Results 101 to 110 of about 145,801 (250)

Sexual Abnormalities in an Inbred Strain of Mice

Experimental Biology and Medicine, 1938
An interesting sexual abnormality was observed in the Little-Murray dilute brown strain of mice. To date this abnormality has been observed in 10 animals, and is evidently hereditary. All the abnormal individuals were descendants of the same pair of mice, the ancestors of which were inbred by brother to sister matings for many generations.
openaire   +2 more sources

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

Exploration, EarlyView.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang, Ailan Xu, Lin Guan, Yong Tang, Guangshuai Chai, Junya Feng, Yueqi Wu, Maochen Li, Chuxie Zhang, Xiaojing Liu, Xiaolong Xu, Qingquan Liu, Lihua Song, Yigang Tong, Renald Blundell, Huahao Fan   +15 more
wiley   +1 more source

Joint estimation of genetic and parent-of-origin effects using RNA-seq data from human [PDF]

arXiv, 2017
RNA sequencing allows one to study allelic imbalance of gene expression, which may be due to genetic factors or genomic imprinting. It is desirable to model both genetic and parent-of-origin effects simultaneously to avoid confounding and to improve the power to detect either effect. In a study of experimental cross, separation of genetic and parent-of-
arxiv  

Anatomic correlates of strial presbycusis in recombinant inbred mouse strains [PDF]

, 2010
This project attempts to identify anatomic features that predict the range of the ‘normal’ endocochlear potential in young inbred mice. Cochlear lateral wall histologic metrics were compared in recombinant inbred (RI) mouse strains formed from BALB/c and
Walkonis, Christina M
core   +1 more source

Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena. [PDF]

, 2013
Adult male mice emit large number of complex ultrasonic vocalizations (USVs) when interacting with adult females. Call numbers and call categories differ greatly among inbred mouse strains.
Crawley, Jacqueline N, Kalikhman, David, Loureiro, Darren, Yang, Mu   +3 more
core   +2 more sources

MHC Restriction of V-V Interactions in Serum IgG [PDF]

arXiv, 2014
According to Jerne's idiotypic network hypothesis, the adaptive immune system is regulated by interactions between the variable regions of antibodies, B cells, and T cells.1 The symmetrical immune network theory2,3 is based on Jerne's hypothesis, and provides a basis for understanding many of the phenomena of adaptive immunity.
arxiv  

Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]

, 2009
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R, Bradley, Allan, Liang, Qi, Lloyd, Kent C, Moran, Jennifer L, Pettitt, Stephen J, Prosser, Haydn M, Rairdan, Xin Y, Skarnes, William C   +8 more
core   +1 more source

Stress of Strains: Inbred Mice in Liver Research

Gene Expression, 2019
Inbred mice are the most popular animals used for in vivo liver research. These mice are genetically defined, readily available, less expensive to maintain than larger animals, and enjoy a broad array of commercial reagents for scientific characterization. C57BL/6 mice are the most commonly used strain. However, other strains discussed, including BALB/
openaire   +3 more sources

Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]

, 2004
Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K., Ellenberger, E. A., Mueller, Janet L., Quock, Raymond M., Vaughn, Linda K.   +4 more
core   +1 more source

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
A Ghazalpour, A Reverter, A Subramanian, AJ Butte, BA Taylor, BE Stranger, BH Voy, C Wu, Chris J. Cotsapas, CJ Cotsapas, D Gatti, D Vlieghe, David J. Nott, E Petretto, EJ Chesler, EJ Chesler, EJ Foss, Eva K. F. Chan, G Gibson, G Passador-Gurgel, HH Goring, I Hovatta, I Lönnstedt, J Brumm, JC Gower, Jeremy N. Pulvers, JJ Keurentjes, JJ Nadler, KA Frazer, L Bystrykh, M Bansal, M Mehrabian, M Wirth, MA West, Mark J. Cowley, MC Frith, Michael Y. Liu, MP Keller, MT Pletcher, MV Rockman, N Hubner, NN Batada, Oscar J. Luo, P Blache, Peter F. R. Little, R Ihaka, R Sandberg, RB Brem, RB Williams, RC Gentleman, RM Kuhn, Rohan B. H. Williams, S Biswas, TC Freeman, TM Fruchterman, V Emilsson, X Yang, Y Chen, Y Fukuoka   +58 more
core   +4 more sources