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Analysis of Gene Expression Profile of AGS Cells Stimulated by Helicobacter pylori Adhesion

open access: yesGut and Liver, 2007
Background/Aims: Interactions between H. pylori and gastric epithelial cells contribute to gastric inflam-mation and epithelial damage. This study was performed to evaluate the gene expression profile of AGS cells by adhesion of H. pylori.
doaj   +1 more source

Identification of potential biomarkers and pathways related to major depressive disorder by integrated bioinformatic analysis and experimental validation

open access: yesAsian Pacific Journal of Tropical Biomedicine
Objective: To identify promising biomarkers for the pathogenesis of major depressive disorder (MDD). Methods: Microarray chips of MDD patients, including the GSE98793, GSE52790, and GSE39653 datasets, were obtained from the Gene Expression Omnibus ...
Ying Zeng   +5 more
doaj   +1 more source

Identification of Potential Therapeutic Targets Against Anthrax-Toxin-Induced Liver and Heart Damage

open access: yesToxins
Anthrax represents a disease resulting from infection by toxin-secreting bacteria, Bacillus anthracis. This research aimed to identify new therapeutic targets to combat anthrax.
Lihong Wu   +10 more
doaj   +1 more source

A Meta‐Analysis of the Effects of Early Life Stress on the Prefrontal Cortex Transcriptome Reveals Long‐Term Downregulation of Myelin‐Related Gene Expression

open access: yesBrain and Behavior
Background Early life stress (ELS) refers to exposure to negative childhood experiences, such as neglect, disaster, and physical, mental, or emotional abuse.
Toni Q. Duan   +12 more
doaj   +1 more source

Transcriptome and Metabolome Analyses Reveal That Nitrate Strongly Promotes Nitrogen and Carbon Metabolism in Soybean Roots, but Tends to Repress It in Nodules

open access: yesPlants, 2018
Leguminous plants form root nodules with rhizobia that fix atmospheric dinitrogen (N2) for the nitrogen (N) nutrient. Combined nitrogen sources, particular nitrate, severely repress nodule growth and nitrogen fixation activity in soybeans (Glycine max [L.
Shinji Ishikawa   +5 more
doaj   +1 more source

Oligonucleotide Microarrays Identified Potential Regulatory Genes Related to Early Outward Arterial Remodeling Induced by Tissue Plasminogen Activator

open access: yesFrontiers in Physiology, 2019
Constrictive vascular remodeling limiting blood flow, as well as compensatory outward remodeling, has been observed in many cardiovascular diseases; however, the underlying mechanisms regulating the remodeling response of the vessels remain unclear ...
Olga Plekhanova   +8 more
doaj   +1 more source

Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)

open access: yesFrontiers in Pharmacology, 2018
Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants.
Mohamed E. M. Saeed   +4 more
doaj   +1 more source

Bioinformatics Analysis of Key micro-RNAs and mRNAs under the Hand, Foot, and Mouth Disease Virus Infection [PDF]

open access: yesPolish Journal of Microbiology, 2020
SHENG LIN   +4 more
doaj   +1 more source

Global Tumor RNA Expression in Early Establishment of Experimental Tumor Growth and Related Angiogenesis following Cox-Inhibition Evaluated by Microarray Analysis

open access: yesCancer Informatics, 2007
Altered expression of COX-2 and overproduction of prostaglandins, particularly prostaglandin E2, are common in malignant tumors. Consequently, non-steroidal anti-inflammatory drugs (NSAIDs) attenuate tumor net growth, tumor related cachexia, improve ...
Kent Lundholm   +4 more
doaj  

Chronic constriction injury of sciatic nerve changes circular RNA expression in rat spinal dorsal horn

open access: yesJournal of Pain Research, 2017
Song Cao,1,2,* Wenwen Deng,3,* Ying Li,1 Bangyong Qin,1 Lin Zhang,2 Shouyang Yu,2 Peng Xie,2 Zhi Xiao,4 Tian Yu2 1Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, 2Guizhou Key Laboratory of Anesthesia and Organ Protection ...
Cao S   +8 more
doaj  

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