Evolution of a microbial nitrilase gene family: a comparative and environmental genomics study [PDF]
Abstract Background Completed genomes and environmental genomic sequences are bringing a significant contribution to understanding the evolution of gene families, microbial metabolism and community eco-physiology. Here, we used comparative genomics and phylogenetic analyses in conjunction with enzymatic data to probe ...
Eads Jonathan R +2 more
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Evolution of genome fragility enables microbial division of labor [PDF]
Abstract Division of labor can evolve when social groups benefit from the functional specialization of its members. Recently, a novel means of coordinating division of labor was found in the antibiotic-producing bacterium Streptomyces coelicolor , where functionally specialized ...
Colizzi, Enrico Sandro +4 more
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Microsatellites in Pursuit of Microbial Genome Evolution [PDF]
Microsatellites or short sequence repeats are widespread genetic markers which are hypermutable 1-6 bp long short nucleotide motifs. Significantly, their applications in genetics are extensive due to their ceaseless mutational degree, widespread length variations and hypermutability skills.
Saeed, Abdullah F. +2 more
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Microbial genomic trait evolution is dominated by frequent and rare pulsed evolution [PDF]
Abstract On the macroevolutionary timescale, does trait evolution proceed gradually or by rapid bursts (pulses) separated by prolonged periods of stasis or slow evolution? Although studies have shown pulsed evolution is prevalent in animals, our knowledge about the tempo and mode of evolution across the tree of life is very limited ...
Yingnan Gao, Martin Wu
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Analyzing microbial evolution through gene and genome phylogenies
A bstract Microbiome scientists critically need modern tools to explore and analyze microbial evolution. Often this involves studying the evolution of microbial genomes as a whole. However, different genes in a single genome can be subject to different evolutionary
Sarah Teichman +2 more
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Symbiosis in the microbial world: from ecology to genome evolution [PDF]
ABSTRACT The concept of symbiosis – defined in 1879 by de Bary as ‘the living together of unlike organisms’ – has a rich and convoluted history in biology. In part, because it questioned the concept of the individual, symbiosis fell largely outside mainstream science and has traditionally received less attention than other research ...
Jean-Baptiste Raina +5 more
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Genomes of the T4-related bacteriophages as windows on microbial genome evolution [PDF]
AbstractThe T4-related bacteriophages are a group of bacterial viruses that share morphological similarities and genetic homologies with the well-studiedEscherichia coliphage T4, but that diverge from T4 and each other by a number of genetically determined characteristics including the bacterial hosts they infect, the sizes of their linear double ...
Miller Eric S +4 more
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Development of a genome-targeting mutator for the adaptive evolution of microbial cells [PDF]
Abstract Methods that can randomly introduce mutations in the microbial genome have been used for classical genetic screening and, more recently, the evolutionary engineering of microbial cells. However, most methods rely on either cell-damaging agents or disruptive mutations of genes that are involved in accurate DNA replication, of ...
Ga-eul Eom, Hyunbin Lee, Seokhee Kim
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Structure and evolution of gene regulatory networks in microbial genomes [PDF]
With the availability of genome sequences for hundreds of microbial genomes, it has become possible to address several questions from a comparative perspective to understand the structure and function of regulatory systems, at least in model organisms.
Sarath Chandra, Janga, J, Collado-Vides
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Microbial genome evolution: sources of variability
Comparative genome analyses of close relatives have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. The genomes of free-living bacteria often carry phages and repetitive sequences that mediate genomic rearrangements in contrast to the small
Alex, Mira +2 more
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