The genetic architecture of NAFLD among inbred strains of mice
eLife, 2015 To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique inbred mouse strains, which were fed a diet
Simon T Hui +14 more
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A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]
PLoS ONE, 2009 Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams +13 more
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Cocaine locomotor activation, sensitization and place preference in six inbred strains of mice
Behavioral and Brain Functions, 2011 Background The expanding set of genomics tools available for inbred mouse strains has renewed interest in phenotyping larger sets of strains. The present study aims to explore phenotypic variability among six commonly-used inbred mouse strains to both ...
Grabowski-Boase Laura +2 more
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Of faeces and sweat. How much a mouse is willing to run: having a hard time measuring spontaneous physical activity in different mouse sub-strains [PDF]
European Journal of Translational Myology, 2017 Physical activity has multiple beneficial effects in the physiology and pathology of the organism. In particular, we and other groups have shown that running counteracts cancer cachexia in both humans and rodents.
Dario Coletti +2 more
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Strain-specific differences in cerulein-induced acute and recurrent acute murine pancreatitis [PDF]
Scientific ReportsHyperstimulation with the secretagogue cerulein is a commonly used experimental model to study acute, recurrent acute and chronic pancreatitis in mice.
Alexandra Demcsák +3 more
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Antibody production in inbred strains of mice.
The Journal of Immunology, 1953 Based on tests involving the use of 5 inbred strains of mice, evidence is presented which indicates that there is genetic variation in the ability of the mouse to produce demonstrable circulating antibody to either egg albumin or pneumococcus ...
M. A. Fink, V. Quinn
semanticscholar +3 more sources
Ethanol teratogenesis in five inbred strains of mice. [PDF]
Alcoholism: Clinical and Experimental Research, 2009 BACKGROUND Previous studies have demonstrated individual differences in susceptibility to the detrimental effects of prenatal ethanol exposure. Many factors, including genetic differences, have been shown to play a role in susceptibility and resistance ...
C. Downing +4 more
semanticscholar +4 more sources
Effects of housing density in five inbred strains of mice. [PDF]
PLoS ONE, 2014 To evaluate the effect of increased mouse density in a cage, mice were housed at the density recommended by the 1996 Guide for the Care and Use of Laboratory Animals and at densities that were approximately 2, 2.6, and 3 times greater.
Judith L Morgan +8 more
doaj +6 more sources
In silico candidate variant and gene identification using inbred mouse strains [PDF]
PeerJ, 2021 Mice are the most widely used animal model to study genotype to phenotype relationships. Inbred mice are genetically identical, which eliminates genetic heterogeneity and makes them particularly useful for genetic studies.
Matthias Munz +4 more
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Scientific Reports, 2023 Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli +11 more
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