Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak+4 more
wiley +1 more source
Genetic analysis of cholesterol accumulation in inbred mice
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz+3 more
doaj
Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men. [PDF]
The objective of our study was to identify genetic factors that regulate bone mineral density (BMD) in mice using well defined recombinant inbred strains. For this purpose we chose the BXD recombinant inbred (RI) strains derived from progeny of the C57BL/
Lishi Wang+15 more
doaj +1 more source
The MICE Muon Beam on ISIS and the beam-line instrumentation of the Muon Ionization Cooling Experiment [PDF]
The international Muon Ionization Cooling Experiment (MICE), which is under construction at the Rutherford Appleton Laboratory (RAL), will demonstrate the principle of ionization cooling as a technique for the reduction of the phase-space volume occupied by a muon beam.
arxiv +1 more source
Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice. [PDF]
Background: P. aeruginosa is one of the top three causes of opportunistic human bacterial infections. The remarkable variability in the clinical outcomes of this infection is thought to be associated with genetic predisposition.
A Bragonzi+62 more
core +1 more source
A study of some aspects of growth and reproduction in two inbred lines of mice and their crosses : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Massey University of Manawatu [PDF]
The mating of closely related individuals is generally believed to result in inferior offspring. Recognition of this danger has been suggested as the reason for evolution of human social customs.
Lawson, R A S
core
Maternal Effects on Mouse Brain Weight [PDF]
When BALB/cCF mice were crossed reciprocally with 4 other inbred strains, adult brain weights averaged 21.0 mg heavier for hybrid offspring with a BALB mother than those with a BALB father.
NC DOCKS at The University of North Carolina at Greensboro+1 more
core +1 more source
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza+4 more
wiley +1 more source
Responses to a high fat, high sucrose (HFHS) diet vary greatly among inbred strains of mice. We sought to examine the epigenetic (DNA methylation) changes underlying these differences as well as variation in weight loss when switched to a low-fat chow ...
Chantle R. Edillor+5 more
doaj +1 more source
Modeling the Genetic Basis of Individual Differences in Susceptibility to Gulf War Illness
Between 25% and 30% of the nearly one million military personnel who participated in the 1991 Persian Gulf War became ill with chronic symptoms ranging from gastrointestinal to nervous system dysfunction.
Byron C. Jones+10 more
doaj +1 more source