Results 61 to 70 of about 209,966 (301)

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

open access: yesAdvanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang   +8 more
wiley   +1 more source

Core-Crosslinked Polymeric Micelles: Principles, Preparation, Biomedical Applications and Clinical Translation

open access: yesNano Today, 2015
Polymeric micelles (PM) are extensively used to improve the delivery of hydrophobic drugs. Many different PM have been designed and evaluated over the years, and some of them have steadily progressed through clinical trials. Increasing evidence suggests,
M. Talelli   +5 more
semanticscholar   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

open access: yesAdvanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole   +17 more
wiley   +1 more source

The synthesis and ring-opening polymerisation of novel cyclic esters from malic acid [PDF]

open access: yes
The work in this thesis is directed towards the preparation of cyclic ester monomers using malic acid as a renewable resource. Their subsequent controlled ring-opening polymerisation (ROP) to yield functionalised poly(ester)s is studied and ...
Pounder, Ryan J.
core  

Ultra-High to Ultra-Low Drug Loaded Micelles: Probing Host-Guest Interactions by Fluorescence Spectroscopy

open access: yes, 2019
Polymer micelles are an attractive means to solubilize water insoluble compounds such as drugs. Drug loading, formulations stability and control over drug release are crucial factors for drug loaded polymer micelles.
Michael M, Lübtow   +5 more
core   +1 more source

Novel Soluplus(®)-TPGS mixed micelles for encapsulation of paclitaxel with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines.

open access: yesColloids and Surfaces B: Biointerfaces, 2016
The aim of this work was to develop mixed micelles based on two biocompatible copolymers of polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (Soluplus(®)) and D-α-tocopheryl polyethylene-glycol 1000 succinate (TPGS), to improve the aqueous ...
E. Bernabeu   +5 more
semanticscholar   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

open access: yesAdvanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai   +8 more
wiley   +1 more source

Development of polymeric micelles for targeting intractable cancers

open access: yesCancer Science, 2016
In relation to recent advances in nanobiotechnologies, cancer‐targeted therapy using nano‐scaled drug carriers (nanocarriers) has been attracting enormous attention with success in clinical studies.
N. Nishiyama, Y. Matsumura, K. Kataoka
semanticscholar   +1 more source

A New Customizable Surfactant LLPS Strategy for Sustainable and Highly Efficient Radioactive Metal Ion Separation

open access: yesAdvanced Science, EarlyView.
A diluent‐free, customizable liquid–liquid phase separation (LLPS) platform enables highly efficient radioactive metal ion extraction and stripping. By encapsulating hydrophobic extractants into an ionic surfactant‐rich condensed phase, this LLPS system leverages synergistic electrostatic and coordination interactions.
Ruihan Yan   +7 more
wiley   +1 more source

Detection of hydrogen peroxide with chemiluminescent micelles

open access: yes, 2008
Dongwon Lee1, Venkata R Erigala1,3, Madhuri Dasari1, Junhua Yu2, Robert M Dickson2, Niren Murthy11The Wallace H. Coulter Department of Biomedical Engineering; 2Department of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA ...
Robert M Dickson   +5 more
core  

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