Results 11 to 20 of about 50 (49)
Characteristics and Evolution of Microbial Drug Resistance in Burned Patients
Abstract Wound infection is a serious complication in burn injury, which is a common form of trauma and an important public health issue. We investigated samples from burn and nonburn wounds for microbial characteristics and temporal trends of antibiotic resistance. Wound samples were collected from 369 burned patients and 927 non-burned
Zhifeng Huang +8 more
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Effectiveness of Antibiotics: Anti-Bacterial Activity or Microbial Drug Resistance?
Antibiotics, both broad- and narrow spectrum, are widely used for treatment of specific infection by a consortium of microorganisms or by a single pathogen, respectively. Oral or intravenous, or even topical administration of different categories of antibiotics in various forms is a common practice round the globe.
Rashed Noor +3 more
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Hygiene: microbial strategies to reduce pathogens and drug resistance in clinical settings
SummaryHealthcare‐associated infections (HAIs) are a global concern, affecting all western hospitals, and profoundly impairing the clinical outcome of up to 15% of all hospitalized patients. Persistent microbial contamination of hospital surfaces has been suggested to contribute to HAIs onset, representing a reservoir for hospital pathogens.
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JAMA: The Journal of the American Medical Association, 1997
The stated intention of Microbial Drug Resistance is to be "an international journal that provides a multi-disciplinary forum for peer reviewed original papers as well as topical reviews and special reports." It focuses primarily upon "the emergence and spread of antibiotic-resistant microbial pathogens and resistance genes, and the challenges they ...
Anne M. Pascarelli, William W. McCloskey
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The stated intention of Microbial Drug Resistance is to be "an international journal that provides a multi-disciplinary forum for peer reviewed original papers as well as topical reviews and special reports." It focuses primarily upon "the emergence and spread of antibiotic-resistant microbial pathogens and resistance genes, and the challenges they ...
Anne M. Pascarelli, William W. McCloskey
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Drug repurposing to overcome microbial resistance
Drug Discovery Today, 2022Infections are a growing global threat, and the number of resistant species of microbial pathogens is alarming. However, the rapid development of cross-resistant or multidrug-resistant strains and the development of so-called 'superbugs' are in stark contrast to the number of newly launched anti-infectives on the market. In this review, I summarize the
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Microbial and viral drug resistance mechanisms
Trends in Microbiology, 2002Microorganisms and viruses have developed numerous resistance mechanisms that enable them to evade the effect of antimicrobials and antivirals. As a result, many have become resistant to almost every available means of treatment. This problem, although not new, is becoming increasingly acute and it is now clear that a fundamental understanding of the ...
Adrian R. Walmsley +2 more
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Biocides, drug resistance and microbial evolution
Current Opinion in Microbiology, 2001Antimicrobial biocides are widely used in critical human health situations in which rigorous infection control is needed. Increasingly, biocidal agents are being marketed for home use, although there is little evidence that they significantly improve home hygiene. Biocide resistance mechanisms share many themes with antibiotic resistance mechanisms.
David G. White, Patrick F. McDermott
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Microbial resistance to drug therapy: A review
American Journal of Infection Control, 1997Microbial resistance to the antimicrobials in standard use is becoming more prevalent. A historical perspective frames further discussion. Bacterial resistance is most common, but resistance has been identified in fungi, viruses, and parasites. Resistance is a complex phenomenon that involves the microorganism, the environment, and the patient ...
Felissa L. Cohen, Donna Tartasky
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1955
Publisher Summary It is unfeasible and unnecessary to coerce the complex biological events contributing to the origin of resistance into a single theory. Experimental evidence suggests that a few models define most examples of resistance development, particularly if the models are so combined as to provide either genotypic or phenotypic alterations ...
Vernon Bryson, Waclaw Szybalski
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Publisher Summary It is unfeasible and unnecessary to coerce the complex biological events contributing to the origin of resistance into a single theory. Experimental evidence suggests that a few models define most examples of resistance development, particularly if the models are so combined as to provide either genotypic or phenotypic alterations ...
Vernon Bryson, Waclaw Szybalski
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Quorum sensing and microbial drug resistance.
Yi chuan = Hereditas, 2016Microbial drug resistance has become a serious problem of global concern, and the evolution and regulatory mechanisms of microbial drug resistance has become a hotspot of research in recent years. Recent studies showed that certain microbial resistance mechanisms are regulated by quorum sensing system.
Lian-Hui Zhang +5 more
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