Results 151 to 160 of about 762,246 (298)

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham, Meghan McPherson, Lillian Lim, Roberta A. Berard, Matthew Berkowitz, Jean‐Philippe Proulx‐Gauthier, Brian M. Feldman, Nicole Johnson, Dax G. Rumsey, Heinrike Schmeling, Lori B. Tucker, Thomas Loughin, Kristin M. Houghton, Jaime Guzman, The CAPRI Registry Investigators   +14 more
wiley   +1 more source

Farnesoid x Receptor Deficiency Promotes Hepatocytic Injury in Cyp2c70-Deficient Mice With a Human-Like Bile Acid Composition. [PDF]

Liver Int
de Vries HD, Li J, Ustyantsev K, Hovingh MV, Mulder NL, Havinga R, Palmiotti A, de Bruyn K, Attema B, Weersing E, Thomas RE, Bloks VW, Berezikov E, van Faassen M, Verkade HJ, de Boer JF, Kuipers F.   +16 more
europepmc   +1 more source

Perceived Impacts and Predictors of Cannabis Products used by Rheumatology Patients in Alberta: A Multivariable Analysis of Cross‐sectional Survey Data

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among rheumatology patients, and their associations with patient factors, patient reported perceived side effects and positive impacts. Methods An online survey (delivered from March to November 2022) was distributed by Alberta Health Services to ...
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Modification of early behavioural, physiological and neuropathological endpoints by syntaxin-6 knockout in a humanised P301S transgenic model of tauopathy. [PDF]

Acta Neuropathol
Hill E, Linehan J, Farmer M, Jakubcova T, Hamdan S, Tomlinson A, Purro S, Argentina F, Jones E, Kaye N, Fitzhugh C, de Silva R, Brandner S, Collinge J, Cunningham TJ, Mead S.   +15 more
europepmc   +1 more source

From Knockout Mice to Knockout Rats [PDF]

Neurosurgery, 2003
openaire   +1 more source

Associations of lifestyle‐related factors and psoriatic arthritis disease activity: the Dutch south west psoriatic arthritis study

Arthritis Care &Research, Accepted Article.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients newly diagnosed with PsA, between 2013 and 2023. A composite lifestyle risk score (range 0 to 5) was calculated using five lifestyle‐
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source

Low-Salt Diet Induces Claudin-3 Expression and Drives Adaptive Changes in Collecting Duct of Claudin-3-Deficient Mice. [PDF]

Acta Physiol (Oxf)
Sassi A, Chassot A, Jellali S, Liaudet N, Polat A, Baier F, Stroka D, Furuse M, Feraille E.   +8 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

IFI204-STING drives protective innate immunity against gangrenous <i>Clostridium perfringens</i> infection via regulation of NLRP3 signaling. [PDF]

Front Immunol
Zhang MY, Li JQ, Xu Q, Zhuang ZJ, Liang J, He AB, Zhang SX, Zhao Y, Chen X, Li ZY, Sheng P, Liu Y, Yu SX.   +12 more
europepmc   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source