Results 171 to 180 of about 907,938 (379)
Minimum information about a microarray experiment (MIAME)—toward standards for microarray data
Nature Genetics, 2001 A. Brazma +23 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Advanced Science, EarlyView.Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu +5 more
wiley +1 more source
ONCOMINE: a cancer microarray database and integrated data-mining platform.
Neoplasia, 2004 D. Rhodes +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer +18 more
wiley +1 more source
Screening for candidate genes related to breast cancer with cDNA microarray analysis
, 2015 Yujuan Xiang +10 more
openalex +1 more source
GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox1[w]
Plant Physiology, 2004 Philip Zimmermann +3 more
semanticscholar +1 more source