Results 201 to 210 of about 695,874 (306)

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

Advanced Science, EarlyView.
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti, Linda Popella, Jörg Vogel, Hans M. Maric   +3 more
wiley   +1 more source

Detection of Multiple Allergen-specific IgEs on Microarrays by Immunoassay with Rolling Circle Amplification [PDF]

, 2000
Steve Wiltshire, Shawn M. O'Malley, Jérémy Lambert, Kari Kukanskis, David Edgar, Stephen F. Kingsmore, Barry Schweitzer   +6 more
openalex   +1 more source

An updated comparison of microarray and RNA-seq for concentration response transcriptomic study: case studies with two cannabinoids, cannabichromene and cannabinol. [PDF]

BMC Genomics
Gao X, Yourick MR, Campasino K, Zhao Y, Sepehr E, Vaught C, Sprando RL, Yourick JJ.   +7 more
europepmc   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

A NONPARAMETRIC SCORING ALGORITHM FOR IDENTIFYING INFORMATIVE GENES FROM MICROARRAY DATA [PDF]

, 2000
Peter J. Park, Marcello Pagano, Marco Bonetti   +2 more
openalex   +1 more source

Dengue virus modulates critical cell cycle regulatory proteins in human megakaryocyte cells. [PDF]

Sci Rep
Basak S, Dutta S, Khanal S, Neelakanta G, Sultana H.   +4 more
europepmc   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

Advanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai, Xuan Lu, Xu Yan, Han Su, Yuejun Lin, Zhaowei Jiang, Zhixian Zong, Haixing Wang, Leo Yik Chun Yan, Xiaoting Zhang, Ming Wang, Zhengmeng Yang, Jiakang Jin, Yaofeng Wang, Wayne Yuk‐Wai Lee, Xiaohua Jiang, Ho Ko, Lu Feng, Micky D. Tortorella, Sien Lin, Gang Li   +20 more
wiley   +1 more source

Detecting Gene Copy Number Fluctuations in Tumor Cells by Microarray Analysis of Genomic Representations [PDF]

, 2000
R. Lucito
openalex   +1 more source

Usutu Virus Antibody Dynamics in Naturally Infected Blackbirds, the Netherlands, 2016-2018. [PDF]

Emerg Infect Dis
de Bruin E, van Irsel J, Chandler F, Kohl R, van de Voorde T, van der Linden A, de Boer F, Koopmans M, van der Jeugd H, Reusken C.   +9 more
europepmc   +1 more source

In Situ Electrically Resettable Field‐Effect Transistor Biosensors for Continuous and Multiplexed Neurotransmitter Detection

Advanced Science, EarlyView.
The research team integrated a potentiometrically controlled pH electrode with carbon nanotube (CNT) field‐effect transistor (FET) biosensors on a single chip using compatible processes. By employing zonal modification and optimized pH‐sensitive probes, they achieved simultaneous quadruple‐target detection and tenfold reusability under physiological ...
Bo Xiao, Tingxian Li, Xianmao Cao, Yang Zhang, Jianping He, Mengmeng Xiao, Zhiyong Zhang   +6 more
wiley   +1 more source