Results 11 to 20 of about 753,950 (380)

Microbial Persistence and the Road to Drug Resistance [PDF]

Cell Host & Microbe, 2013
Microbial drug persistence is a widespread phenomenon in which a subpopulation of microorganisms is able to survive antimicrobial treatment without acquiring resistance-conferring genetic changes. Microbial persisters can cause recurrent or intractable infections, and, like resistant mutants, they carry an increasing clinical burden.
Cohen, Nadia R., Lobritz, Michael A., Collins, James J.   +2 more
openaire   +3 more sources

Non Microbial Drug Resistance

Chettinad Health City Medical Journal, 2013
Mr Vinayak Meti
semanticscholar   +3 more sources

Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens

Frontiers in Pharmacology, 2021
Antibiotic resistance or microbial drug resistance is emerging as a serious threat to human healthcare globally, and the multidrug-resistant (MDR) strains are imposing major hurdles to the progression of drug discovery programs.
Tushar Khare, Tushar Khare, Uttpal Anand, Abhijit Dey, Yehuda G. Assaraf, Zhe-Sheng Chen, Zhijun Liu, Vinay Kumar, Vinay Kumar   +8 more
doaj   +2 more sources

Microbial extracellular vesicles contribute to antimicrobial resistance.

PLoS Pathogens
With the escalating global antimicrobial resistance crisis, there is an urgent need for innovative strategies against drug-resistant microbes. Accumulating evidence indicates microbial extracellular vesicles (EVs) contribute to antimicrobial resistance ...
Bowei Jiang, Yi Lai, Wenhao Xiao, Tianyu Zhong, Fengping Liu, Junjie Gong, Junyun Huang   +6 more
doaj   +2 more sources

Approaches for Mitigating Microbial Biofilm-Related Drug Resistance: A Focus on Micro- and Nanotechnologies [PDF]

Molecules, 2021
Biofilms play an essential role in chronic and healthcare-associated infections and are more resistant to antimicrobials compared to their planktonic counterparts due to their (1) physiological state, (2) cell density, (3) quorum sensing abilities, (4 ...
Harinash Rao, Sulin Choo, Sri Raja Rajeswari Mahalingam, Diajeng Sekar Adisuri, Priya Madhavan, Abdah Md Akim, Pei Pei Chong   +6 more
openalex   +2 more sources

Demographic and microbial characteristics and drug resistance of childhood tuberculosis in Istanbul: analysis of 1,541 cases

Journal of Infection in Developing Countries, 2014
INTRODUCTION Although tuberculosis (TB) is frequently seen in Turkey, there are limited studies on childhood TB. We aimed to describe clinical and laboratory findings, including drug resistance, of children with TB in Istanbul, Turkey.
Erkan Çakır, Ela Erdem Eralp, Nagihan Özlü, Engin Seber, Serap Gençer, Zeki Kılıçaslan   +5 more
openalex   +3 more sources

Biocide-Resistant Escherichia coli ST540 Co-Harboring ESBL, dfrA14 Confers QnrS-Dependent Plasmid-Mediated Quinolone Resistance

Antibiotics, 2022
Emerging sequence types of pathogenic bacteria have a dual ability to acquire resistance islands/determinants, and remain renitent towards disinfection practices; therefore, they are considered “critical risk factors” that contribute significantly to the
Srinivasan Vijaya Bharathi, Govindan Rajamohan   +1 more
doaj   +1 more source

Phenotypic Characterization and Heterogeneity among Modern Clinical Isolates of Acinetobacter baumannii

Microbiology Spectrum, 2023
Acinetobacter baumannii is an opportunistic pathogenic bacterium prioritized by WHO and CDC because of its increasing antibiotic resistance. Heterogeneity among strains represents the hallmark of A. baumannii bacteria.
Adam Valcek, Chantal Philippe, Clémence Whiteway, Etienne Robino, Kristina Nesporova, Mona Bové, Tom Coenye, Tim De Pooter, Wouter De Coster, Mojca Strazisar, Charles Van der Henst   +10 more
doaj   +1 more source

The Integration of Proteomics and Metabolomics Data Paving the Way for a Better Understanding of the Mechanisms Underlying Microbial Acquired Drug Resistance

Frontiers in Medicine, 2022
Due to an increase in the overuse of antimicrobials and accelerated incidence of drug resistant pathogens, antimicrobial resistance has become a global health threat.
Suereta Fortuin, N. Soares
semanticscholar   +1 more source

Antimicrobial Activity of a Repurposed Harmine-Derived Compound on Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates

Frontiers in Cellular and Infection Microbiology, 2022
ObjectivesThe spread of antibiotic resistant bacteria is an important threat for human health. Acinetobacter baumannii bacteria impose such a major issue, as multidrug- to pandrug-resistant strains have been isolated, rendering some infections ...
Anke Breine, Anke Breine, Mégane Van Gysel, Mathias Elsocht, Clémence Whiteway, Clémence Whiteway, Chantal Philippe, Théo Quinet, Théo Quinet, Adam Valcek, Adam Valcek, Johan Wouters, Steven Ballet, Charles Van der Henst, Charles Van der Henst   +14 more
doaj   +1 more source