Results 181 to 190 of about 24,159 (244)

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe, Josef Wachtveitl, Alexander Heckel, Florian Buhr, Sabrina Toews, Thomas M. Schimmer   +5 more
wiley   +2 more sources

Bioengineered extracellular vesicles escape lysosomal degradation and deliver Tet-PKM2 for macrophage immunometabolic reprogramming and periodontitis treatment. [PDF]

Bioact Mater
Zhang WJ, Tian BM, Li F, Li X, Wu RX, Yin Y, Wang J, Deng DK, Chen YZ, Wang HY, Du YX, Wang X, Xiao Y, He XT, Chen FM.   +14 more
europepmc   +1 more source

Investigating mind-matter-interactions [PDF]

Jakob, Marissa-Julia
core  

Multiple Periapical Lesions Influence the Expression of TLR4/NF‐κB Pathway Components and the Development of Hepatic Injuries in Healthy and Chronic Alcohol‐Consuming Rats

International Endodontic Journal, Volume 59, Issue 5, Page 863-872, May 2026.
ABSTRACT Aim To evaluate the impact of multiple apical periodontitis (AP) on the expression of TLR4/NF‐κB pathway components, proinflammatory cytokine levels, and development of hepatic injuries in rats with and without chronic alcohol consumption. Methodology Thirty‐two rats were assigned to four groups (n = 8): Control, AP, Alcohol, and Alcohol+AP ...
Karem Paula Pinto, Isabelle da Cunha Degani, Jenif Braga de Souza, Renata Heisler Neves, Luciana Brandão‐Bezerra, Luciana Moura Sassone, Emmanuel João Nogueira Leal da Silva   +6 more
wiley   +1 more source

Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G., Kamini Shivhare, Piyush Kumar Gupta, Amirhossein Sahebkar, Prashant Kesharwani, Rahul Shukla   +5 more
wiley   +1 more source

Technical guidelines for non-clinical pharmacological research of traditional Chinese medicine (TCM) formulae. [PDF]

Chin Med
Li W, Zhang F, Wang P, Zhang Y, Cao P, Ma Z, Yao H, Wang J, Yang H, Xu H.   +9 more
europepmc   +1 more source

Electrochemical CO2 Reduction on a Bi–Sn Eutectic Alloy in Acidic Media for Formic Acid Production

ChemSusChem, Volume 19, Issue 8, 28 April 2026.
Acidic CO2 electrolysis enables direct formic acid production with minimal (bi)carbonate formation. A eutectic Bi–Sn gas‐diffusion electrode achieves 81.3% faradaic efficiency (FE) at −100 mA cm−2 and pH 3, retaining selectivity up to −400 mA cm−2 and stable operation for 100 h with < 10% FE loss.
Avni Guruji, Alejandro Cañete‐Arché, Yuvraj Y. Birdja, Ranjith Prasannachandran, Max García‐Melchor, Deepak Pant   +5 more
wiley   +1 more source

Interferon stimulatory DNA activates the DNA damage signaling through ATM and DNA-PK sensing. [PDF]

J Biol Chem
Kemiha S, Rejón-Franco L, Ghibaudo E, Eloiflin RJ, Chemarin M, Hawillo K, Laguette N, Técher H.   +7 more
europepmc   +1 more source

Protocol for performing traumatic spinal cord injury surgery on mice in germ-free isolators and assessing injury recovery and pathophysiology. [PDF]

STAR Protoc
Mifflin KA, Kigerl KA, Hudson LC, Guan Z, Popovich PG.   +4 more
europepmc   +1 more source

Pharmacokinetic-pharmacodynamic modeling to evaluate the relative impact of immune response and meropenem on bacterial killing <i>in vivo</i>. [PDF]

Antimicrob Agents Chemother
Saporta R, Tassi N, Biordi V, Ticha O, Ginosyan A, Loryan I, Nielsen EI, Bekeredjian-Ding I, Kerscher B, Friberg LE.   +9 more
europepmc   +1 more source