Lactate Dehydrogenase Inhibition Reverts the Fatty Acid-Induced Neurotoxic Phenotype of Astrocytes. [PDF]
GliaEsteve D +5 more
europepmc +1 more source
Low sociability in BTBR T+tf/J mice is independent of partner strain
, 2012 Mu Yang +7 more
openalex +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion. [PDF]
GliaPhilips T +9 more
europepmc +1 more source
Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus [PDF]
, 2011 Katie Harris +3 more
openalex +1 more source
Long-term exercise training inhibits inflammation by suppressing hippocampal NLRP3 in APP/PS1 mice
, 2023 Xue Li +5 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Context-Dependent Roles of ANGPTL2-Mediated Inflammaging in Tissue Homeostasis, Pathological Tissue Remodeling, and Longevity. [PDF]
Aging CellYumoto S +8 more
europepmc +1 more source