High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. [PDF]
, 2015 The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose tissue,
Armando, Aaron M +6 more
core +6 more sources
Vibrio proteases for biomedical applications: Modulating the proteolytic secretome of v. alginolyticus and v. parahaemolyticus for improved enzymes production [PDF]
, 2019 Proteolytic enzymes are of great interest for biotechnological purposes, and their large-scale production, as well as the discovery of strains producing new molecules, is a relevant issue.
Ghersi G. +3 more
core +1 more source
Modulation of intestinal microbiota and immunometabolic parameters by caloric restriction and lactic acid bacteria [PDF]
, 2018 The objective of this work was to evaluate the effect of a caloric restriction diet with and without the administration of Lactobacillus fermentum CRL1446, Lactobacillus casei CRL431 and Lactococcus lactis CRL1434, on immunemetabolic parameters and the ...
Abeijon Mukdsi, Maria Claudia +5 more
core +1 more source
Hydrolysis of the Leu-Gly bond of phenylazobenzyl-oxycarbonyl-l-Pro-l-Leu-Gly-l-Pro-D-Arg (a substrate of microbial collagenases) by treponemes isolated from the subgingival plaque of periodontitis patients [PDF]
Current Microbiology, 1990 Cell extracts prepared from several oral treponemes isolated from the subgingival plaque of periodontitis patients showed high enzyme activity toward phenylazobenzyl-oxycarbonyl-l-prolyl-l-leucylglycyl-l-prolyl-d-arginine (a compound used as a substrate for microbial collagenases).
Mäkinen, Kauko K. +3 more
openaire +2 more sources
Frontiers in Bioengineering and Biotechnology, 2019 Intestinal disease or surgical intervention results in local changes in tissue and host-derived factors triggering bacterial virulence. A key phenotype involved in impaired tissue healing is increased bacterial collagenase expression which degrades ...
Dylan Nichols +8 more
doaj +1 more source
An overview on therapeutic potential and various applications of microbial collagenases
Journal of Microbiology and Biotechnology Research, 2017 Collagen is the most widely distributed class of proteins in the human body. Monomers of collagen are constantly being synthesized and degraded throughout the development of a healthy individual to adulthood. The collagenase subfamily found in human matrix (metalloproteinases), are capable of hydrolyzing native collagen under physiological conditions ...
Wamik Azmi +2 more
openaire +1 more source
BMC Musculoskeletal Disorders, 2017 Background To determine the safety and efficacy of collagenase clostridium histolyticum (CCH) injection for the treatment of palmar Dupuytren disease nodules.
Bronier Costas +5 more
doaj +1 more source
Necrotrophic growth of periodontopathogens is a novel virulence factor in oral biofilms [PDF]
, 2017 The oral use of antimicrobial agents embedded in toothpastes and mouth rinses results in an oral microbial massacre with high amounts of dead bacteria in close proximity to few surviving bacteria.
Bernaerts, Kristel +6 more
core +1 more source
Production and characterization of collagenase by Penicillium sp. UCP 1286 isolated from Caatinga soil [PDF]
, 2016 A new Penicillium sp. strain isolated from the soil of Caatinga, a Brazilian Biome (UCP 1286) was selected for collagenase production. Fermentation system allowing obtention of collagenolytic activity about 2.7 times higher than existing data, with the ...
Filho, José Luiz de Lima +6 more
core +1 more source
PLoS ONE, 2020 Bacteria play an important role in the degradation of bone material. However, much remains to be learnt about the structure of their communities in degrading bone, and how the depositional environment influences their diversity throughout the exposure ...
Anne Marie Høier Eriksen +8 more
doaj +1 more source