Results 71 to 80 of about 13,850 (186)

Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains. [PDF]

PLoS ONE, 2011
The mouse has emerged as a uniquely valuable species for studying the molecular and genetic basis of complex behaviors and modeling neuropsychiatric disease states.
Lauren Lederle, Susanna Weber, Tara Wright, Michael Feyder, Jonathan L Brigman, Hans S Crombag, Lisa M Saksida, Timothy J Bussey, Andrew Holmes   +8 more
doaj   +1 more source

Reactions to spatial and nonspatial change in two inbred strains of mice: Further evidence supporting the hippocampal dysfunction hypothesis in the DBA/2 strain [PDF]

Psychobiology, 1995
Mice belonging to the inbred C57BL/6 and DBA/2 strains were repeatedly exposed to a given spatial configuration of five objects contained in an open field. Locomotor activity, habituation of exploration, and reactivity to the displacement of some objects (spatial change) and to the substitution of a familiar object by a new one (nonspatial change) were
Ammassari Teul M, Tozzi, Alessandro, Rossi Arnaud C, Save E, Thinus Blanc C.   +4 more
openaire   +4 more sources

Working with Miraculous Mice: Mus musculus as a Model Organism

Current Protocols, Volume 4, Issue 10, October 2024.
Abstract The laboratory mouse has been described as a “miracle” model organism, providing a window by which we may gain an understanding of ourselves. Since the first recorded mouse experiment in 1664, the mouse has become the most used animal model in biomedical research.
Anick Standley, Jinhan Xie, Angelica WY Lau, Lauren Grote, Andrew J. Gifford   +4 more
wiley   +1 more source

In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain

Scientific Reports, 2017
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima, Yuji Komaki, Fumiko Seki, Yasuyuki Ohnishi, Hirotaka J. Okano, Hideyuki Okano   +5 more
doaj   +1 more source

Glucose Homeostasis and Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred Strains of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1 [PDF]

Endocrinology, 2004
Abstract Transgenic mice phenotypes generally depend on the background strains used in their creation. To examine the effects of genetic background on insulin signaling, we analyzed glucose homeostasis in four inbred strains of mice [C57BL/6 (B6), C57BLKS/6 (KLS), DBA/2 (DBA), and 129X1] and quantitated mRNA content of insulin receptor ...
H. Joseph Goren, C. Ronald Kahn, Rohit N. Kulkarni   +2 more
openaire   +2 more sources

An automated sleep staging tool based on simple statistical features of mice electroencephalography (EEG) and electromyography (EMG) data

European Journal of Neuroscience, Volume 60, Issue 7, Page 5467-5486, October 2024.
By identifying three simple statistical features that can represent sleep–wake stages in a 3D space, we developed a classification process that aligns with traditional definitions and the intuition of experts. Abstract Electroencephalogram (EEG) and electromyogram (EMG) are fundamental tools in sleep research.
Rikuhiro G. Yamada, Kyoko Matsuzawa, Koji L. Ode, Hiroki R. Ueda   +3 more
wiley   +1 more source

Photon counting spectroscopic CT with dynamic beam attenuator [PDF]

arXiv, 2016
Purpose: Photon counting (PC) computed tomography (CT) can provide material selective CT imaging at lowest patient dose but it suffers from suboptimal count rate. A dynamic beam attenuator (DBA) can help with count rate by modulating x-ray beam intensity such that the low attenuating areas of the patient receive lower exposure, and detector behind ...
arxiv  

Respiratory performance in Duchenne muscular dystrophy: Clinical manifestations and lessons from animal models

Experimental Physiology, Volume 109, Issue 9, Page 1426-1445, 1 September 2024.
Abstract Duchenne muscular dystrophy (DMD) is a fatal genetic neuromuscular disease. Lack of dystrophin in skeletal muscles leads to intrinsic weakness, injury, subsequent degeneration and fibrosis, decreasing contractile function. Dystropathology eventually presents in all inspiratory and expiratory muscles of breathing, severely curtailing their ...
Rebecca Delaney, Ken D. O'Halloran
wiley   +1 more source

Protecting oracle pl/sql source code from a dba user [PDF]

International Journal of Database Management Systems, 4, (2012) 43-52, 2012
In this paper we are presenting a new way to disable DDL statements on some specific PL/SQL procedures to a dba user in the Oracle database. Nowadays dba users have access to a lot of data and source code even if they do not have legal permissions to see or modify them.
arxiv  

Mixed housing with DBA/2 mice induces stress in C57BL/6 mice: implications for interventions based on social enrichment

Frontiers in Behavioral Neuroscience, 2014
Several behavioral interventions, based on social enrichment and observational learning are applied in treatment of neuropsychiatric disorders. However, the mechanism of such modulatory effect and the safety of applied methods on individuals involved in ...
Natalia eKulesskaya, Nina N Karpova, Li eMa, Li eTian, Vootele eVoikar   +4 more
doaj   +1 more source