Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]
, 2017 Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho +3 more
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ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis. [PDF]
, 2016 Meta-analysis has become a popular tool for genetic association studies to combine different genetic studies. A key challenge in meta-analysis is heterogeneity, or the differences in effect sizes between studies.
Eskin, Eleazar +5 more
core +6 more sources
QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains [PDF]
, 2009 Peer reviewedPublisher ...
Blizard, David A +6 more
core +3 more sources
Tympanometry assessment of 61 inbred strains of mice [PDF]
Hearing Research, 2007 Otitis media (OM) accounts for more than 20 million clinic visits in the United States every year. Resistance to antibiotics has hampered current management of the disease. Identification of genetic factors underlying susceptibility to OM is greatly needed in order to develop alternative treatment strategies.
Zheng, Q Y +3 more
openaire +3 more sources
Ventilatory Phenotypes among Four Strains of Adult Rats. [PDF]
, 2002 Our purpose in this study was to identify different ventilatory phenotypes among four different strains of rats. We examined 114 rats from three in-house, inbred strains and one outbred strain: Brown Norway (BN;n = 26), Dahl salt-sensitive (n = 24), Fawn-
Dwinell, Melinda R. +4 more
core +2 more sources
Analysis of microsatellite polymorphism in inbred knockout mice. [PDF]
PLoS ONE, 2012 Previously, we found that the genotype of 42 out of 198 mouse microsatellite loci, which are distributed among all chromosomes except the Y chromosome, changed from monomorphism to polymorphism (CMP) in a genetically modified inbred mouse strain. In this
Baofen Zuo +8 more
doaj +1 more source
Genetic regulation of mouse liver metabolite levels. [PDF]
, 2014 We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of 104 inbred and ...
Bennett, Brian J +11 more
core +1 more source
Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
doaj +1 more source
Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]
, 2015 Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO +3 more
core +1 more source
Whole-genome sequencing reveals the genetic mechanisms of domestication in classical inbred mice
Genome Biology, 2022 Background The laboratory mouse was domesticated from the wild house mouse. Understanding the genetics underlying domestication in laboratory mice, especially in the widely used classical inbred mice, is vital for studies using mouse models. However, the
Ming Liu +21 more
doaj +1 more source