Results 11 to 20 of about 125,431 (305)

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice [PDF]

open access: yesAdvanced science
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Li Y   +6 more
europepmc   +2 more sources

NCLX Inhibition plus Ca<sup>2+</sup> Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma. [PDF]

open access: yesAdv Sci (Weinh)
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Zhao C   +7 more
europepmc   +2 more sources

Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery

open access: yesInternational Journal of Nanomedicine, 2014
Ziming Zhao,1,2,* Yu Wang,1,2,* Jin Han,1,2 Keli Wang,1 Dan Yang,1,2 Yihua Yang,1,2 Qian Du,1,2 Yuanjian Song,3 Xiaoxing Yin1,2 1Department of Pharmacy, 2Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, 3Department of Basic Medical ...
Zhao ZM   +8 more
doaj   +1 more source

Sorafenib Nanomicelles Effectively Shrink Tumors by Vaginal Administration for Preoperative Chemotherapy of Cervical Cancer

open access: yesNanomaterials, 2021
To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang   +6 more
doaj   +1 more source

Co‐delivery of docetaxel and retinoic acid by poly (ethylene glycol)‐retinoic acid conjugates based micelles for synergistic prostate cancer therapy

open access: yesMicro & Nano Letters, 2021
In the present work, docetaxel (DTX) and retinoic acid (RA) co‐loaded micelles were developed for synergistic prostate cancer therapy. PEG‐RA and RA‐PEG‐RA were synthesized and subsequently used for loading of DTX and RA. The as prepared DTX/RA@RA‐PEG‐RA
Hang Hu, Defeng Xu
doaj   +1 more source

Preparation of Two Types of Polymeric Micelles Based on Poly(β-L-Malic Acid) for Antitumor Drug Delivery. [PDF]

open access: yesPLoS ONE, 2016
Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. In this work, two types of CPT-conjugated polymers were synthesized based on poly(β-L-malic acid) (PMLA) derivatives. Folic acid (FA) was introduced into
Tiehong Yang   +6 more
doaj   +1 more source

Phase behavior of flowerlike micelles in a SCF cell model [PDF]

open access: yes, 2008
We study the interactions between flowerlike micelles, self-assembled from telechelic associative polymers, using a molecular self-consistent field (SCF) theory and discuss the corresponding phase behavior.
Besseling, N.A.M.   +2 more
core   +3 more sources

Aromatic micelles: toward a third-generation of micelles

open access: yesProceedings of the Japan Academy, Series B, 2023
Micelles are useful and widely applied molecular assemblies, formed from amphiphilic molecules, in water. The majority of amphiphiles possess an alkyl chain as the hydrophobic part. Amphiphiles bearing hydrophilic and hydrophobic polymer chains generate so-called polymeric micelles in water.
YOSHIZAWA, Michito, CATTI, Lorenzo
openaire   +2 more sources

Biodegradable m-PEG/PCL Core-Shell Micelles: Preparation and Characterization as a Sustained Release Formulation for Curcumin [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2014
Purpose: Among the potent anticancer agents, curcumin is known as a very efficacious against many different types of cancer cells, but its clinical applications has been limited because of hydrophobicity, low gastrointestinal absorption, poor ...
Hossein Danafar   +4 more
doaj   +1 more source

π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy

open access: yesPharmaceutics, 2020
To improve the in vivo stability of poly(ε-caprolactone)-b-poly(ethylene glycol) (PCL-PEG)-based micelles and cargo retention by π-π stacking interactions, pendant aromatic rings were introduced by copolymerization of ε-caprolactone with benzyl 5-methyl ...
Yanna Liu   +8 more
doaj   +1 more source

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