Results 141 to 150 of about 222,369 (326)
Advanced Science, EarlyView.The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen +8 more
wiley +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Advanced Science, EarlyView.A bioinstructive injectable hydrogel enables sustained release of stromal cell–derived factor‐1 alpha (SDF‐1α) and stable retention of laminin through ionic and hydrophobic interactions. This dual‐signaling matrix promotes endogenous stem cell recruitment and training, supports angiogenesis, and enhances intrinsic regenerative processes in ischemic ...
Yurim Kim, Young‐Min Kim
wiley +1 more source
An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis
Advanced Science, EarlyView.Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang +8 more
wiley +1 more source
Temperature Effect on the Nanostructureof SDS Micelles in Water
, 2013 Boualem Hammouda
openalex +1 more source
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
Advanced Science, EarlyView.The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source
Brain-targeting study of stearic acid–grafted chitosan micelle drug-delivery system
International Journal of Nanomedicine, 2012 Yi-Ting Xie, Yong-Zhong Du, Hong Yuan, Fu-Qiang HuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, ChinaPurpose: Therapy for central nervous system disease is mainly restricted by the blood–brain barrier.
Xie YT, Du YZ, Yuan H, Hu FQ
doaj
Advanced Science, EarlyView.This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu +14 more
wiley +1 more source