Effective elimination of Staphylococcal contamination from hospital surfaces by a bacteriophage-probiotic sanitation strategy: a monocentric study. [PDF]
, 2019 Persistent contamination of hospital surfaces and antimicrobial resistance (AMR) are recognized major causes of healthcare-associated infections (HAI). We recently showed that a probiotic-based sanitation (PCHS) can stably decrease surface pathogens and ...
BISI, Matteo +6 more
core +1 more source
Improved Network Performance via Antagonism: From Synthetic Rescues to Multi-drug Combinations [PDF]
, 2010 Recent research shows that a faulty or sub-optimally operating metabolic network can often be rescued by the targeted removal of enzyme-coding genes--the exact opposite of what traditional gene therapy would suggest.
Adilson E. Motter +58 more
core +3 more sources
A reservoir of 'historical' antibiotic resistance genes in remote pristine Antarctic soils [PDF]
, 2018 Background: Soil bacteria naturally produce antibiotics as a competitive mechanism, with a concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic resistance mechanisms.
Bezuidt, Oliver KI +5 more
core +2 more sources
Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study. [PDF]
, 2019 Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST).
Aller, SD +20 more
core +4 more sources
Engineered Biosensors for Diagnosing Multidrug Resistance in Microbial and Malignant Cells
Biosensors, 2023 To curtail pathogens or tumors, antimicrobial or antineoplastic drugs have been developed. These drugs target microbial/cancer growth and survival, thereby improving the host’s health.
Niharika G. Jha +5 more
semanticscholar +1 more source
The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome. [PDF]
, 2016 Many human skin diseases, such as seborrheic dermatitis, potentially occur due to the over-growth of fungi. It remains a challenge to develop fungicides with a lower risk of generating resistant fungi and non-specifically killing commensal microbes.
Barshop, Bruce A +15 more
core +1 more source
Altered Microbial Composition of Drug-Sensitive and Drug-Resistant TB Patients Compared with Healthy Volunteers [PDF]
Microorganisms, 2021 Mycobacterium tuberculosis infection has three discernible outcomes: active tuberculosis, latent tuberculosis, or clearance of the bacterium. The outcome of the infection depends on the interaction of the bacterium, the immune system, and the microbiome of the host.
Fernanda Valdez-Palomares +4 more
openaire +4 more sources
Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]
, 2018 This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau +3 more
core +2 more sources
Anti-microbial Use in Animals: How to Assess the Trade-offs [PDF]
, 2015 Antimicrobials are widely used in preventive and curative medicine in animals. Benefits from curative use are clear – it allows sick animals to be healthy with a gain in human welfare.
Acar J. F. +12 more
core +1 more source