Results 11 to 20 of about 1,377,297 (250)

Testing the Effects of Personality-Related Beliefs on Micro-PK

open access: yesJournal of Anomalous Experience and Cognition
Objective.This preregistered study investigates mind-matter interactions by testing observer effects on quantum random number generator (QRNG) outcomes mediated by implicit intentions. Methods. We evaluated participants' personality traits (PTs), and presented them with goal-related or neutral stimuli based on QRNG outputs. We predicted deviations from
Marissa-Julia Jakob   +2 more
core   +4 more sources

Local Solvent Ordering Drives Supramolecular Chirality Inversion. [PDF]

open access: yesAdv Sci (Weinh)
Local solvent organization is shown to govern supramolecular chirality by selecting distinct chiral assembly pathways. A subtle change in water‐DMSO composition reverses the helical sense of a chiral perylene bisimide, while heating induces an irreversible thermal inversion to a more stable enantiomorph.
Pal T   +4 more
europepmc   +2 more sources

Effects of Foliar-Applied Mixed Mineral Fertilizers and Organic Biostimulants on the Growth and Hybrid Seed Production of a Male-Sterile Inbred Maize Line

open access: yesPlants, 2023
Plants of inbred maize lines are characterized by low vigor due to their high rates of homozygosity and may, therefore, benefit from additional nutrients and biostimulants supplied via foliar spraying.
Riccardo Boscaro   +6 more
doaj   +1 more source

QupKake: Integrating Machine Learning and Quantum Chemistry for micro-pKa Predictions

open access: yesJournal of Chemical Theory and Computation, 2023
Accurate prediction of micro-pKa values is crucial for understanding and modulating the acidity and basicity of organic molecules, with applications in drug discovery, materials science, and environmental chemistry. This work introduces QupKake, a novel workflow that combines graph neural network (GNN) models with semiempirical quantum mechanical (QM ...
Omri D. Abarbanel, Geoffrey R. Hutchison
openaire   +2 more sources

Intentional Observer Effects on Quantum Randomness: A Bayesian Analysis Reveals Evidence Against Micro-Psychokinesis

open access: yesFrontiers in Psychology, 2018
Intentional effects of human observation on the output of quantum-based random number generators (tRNG) have been studied for decades now. This research has been known as micro-psychokinesis (micro-PK) and many studies in the field reported evidence for ...
Markus A. Maier   +2 more
doaj   +1 more source

Dose Optimization of Aditoprim-Sulfamethoxazole Combinations Against Trueperella pyogenes From Patients With Clinical Endometritis by Using Semi-mechanistic PK/PD Model

open access: yesFrontiers in Pharmacology, 2021
Combinations of two and more drugs with different target sites are being used as a new treatment regimen for resistant clones of bacteria. Though, achieving the right combination of the drugs for optimal dosage regimen is challenging.
Muhammad Kashif Maan   +11 more
doaj   +1 more source

PK-PD Modeling and Optimal Dosing Regimen of Acetylkitasamycin against Streptococcus suis in Piglets

open access: yesAntibiotics, 2022
Streptococcus suis (S. suis) causes severe respiratory diseases in pigs and is also an important pathogen causing hidden dangers to public health and safety.
Anxiong Huang   +10 more
doaj   +1 more source

Dose optimisation based on pharmacokinetic/pharmacodynamic target of tigecycline

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Tigecycline, a new first-in-class glycylcycline antibiotic, has shown promising efficacy against a broad range of micro-organisms. It is widely prescribed for various infections, with most prescriptions being considered for off-label use. However, only
Bing Leng   +5 more
doaj   +1 more source

The complexity of $P$4-decomposition of regular graphs and multigraphs [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2015
Let G denote a multigraph with edge set E(G), let µ(G) denote the maximum edge multiplicity in G, and let Pk denote the path on k vertices. Heinrich et al.(1999) showed that P4 decomposes a connected 4-regular graph G if and only if |E(G)| is ...
Ajit Diwan   +4 more
doaj   +1 more source

Evaluation of biosimilarity of RinGlar® (GEROPHARM LLC, Russia) and Lantus® (Sanofi-Aventis Deutschland GmbH, Germany) using the euglycemic hyperinsulinemic clamp technique in patients with type 1 diabetes: double-blind randomized clinical trial

open access: yesСахарный диабет, 2020
Background: Prevention of the development of micro-and macrovascular complications in patients with diabetes melli-tus (DM) encouraged the search for insulin analogues that allow imitating, as close as possible, a normal physiological insulin secretion ...
Alexander Y. Mayorov   +8 more
doaj   +1 more source

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