Results 21 to 30 of about 4,488,653 (302)

Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]

open access: yes, 2012
The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
Sylke Müller   +39 more
core   +5 more sources

Antimicrobial resistance and genomic characterization of Salmonella enterica isolates from chicken meat

open access: yesFrontiers in Microbiology, 2023
This study investigated genotypic and phenotypic antimicrobial resistance profiles, phylogenic relatedness, plasmid and virulence composition of 39 Salmonella enterica strains isolated from chicken meat samples using whole genome sequencing (WGS ...
Khaloud O. Alzahrani   +17 more
doaj   +1 more source

Quorum-Sensing Regulation of Antimicrobial Resistance in Bacteria

open access: yesMicroorganisms, 2020
Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome and is related to cell density. The high-density colony population can generate a sufficient number of small molecule signals, activate a variety of downstream ...
Xihong Zhao, Zixuan Yu, Tian Ding
doaj   +1 more source

From environment to clinic: the role of pesticides in antimicrobial resistance

open access: yesRevista Panamericana de Salud Pública, 2020
Antimicrobial resistance (AMR) in pathogens has been associated mainly with excessive use of antibiotics. Most studies of resistance have focused on clinical pathogens; however, microorganisms are exposed to numerous anthropogenic substances. Few studies
Jeadran N. Malagón-Rojas   +2 more
doaj   +1 more source

VIM-1, VIM-2, and GES-5 Carbapenemases Among Pseudomonas aeruginosa Isolates at a Tertiary Hospital in Istanbul, Turkey. [PDF]

open access: yes, 2017
Worldwide increase in carbapenem resistance and transferable carbapenemases are significant challenges in treatment of Pseudomonas aeruginosa infections. In this study, investigation of carbapenemase production in carbapenem-resistant P.
Otlu, Barış   +4 more
core   +1 more source

Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems

open access: yesPharmaceutics, 2022
Antibiotic resistance has become a threat to microbial therapies nowadays. The conventional approaches possess several limitations to combat microbial infections.
Mohammad Imran   +13 more
doaj   +1 more source

Overview on Bacterial Resistance and Nanoparticles to Overcome Bacterial Resistance [PDF]

open access: yesJournal of Advanced Pharmacy Research, 2021
Microbial infections have been the leading cause of death throughout history. This was changed when antibiotics were discovered, causing an increase in life expectancy from 48 years to 72 years. However, this golden era might end very soon. Bacteria have
Yasmin Abo-zeid   +4 more
doaj   +1 more source

Inulin Can Alleviate Metabolism Disorders in ob/ob Mice by Partially Restoring Leptin-related Pathways Mediated by Gut Microbiota

open access: yesGenomics, Proteomics & Bioinformatics, 2019
Inulin has been used as a prebiotic to alleviate glucose and lipid metabolism disorders in mice and humans by modulating the gut microbiota. However, the mechanism underlying the alleviation of metabolic disorders by inulin through interactions between ...
Xiaofeng Song   +11 more
doaj   +1 more source

Multimodal Role of Amino Acids in Microbial Control and Drug Development

open access: yesAntibiotics, 2020
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms including those in the microbial world. They are utilised as nutrients and control many biological functions in microorganisms such as cell division, cell wall formation,
Muhammad Idrees   +3 more
doaj   +1 more source

Drug resistance with monitored adherence [PDF]

open access: yes, 2013
Drug resistance can be defined as the failure of a drug to exert its expected effect on pharmacological biomarkers and is caused by pharmacogenetic, cellular or clinical factors.
Walter, Philipp Niklaus
core   +1 more source

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