Results 11 to 20 of about 133,707 (224)
Mycoplasma pneumoniae (Mp) is a highly contagious respiratory pathogen responsible for human community-acquired pneumonia. The number of antibiotic-resistant Mp strains is increasing; therefore, to develop novel therapeutics, it is crucial to precisely ...
Shigeyuki Tamiya +11 more
doaj +1 more source
Inbred mouse strains and genetic stability: a review
Inbred mice were essential animal models for scientific research during the 20th century and will contribute decisive results in the current and next centuries.
J. Casellas
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Placentophagia in Nonpregnant Nulliparous Mice: A Genetic Investigation [PDF]
The genetic influence on the response of nonpregnant nulliparous mice to foster placenta was investigated. Two highly inbred strains (BALB/cBy and C57BL/6By), their F1 hybrids, a backcross generation, and seven recombinant-inbred strains derived from the
Eleftheriou, Basil E. +1 more
core +1 more source
Ethanol Teratogenesis in Five Inbred Strains of Mice [PDF]
Background: Previous studies have demonstrated individual differences in susceptibility to the detrimental effects of prenatal ethanol exposure. Many factors, including genetic differences, have been shown to play a role in susceptibility and resistance, but few studies have investigated the range of genetic variation in rodent models.Methods: We ...
Chris, Downing +4 more
openaire +2 more sources
Differences in Exercise Capacity and Responses to Training in 24 Inbred Mouse Strains
Changes in cardiorespiratory fitness in response to a standardized exercise training protocol differ substantially between individuals. Results from cross-sectional, twin, and family studies indicate genetics contribute to individual differences in both ...
Joshua J. Avila +2 more
doaj +1 more source
Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S. +7 more
core +5 more sources
Strain-Dependent Vascular Remodeling Phenotypes in Inbred Mice [PDF]
We have recently established a mouse model of arterial remodeling in which flow in the left common carotid artery of FVB mice was interrupted by ligation of the vessel near the carotid bifurcation, resulting in a dramatic reduction of the lumen as a consequence of a reduction in vessel diameter and intimal lesion formation.
K J, Harmon, L L, Couper, V, Lindner
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Genetic analysis of cholesterol accumulation in inbred mice
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz +3 more
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Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]
Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO +2 more
core +1 more source
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam +5 more
doaj +1 more source

