transcriptome in Animal Models and Convergence With Existing Human Data

Brain and Behavior, Volume 16, Issue 1, January 2026.
Chronic stress is linked to many human psychiatric disorders involving the prefrontal cortex (PFC). We performed a meta‐analysis of public transcriptional profiling data that showed that chronically stressed mice have less gene expression for glia and neural activity in the PFC. These findings mirror patterns seen in psychiatric patients.
Jinglin Xiong, Megan H. Hagenauer, Cosette A. Rhoads, Elizabeth Flandreau, Nancy Rempel‐Clower, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Toni Duan, Stanley Watson Jr., Huda Akil   +10 more
wiley   +1 more source