Results 11 to 20 of about 1,877,211 (239)
Differences in Exercise Capacity and Responses to Training in 24 Inbred Mouse Strains
Frontiers in Physiology, 2017 Changes in cardiorespiratory fitness in response to a standardized exercise training protocol differ substantially between individuals. Results from cross-sectional, twin, and family studies indicate genetics contribute to individual differences in both ...
Michael Massett, Seung Kyum Kim
exaly +3 more sources
Susceptibility and transcriptional characteristics of inbred C57BL/6J and outbred ICR mice in CDAHFD-induced MASH models [PDF]
Laboratory Animal ResearchBackground Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive fibrotic liver disease, the underlying mechanisms of which have not been fully elucidated.
Jing Zhou +9 more
doaj +2 more sources
Tympanometry assessment of 61 inbred strains of mice [PDF]
Hearing Research, 2007 Otitis media (OM) accounts for more than 20 million clinic visits in the United States every year. Resistance to antibiotics has hampered current management of the disease. Identification of genetic factors underlying susceptibility to OM is greatly needed in order to develop alternative treatment strategies.
Zheng, Q Y +3 more
openaire +4 more sources
Stress of Strains: Inbred Mice in Liver Research
Gene Expression, 2019 Inbred mice are the most popular animals used for in vivo liver research. These mice are genetically defined, readily available, less expensive to maintain than larger animals, and enjoy a broad array of commercial reagents for scientific characterization. C57BL/6 mice are the most commonly used strain.
Arlin B Rogers
exaly +3 more sources
A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model [PDF]
Advanced ScienceA more complete map of the pattern of genetic variation among inbred mouse strains is essential for characterizing the genetic architecture of the many available mouse genetic models of important biomedical traits.
Wenlong Ren +6 more
doaj +2 more sources
In silico candidate variant and gene identification using inbred mouse strains [PDF]
PeerJ, 2021 Mice are the most widely used animal model to study genotype to phenotype relationships. Inbred mice are genetically identical, which eliminates genetic heterogeneity and makes them particularly useful for genetic studies.
Matthias Munz +4 more
doaj +2 more sources
A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]
PLoS ONE, 2009 Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams +13 more
doaj +1 more source
Scientific Reports, 2023 Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli +11 more
doaj +1 more source
Медицинская иммунология, 2014 . The course of infections caused by intracellular parasitic bacteria Salmonella typhimurium and Chlamidophila pneumoniae was compared for inbred strains of mice with genetically determined susceptibity (I/St) or resistance (A/Sn) to Mycobacterium ...
D. V. Balunets +5 more
doaj +3 more sources
Sperm morphology in two house mouse subspecies: do wild-derived strains and wild mice tell the same story? [PDF]
PLoS ONE, 2014 Being subject to intense post-copulatory selection, sperm size is a principal determining component of male fitness. Although previous studies have presented comparative sperm size data at higher taxonomic levels, information on the evolution of sperm ...
Jana Albrechtová +4 more
doaj +1 more source