Results 11 to 20 of about 103,942 (288)
Nanomaterials, 2021 To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang +6 more
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Micro & Nano Letters, 2021 In the present work, docetaxel (DTX) and retinoic acid (RA) co‐loaded micelles were developed for synergistic prostate cancer therapy. PEG‐RA and RA‐PEG‐RA were synthesized and subsequently used for loading of DTX and RA. The as prepared DTX/RA@RA‐PEG‐RA
Hang Hu, Defeng Xu
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Preparation of Two Types of Polymeric Micelles Based on Poly(β-L-Malic Acid) for Antitumor Drug Delivery. [PDF]
PLoS ONE, 2016 Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. In this work, two types of CPT-conjugated polymers were synthesized based on poly(β-L-malic acid) (PMLA) derivatives. Folic acid (FA) was introduced into
Tiehong Yang +6 more
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Biodegradable m-PEG/PCL Core-Shell Micelles: Preparation and Characterization as a Sustained Release Formulation for Curcumin [PDF]
Advanced Pharmaceutical Bulletin, 2014 Purpose: Among the potent anticancer agents, curcumin is known as a very efficacious against many different types of cancer cells, but its clinical applications has been limited because of hydrophobicity, low gastrointestinal absorption, poor ...
Hossein Danafar +4 more
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Pharmaceutics, 2020 To improve the in vivo stability of poly(ε-caprolactone)-b-poly(ethylene glycol) (PCL-PEG)-based micelles and cargo retention by π-π stacking interactions, pendant aromatic rings were introduced by copolymerization of ε-caprolactone with benzyl 5-methyl ...
Yanna Liu +8 more
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Intracellular K+-Responsive Block Copolymer Micelles for Targeted Drug Delivery of Curcumin
Frontiers in Bioengineering and Biotechnology, 2022 Curcumin (CUR) is a natural bioactive compound that has attracted attention as a “golden molecule” due to its therapeutic properties against several types of tumors.
Mingyue Jiang +19 more
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Pharmaceutical Fronts, 2022 Doxorubicin hydrochloride (DOX) is one of the widely used antineoplastic agents in treating various cancers, yet it is always associated with the occurrence of adverse reactions that limit its clinical use.
Ya-Ni Yang, Chen Ge, Jun He, Wei-Gen Lu
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Molecules, 2023 Objective: The objective of this study was to examine the preparation process of DSPE-PEG-C60/NCTD micelles and assess the impact of fullerenol (C60)-modified micelles on the nephrotoxicity and antitumor activity of NCTD.
Zhongpeng Ding +8 more
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Influence of Magnetic Micelles on Assembly and Deposition of Porphyrin J-Aggregates
Nanomaterials, 2020 Clusters of superparamagnetic iron oxide nanoparticles (SPIONs) have been incorporated into the hydrophobic core of polyethylene glycol (PEG)-modified phospholipid micelles. Two different PEG-phospholipids have been selected to guarantee water solubility
Maria Angela Castriciano +7 more
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Asian Journal of Pharmaceutical Sciences, 2014 Polyelectrolyte complex micelles were prepared by self-assembly of polypeptide-based triblock copolymer as a new drug carrier for cancer chemotherapy. The triblock copolymer, poly(l-aspartic acid)-b-poly(ethylene glycol)-b-poly(l-aspartic acid) (PLD-b ...
Jeong Hwan Kim +6 more
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