Results 61 to 70 of about 13,850 (186)

Helminth Parasites of Conventionally Maintained Laboratory Mice: II- Inbred Strains with an Adaptation of the Anal Swab Technique

Memorias do Instituto Oswaldo Cruz, 1998
Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves, Roberto Magalhães Pinto, J Júlio Vicente, Dely Noronha, Delir Corrêa Gomes   +4 more
doaj   +1 more source

Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]

PLoS ONE, 2014
The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen, Hongbo Zhang, Zhou Zhou, Zhangsheng Yang, Yiling Ding, Zhiguang Zhou, Edward Zhong, Bernard Arulanandam, Joel Baseman, Guangming Zhong   +9 more
doaj   +1 more source

Genetically humanized phenylketonuria mouse model as a testing tool for human genome editing in fertilized eggs

Journal of Inherited Metabolic Disease, Volume 48, Issue 1, January 2025.
Abstract Targeted genome editing has made significant advancements; however, safety and ethical issues have not been fully elucidated, resulting in strict control of the technique. We tested genome editing tools on gametes from a genetically humanized mouse model using a phenylketonuria (PKU) mouse model to gain insights into genome editing in human ...
Atsumi Tsuji‐Hosokawa, Iku Tsuchiya, Kie Shimizu, Miho Terao, Mito Yasuhara, Natsuho Miyamoto, Saki Kikuchi, Yuya Ogawa, Kazuaki Nakamura, Yoichi Matsubara, Shuji Takada   +10 more
wiley   +1 more source

Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning

Frontiers in Genetics, 2020
Type 2 diabetes (T2D) is a complex metabolic disease regulated by an interaction of genetic predisposition and environmental factors. To understand the genetic contribution in the development of diabetes, mice varying in their disease susceptibility were
Heja Aga, Heja Aga, Nicole Hallahan, Nicole Hallahan, Pascal Gottmann, Pascal Gottmann, Markus Jaehnert, Markus Jaehnert, Sophie Osburg, Sophie Osburg, Gunnar Schulze, Gunnar Schulze, Anne Kamitz, Anne Kamitz, Danny Arends, Gudrun Brockmann, Tanja Schallschmidt, Tanja Schallschmidt, Sandra Lebek, Sandra Lebek, Alexandra Chadt, Alexandra Chadt, Hadi Al-Hasani, Hadi Al-Hasani, Hans-Georg Joost, Hans-Georg Joost, Annette Schürmann, Annette Schürmann, Annette Schürmann, Heike Vogel, Heike Vogel, Heike Vogel   +31 more
doaj   +1 more source

Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men. [PDF]

PLoS ONE, 2014
The objective of our study was to identify genetic factors that regulate bone mineral density (BMD) in mice using well defined recombinant inbred strains. For this purpose we chose the BXD recombinant inbred (RI) strains derived from progeny of the C57BL/
Lishi Wang, Wenli Lu, Lei Zhang, Yue Huang, Rachel Scheib, Xiaoyun Liu, Linda Myers, Lu Lu, Charles R Farber, Gaifen Liu, Cong-Yi Wang, Hongwen Deng, Robert W Williams, Yongjun Wang, Weikuan Gu, Yan Jiao   +15 more
doaj   +1 more source

Why an integrated view of gene expression studies on hematopoiesis in mouse aging is better than the sum of their parts

FEBS Letters, Volume 598, Issue 22, Page 2765-2773, November 2024.
A standard approach to studying aging in mice typically involves the isolation of hematopoietic stem cells from two cohorts, namely young and old, from which total RNA is extracted, sequenced, and analyzed through R‐based standard protocols. The lists of differentially expressed genes resulting from these analyses are usually interpreted with Gene ...
Leonid V. Bystrykh
wiley   +1 more source

Alcohol and fear conditioning produce strain‐specific changes in the dorsal hippocampal transcriptome of adolescent C57BL/6J and DBA/2J mice

Alcohol, Clinical and Experimental Research, Volume 48, Issue 11, Page 2022-2034, November 2024.
Adolescent sensitivity to alcohol is influenced by sex and genetics. We utilized RNA‐sequencing to identify transcriptional changes associated with fear learning deficits after alcohol exposure in male and female adolescent mice from two unique inbred strains. We identified networks that likely contributed to learning differences after alcohol exposure,
Laurel R. Seemiller, Lisa R. Goldberg, Aswathy Sebastian, Sue Rutherford Siegel, Craig Praul, Dana Zeid, Istvan Albert, Jacob Beierle, Camron D. Bryant, Thomas J. Gould   +9 more
wiley   +1 more source

Delayed and transient increase of adult hippocampal neurogenesis by physical exercise in DBA/2 mice.

PLoS ONE, 2013
This study builds on the findings that physical activity, such as wheel running in mice, enhances cell proliferation and neurogenesis in the adult hippocampus of the common mouse strain C57BL/6, and that the baseline level of neurogenesis varies by ...
Rupert W Overall, Tara L Walker, Odette Leiter, Sina Lenke, Susann Ruhwald, Gerd Kempermann   +5 more
doaj   +1 more source

On the Spectral Evolution of Helium-Atmosphere White Dwarfs Showing Traces of Hydrogen [PDF]

, 2018
We present a detailed spectroscopic analysis of 115 helium-line (DB) and 28 cool, He-rich hydrogen-line (DA) white dwarfs based on atmosphere fits to optical spectroscopy and photometry. We find that 63% of our DB population show hydrogen lines, making them DBA stars.
arxiv   +1 more source

Mouse development - From oocyte to stem cells

European Journal of Histochemistry, 2014
This is a really good book for those who love developmental biology: young fellows at the beginning of their careers, esteemed professors, historians of science or fully active leading researchers.
Manuela Monti
doaj   +1 more source