Results 61 to 70 of about 106,998 (275)

Microbe-Associated Molecular Patterns-Triggered Root Responses Mediate Beneficial Rhizobacterial Recruitment in Arabidopsis       [PDF]

Plant Physiology, 2012
Abstract This study demonstrated that foliar infection by Pseudomonas syringae pv tomato DC3000 induced malic acid (MA) transporter (ALUMINUM-ACTIVATED MALATE TRANSPORTER1 [ALMT1]) expression leading to increased MA titers in the rhizosphere of Arabidopsis (Arabidopsis thaliana).
Venkatachalam, Lakshmanan, Sherry L, Kitto, Jeffrey L, Caplan, Yi-Huang, Hsueh, Daniel B, Kearns, Yu-Sung, Wu, Harsh P, Bais   +6 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Anticipation of Danger: Microbe-Associated Molecular Pattern Perception Enhances AtPep-Triggered Oxidative Burst   [PDF]

Plant Physiology, 2013
Abstract The endogenous Arabidopsis (Arabidopsis thaliana) peptides, AtPeps, elicit an innate immune response reminiscent of pattern-triggered immunity. Detection of various danger signals, including microbe-associated molecular patterns (MAMPs), leads to elevated transcription of PROPEPs, the AtPep precursors, and PEPRs, the AtPep ...
Flury, Pascale, Klauser, Dominik, Schulze, Birgit, Boller, Thomas, Bartels, Sebastian   +4 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Exposure to inorganic arsenic can lead to gut microbe perturbations and hepatocellular carcinoma

Acta Pharmaceutica Sinica B, 2016
Arsenic is a carcinogenic environmental factor found in food and drinking water around the world. The mechanisms in which arsenic alters homeostasis are not fully understood.
Jonathan Choiniere, Li Wang
doaj   +1 more source

Xanthan pyruvilation is essential for the virulence of Xanthomonas campestris pv. campestris [PDF]

, 2016
Xanthan, the main exopolysaccharide (EPS) synthesized by Xanthomonas spp., contributes to bacterial stress tolerance and enhances attachment to plant surfaces by helping in biofilm formation.
Bianco, María Isabel, Gudesblat, Gustavo Eduardo, Ielpi, Luis, Marano, María Rosa, Mielnichuk, Natalia, Roeschlin, Roxana Andrea, Toum, Laila, Vojnov, Adrián Alberto, Yaryura, Pablo Marcelo   +8 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Role of Porphyromonas gingivalis in the downregulation of NLRp3 inflammasome in periodontitis

Journal of International Clinical Dental Research Organization, 2022
The innate immune response is the body's first line of defense against pathogens. The innate immune system recognizes pathogens, including bacteria and viruses by engagement of the germline-encoded pattern recognition receptors (PRRs).
Neelam Gavali, Amit Chaudhari, Pramod Waghmare, Yogesh Khadtare, Pooja Shendge, Shubhangi Wadgounkar   +5 more
doaj   +1 more source

Functional dissection of a strong and specific microbe‐associated molecular pattern‐responsive synthetic promoter

Plant Biotechnology Journal, 2015
SummarySynthetic promoters are important for temporal and spatial gene expression in transgenic plants. To identify novel microbe‐associated molecular pattern (MAMP)‐responsivecis‐regulatory sequences for synthetic promoter design, a combination of bioinformatics and experimental approaches was employed.
Lehmeyer, Mona, Kanofsky, Konstantin, Hanko, Erik K. R., Ahrendt, Sarah, Wehrs, Maren, Machens, Fabian, Hehl, Reinhard   +6 more
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source