Results 21 to 30 of about 203,774 (257)

Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems

Pharmaceutics, 2022
Antibiotic resistance has become a threat to microbial therapies nowadays. The conventional approaches possess several limitations to combat microbial infections.
Mohammad Imran, Saurav Kumar Jha, Nazeer Hasan, Areeba Insaf, Jitendra Shrestha, Jesus Shrestha, Hari Prasad Devkota, Salman Khan, Nisha Panth, Majid Ebrahimi Warkiani, Kamal Dua, Philip M. Hansbro, Keshav Raj Paudel, Yousuf Mohammed   +13 more
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Overview on Bacterial Resistance and Nanoparticles to Overcome Bacterial Resistance [PDF]

Journal of Advanced Pharmacy Research, 2021
Microbial infections have been the leading cause of death throughout history. This was changed when antibiotics were discovered, causing an increase in life expectancy from 48 years to 72 years. However, this golden era might end very soon. Bacteria have
Yasmin Abo-zeid, Amr Amer, Boushra El-Houssieny, Marwa Mahmoud, Wedad Sakran   +4 more
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Inulin Can Alleviate Metabolism Disorders in ob/ob Mice by Partially Restoring Leptin-related Pathways Mediated by Gut Microbiota

Genomics, Proteomics & Bioinformatics, 2019
Inulin has been used as a prebiotic to alleviate glucose and lipid metabolism disorders in mice and humans by modulating the gut microbiota. However, the mechanism underlying the alleviation of metabolic disorders by inulin through interactions between ...
Xiaofeng Song, Liang Zhong, Na Lyu, Fei Liu, Boxing Li, Yanan Hao, Yong Xue, Jing Li, Yuqing Feng, Yue Ma, Yongfei Hu, Baoli Zhu   +11 more
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Multimodal Role of Amino Acids in Microbial Control and Drug Development

Antibiotics, 2020
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms including those in the microbial world. They are utilised as nutrients and control many biological functions in microorganisms such as cell division, cell wall formation,
Muhammad Idrees, Afzal R. Mohammad, Nazira Karodia, Ayesha Rahman   +3 more
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State of Knowledge on the Acquisition, Diversity, Interspecies Attribution and Spread of Antimicrobial Resistance between Humans, Animals and the Environment: A Systematic Review

Antibiotics, 2022
Resistance to antibiotics is considered one of the most urgent global public health concerns. It has considerable impacts on health and the economy, being responsible for the failure to treat infectious diseases, higher morbidity and mortality rates, and
Hélène Meier, Keira Spinner, Lisa Crump, Esther Kuenzli, Gertraud Schuepbach, Jakob Zinsstag   +5 more
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Antimicrobial profile of Acinetobacter baumannii at a tertiary hospital in Honduras: a cross-sectional analysis

Revista Panamericana de Salud Pública, 2020
Acinetobacter baumannii is considered to be a worldwide threat to public health due to its high antimicrobial resistance rates and the severe infections it can cause. Little is known about this pathogen’s resistance in Central America.
Julio Cesar Zuniga-Moya, Clerk Annette Caballero, Mariela Loucel-Linares, Mayra Jazmin Benitez, Edoardo Zambrano-Garcia, Lidice Vanesa Fajardo, Julissa Stephanie Paz, Suyapa A Bejarano, Emilio Barrueto Saavedra, Luis Enrique Romero   +9 more
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Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens

Frontiers in Pharmacology, 2021
Antibiotic resistance or microbial drug resistance is emerging as a serious threat to human healthcare globally, and the multidrug-resistant (MDR) strains are imposing major hurdles to the progression of drug discovery programs.
Tushar Khare, Tushar Khare, Uttpal Anand, Abhijit Dey, Yehuda G. Assaraf, Zhe-Sheng Chen, Zhijun Liu, Vinay Kumar, Vinay Kumar   +8 more
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Biological properties of the major causes factors of purulently inflammatory diseases of surgical patients in Zaporizhzhia Clinical Hospital of Emergency and Critical Care Medicine

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The problem of antibiotic resistance of purulent-inflammatory diseases pathogens that arise in patients during treatment in surgery units is urgent and requires a thorough knowledge of the spectrum of circulating strains of microorganisms and changes in ...
N. M. Polishchuck, D. L. Kyryk, I. Ye. Yurchuk, O. M. Filippova, T. M. Lischenko, S. V. Yehorova   +5 more
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Pharmacokinetic-pharmacodynamic integration of shikimic acid in broilers: An indirect effect modeling approach

Poultry Science
Shikimic acid (SA), a natural polyhydroxy cyclic organic acid, possesses significant anti-inflammatory and antioxidant activities; however, its pharmacokinetic (PK) profile and pharmacodynamic (PD) relationship in poultry remain poorly characterized ...
Yue Shen, Kaibin Mo, Hui Zhao, Yicheng Zhang, Xianhui Huang   +4 more
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Modeling microbial drug-resistance: from mathematics to pharmacoeconomics

Фармакоэкономика, 2018
Complicated intra-abdominal infection (IAI) requires increased health care expenditures and additional resources to compensate for an ineffective starting therapy.Aim. To select the economically optimal algorithm for using antimicrobial agents (AMA) that
Yu. M. Gomon, M. A. Arepyeva, Yu. E. Balykina, A. S. Kolbin, A. A. Kurylev, M. A. Proskurin, S. V. Sidorenko   +6 more
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