Results 61 to 70 of about 256,488 (286)
Virulence, 2018 Staphylococcus aureus infections are becoming a major global health issue due to the rapid emergence of multidrug-resistant strains. Therefore, there is an urgent need to develop an effective vaccine to prevent and control these infections.
Miriam Moscoso +4 more
doaj +1 more source
Biological effects of agricultural bio-materials on some blood and tissue factors in Balb/c mice [PDF]
The Iranian Journal of Veterinary Science and Technology, 2020 Pseudomonas infections are an important cause of morbidity and mortality and saprophytic fungi are now increasingly being recognized as serious pathogens in immunocompromised patients.To investigate the effect of using bio-materials on mammalian tissues ...
Manijeh Rostaminia +4 more
doaj +1 more source
A Salmonella virulence factor activates the NOD1/NOD2 signaling pathway. [PDF]
, 2011 The invasion-associated type III secretion system (T3SS-1) of Salmonella enterica serotype Typhimurium (S. Typhimurium) activates the transcription factor NF-κB in tissue culture cells and induces inflammatory responses in animal models through unknown ...
Bäumler, Andreas J +7 more
core +2 more sources
Impaired peripheral nerve regeneration in a mutant strain of mice (Enr) with a Schwann cell defect [PDF]
The Journal of Neuroscience, 1995 Schwann cell-axon interactions in the development, maintenance, and regeneration of the normal peripheral nervous system are complex. A previously described transgene-induced insertional mutation (BPFD#36), now referred to as Enervated (Enr), results in disrupted Schwann cell- axon interactions.
E M, Rath +3 more
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Viruses, 2016 West Nile virus (WNV) strains may differ significantly in neuroinvasiveness in vertebrate hosts. In contrast to genetic lineage 1 WNVs, molecular determinants of pathogenic lineage 2 strains have not been experimentally confirmed so far.
Katalin Szentpáli-Gavallér +8 more
doaj +1 more source
Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice [PDF]
Experimental Eye Research, 2012 Elevated intraocular pressure (IOP) is a causative risk factor for the development and progression of glaucoma. Glaucomatous mutations in myocilin (MYOC) damage the trabecular meshwork and elevate IOP in humans and in mice. Animal models of glaucoma are important to discover and better understand molecular pathogenic pathways and to test new glaucoma ...
McDowell, Colleen M +8 more
openaire +3 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Scientific ReportsTelomeres are terminal protective chromosome structures. Genetic variants in genes coding for proteins required for telomere maintenance cause rare, life-threatening Telomere Biology Disorders (TBDs) such as dyskeratosis congenita, aplastic anemia or ...
Rosa Guerrero-López +13 more
doaj +1 more source
Gut Microbes, 2020 Mechanisms of host–pathogen interactions resulting in immunopathological responses upon human Campylobacter jejuni infection are not completely understood, but the recent availability of murine infection models mimicking key features of ...
Markus M. Heimesaat +10 more
doaj +1 more source