Results 201 to 210 of about 515,000 (271)

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

Advanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou, Chao Dong, Xiaochun Shen, Pengbo Wang, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Chengxiang Xu, Kaipeng Duan, Dongbao Li, Jin Zhou   +11 more
wiley   +1 more source

Choice of Drug for Malaria Prevention During Pregnancy Does Not Affect Infant Serologic Responses to Plasmodium falciparum Erythrocyte Membrane Proteins 1. [PDF]

Open Forum Infect Dis
Ouattara A, Andronescu LR, Adams M, Sharma A, Nakajima R, Jain A, Taghavian O, Jasinskas A, Felgner PL, Mathanga DP, Chinkhumba J, Laufer MK, Travassos MA.   +12 more
europepmc   +1 more source

Prenatal diagnosis by chromosomal microarray analysis.

Fertility and Sterility, 2018
B. Levy, R. Wapner
semanticscholar   +1 more source

The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

Advanced Science, EarlyView.
This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan, Xuechao Wu, Jinxu Zhou, Weiqi Wu, Yuanliang Cao, Cuiping Sun, Zheng Li, Zhicheng Gong, Hong Tang, Qilin Li, Junsheng Chu, Qing Wang, Kaisa Cui, Xiaojie Lu   +13 more
wiley   +1 more source

Identification and Validation of Key Biomarkers in the Proximal Aqueous Humor Outflow Pathway. [PDF]

Curr Issues Mol Biol
Du R, Yang E, Clark M, Wang N, Du Y.
europepmc   +1 more source

IRF8 Drives Conventional Type 1 Dendritic Cell Differentiation and CD8+ T Cell Activation to Aggravate Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan, Li Shu, Yidan Zheng, Yidong Wang, Mengsha Zheng, Jie Sun, Jiantao Fu, Zihao Zhou, Shen Song, Zhenjie Liu, Fei Li, Zhejun Cai   +11 more
wiley   +1 more source

Enhanced leukemia prediction using hybrid ant colony and ant lion optimization for gene selection and classification. [PDF]

MethodsX
D S, Rajaram G, R E, J V, I G, J R.
europepmc   +1 more source

Single Test‐Based Diagnosis and Subtyping of Pulmonary Hypertension Caused by Fibrosing Mediastinitis Using Plasma Metabolic Analysis

Advanced Science, EarlyView.
Pulmonary hypertension caused by fibrosing mediastinitis has a five‐year survival rate of just 56%. Current diagnostic approaches are complex for patients with mobility limitations and can lead to misdiagnoses due to their nonspecific clinical features.
Yating Zhao, Chunmeng Ding, Hongling Su, Aqian Wang, Aiping Tang, Hongfan Zhao, Ya Ma, Min Zhang, Wanshan Liu, Ruimin Wang, Ziyue Zhang, Shouzhi Yang, Dingyitai Liang, Yida Huang, Kun Qian, Lin Huang, Qihua Fu, Yunshan Cao   +17 more
wiley   +1 more source

Microarray-Based Avidity Assay for Assessment of Thyroid Autoantibodies. [PDF]

Diagnostics (Basel)
Savvateeva E, Sokolova V, Yukina M, Nuralieva N, Kulagina E, Donnikov M, Kovalenko L, Kazakova M, Troshina E, Gryadunov D.   +9 more
europepmc   +1 more source