Results 11 to 20 of about 222,369 (326)

Engineering micelles with hydrophilic-lipophilic balance to overcome intestinal barrier for oral therapeutic application [PDF]

open access: yesMaterials Today Bio
The primary challenge in developing oral nanocarriers lies in achieving a balance between mucus penetration and cellular endocytosis. Overcoming this dilemma tends to require multiple surface properties on design of nanocarriers, but it is not favorable ...
Kedong Liu   +5 more
doaj   +2 more sources

Sorafenib Nanomicelles Effectively Shrink Tumors by Vaginal Administration for Preoperative Chemotherapy of Cervical Cancer

open access: yesNanomaterials, 2021
To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang   +6 more
doaj   +1 more source

Co‐delivery of docetaxel and retinoic acid by poly (ethylene glycol)‐retinoic acid conjugates based micelles for synergistic prostate cancer therapy

open access: yesMicro & Nano Letters, 2021
In the present work, docetaxel (DTX) and retinoic acid (RA) co‐loaded micelles were developed for synergistic prostate cancer therapy. PEG‐RA and RA‐PEG‐RA were synthesized and subsequently used for loading of DTX and RA. The as prepared DTX/RA@RA‐PEG‐RA
Hang Hu, Defeng Xu
doaj   +1 more source

Preparation of Two Types of Polymeric Micelles Based on Poly(β-L-Malic Acid) for Antitumor Drug Delivery. [PDF]

open access: yesPLoS ONE, 2016
Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. In this work, two types of CPT-conjugated polymers were synthesized based on poly(β-L-malic acid) (PMLA) derivatives. Folic acid (FA) was introduced into
Tiehong Yang   +6 more
doaj   +1 more source

Biodegradable m-PEG/PCL Core-Shell Micelles: Preparation and Characterization as a Sustained Release Formulation for Curcumin [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2014
Purpose: Among the potent anticancer agents, curcumin is known as a very efficacious against many different types of cancer cells, but its clinical applications has been limited because of hydrophobicity, low gastrointestinal absorption, poor ...
Hossein Danafar   +4 more
doaj   +1 more source

Self-assembly of Tween 80 micelles as nanocargos for oregano and trans-cinnamaldehyde plant-derived compounds [PDF]

open access: yes, 2020
The self-assembly of Tween 80 (T80) micelles loaded with plant-based oregano essential oil (OR) and trans-cinnamaldehyde (TCA) was studied. The effect of different factors, including the surfactant to oil ratio, the presence of sodium chloride, thermal ...
Claeys, Myriam   +4 more
core   +1 more source

π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy

open access: yesPharmaceutics, 2020
To improve the in vivo stability of poly(ε-caprolactone)-b-poly(ethylene glycol) (PCL-PEG)-based micelles and cargo retention by π-π stacking interactions, pendant aromatic rings were introduced by copolymerization of ε-caprolactone with benzyl 5-methyl ...
Yanna Liu   +8 more
doaj   +1 more source

Optical evidence for adsorption of charged inverse micelles in a Stern layer [PDF]

open access: yes, 2020
Understanding the properties and behavior of nonpolar liquids containing surfactant and colloidal particles is essential for applications such as electrophoretic ink displays and liquid toner printing.
Beales, Graham   +7 more
core   +2 more sources

Novel Worm-like Micelles for Hydrochloride Doxorubicin Delivery: Preparation, Characterization, and In Vitro Evaluation

open access: yesPharmaceutical Fronts, 2022
Doxorubicin hydrochloride (DOX) is one of the widely used antineoplastic agents in treating various cancers, yet it is always associated with the occurrence of adverse reactions that limit its clinical use.
Ya-Ni Yang, Chen Ge, Jun He, Wei-Gen Lu
doaj   +1 more source

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