Results 21 to 30 of about 106,274 (236)

Sperm morphology in two house mouse subspecies: do wild-derived strains and wild mice tell the same story? [PDF]

PLoS ONE, 2014
Being subject to intense post-copulatory selection, sperm size is a principal determining component of male fitness. Although previous studies have presented comparative sperm size data at higher taxonomic levels, information on the evolution of sperm ...
Jana Albrechtová, Tomáš Albrecht, Ludovít Ďureje, Vincent A Pallazola, Jaroslav Piálek   +4 more
doaj   +1 more source

Rift Valley Fever Virus Is Lethal in Different Inbred Mouse Strains Independent of Sex

Frontiers in Microbiology, 2020
Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting humans and livestock in Africa and the Arabian Peninsula. The majority of human cases are mild and self-limiting; however, severe cases can result in hepatitis, encephalitis, or hemorrhagic
Haley N. Cartwright, Haley N. Cartwright, Dominique J. Barbeau, Dominique J. Barbeau, Anita K. McElroy, Anita K. McElroy   +5 more
doaj   +1 more source

Analysis of structural variation among inbred mouse strains

BMC Genomics, 2023
Background ‘Long read’ sequencing methods have been used to identify previously uncharacterized structural variants that cause human genetic diseases.
Ahmed Arslan, Zhuoqing Fang, Meiyue Wang, Yalun Tan, Zhuanfen Cheng, Xinyu Chen, Yuan Guan, Laura J. Pisani, Boyoung Yoo, Gill Bejerano, Gary Peltz   +10 more
doaj   +1 more source

Susceptibility Analysis in Several Mouse Strains Reveals Robust T-Cell Responses After Mycoplasma pneumoniae Infection in DBA/2 Mice

Frontiers in Cellular and Infection Microbiology, 2021
Mycoplasma pneumoniae (Mp) is a highly contagious respiratory pathogen responsible for human community-acquired pneumonia. The number of antibiotic-resistant Mp strains is increasing; therefore, to develop novel therapeutics, it is crucial to precisely ...
Shigeyuki Tamiya, Shigeyuki Tamiya, Shigeyuki Tamiya, Eisuke Yoshikawa, Eisuke Yoshikawa, Eisuke Yoshikawa, Koichiro Suzuki, Yasuo Yoshioka, Yasuo Yoshioka, Yasuo Yoshioka, Yasuo Yoshioka, Yasuo Yoshioka   +11 more
doaj   +1 more source

Ethanol Teratogenesis in Five Inbred Strains of Mice [PDF]

Alcoholism: Clinical and Experimental Research, 2009
Background: Previous studies have demonstrated individual differences in susceptibility to the detrimental effects of prenatal ethanol exposure. Many factors, including genetic differences, have been shown to play a role in susceptibility and resistance, but few studies have investigated the range of genetic variation in rodent models.Methods: We ...
Chris, Downing, Christina, Balderrama-Durbin, Hali, Broncucia, David, Gilliam, Thomas E, Johnson   +4 more
openaire   +2 more sources

Inter-strain differences of serotonergic inhibitory pain control in inbred mice [PDF]

, 2010
Background: Descending inhibitory pain control contributes to the endogenous defense against chronic pain and involves noradrenergic and serotonergic systems.
Albuquerque Boris, Irmgard Tegeder, Tegeder Irmgard, Laura Popp, Wijnvoord, Nina, Myrczek, Thekla, Tegeder, Irmgard, Wijnvoord Nina, Popp, Laura, Annett Häussler, Häussler, Annett, Nina Wijnvoord, Myrczek Thekla, Häussler Annett, Popp Laura, Boris Albuquerque, Albuquerque, Boris, Thekla Myrczek   +17 more
core   +1 more source

Inbred mouse strains and genetic stability: a review

Animal, 2011
Inbred mice were essential animal models for scientific research during the 20th century and will contribute decisive results in the current and next centuries.
J. Casellas
doaj   +1 more source

Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]

, 1975
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Koszinowski, Ulrich H., Thomssen, R., Thomssen, R, Koszinowski, U   +3 more
core   +1 more source

Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. [PDF]

, 2004
Investigation of sequence variation in common inbred mouse strains has revealed a segmented pattern in which regions of high and low variant density are intermixed.
Keays, D, A, Jefferson, A, Brady, S, Flint, J, Copley, RR, Volpi, E., Keays, D.A., Jefferson, A., Mott, R, Bhomra, A, Miller, S., Mott, R., Copley, R.R., Flint, Jonathan, Yalcin, B., Yalcin, B, Bhomra, A., Fullerton, J, Flint, J., Fullerton, J., Keays, DA, Copley, R, R, Miller, S, Volpi, E, Brady, S.   +24 more
core   +1 more source

Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria surviva [PDF]

, 2010
The genetic background of a patient determines in part if a person develops a mild form of malaria and recovers, or develops a severe form and dies. We have used a mouse model to detect genes involved in the resistance or susceptibility to Plasmodium ...
Winzeler, E.A., Wiltshire, T., Selina E R Bopp, Waters Andrew P., Andrew P. Waters, Luzader, A., Bopp, S.E.R., Waters, A.P., Steffy Brian M., Henson Kerstin, Winzeler Elizabeth A., Ramachandran, V., Suzuki Oscar, Lindstrom, M., Merle Lindstrom, Lindstrom Merle, Oscar Suzuki, Henson, K., Tim Wiltshire, Suzuki, O., Yingyao Zhou, Janse, C., Selina E. R. Bopp, Elizabeth A Winzeler, Spooner, M., Bopp Selina E. R., Zhou Yingyao, Brian M. Steffy, Kerstin Henson, Zhou, Y.Y., Chris Janse, Steffy, B.M., Janse Chris, Wiltshire Tim, Vandana Ramachandran, Muriel Spooner, Luzader Angelina, Angelina Luzader, Ramachandran Vandana, Spooner Muriel, Elizabeth A. Winzeler, Zhou, Y., Brian M Steffy, Andrew P Waters   +43 more
core   +1 more source