Results 21 to 30 of about 3,295,358 (263)

Comparing the Influence of Assembly Processes Governing Bacterial Community Succession Based on DNA and RNA Data

Microorganisms, 2020
Quantifying which assembly processes structure microbiomes can assist prediction, manipulation, and engineering of community outcomes. However, the relative importance of these processes might depend on whether DNA or RNA are used, as they differ in ...
Xiu Jia, Francisco Dini-Andreote, Joana Falcão Salles   +2 more
doaj   +1 more source

Impact of meltwater flow intensity on the spatiotemporal heterogeneity of microbial mats in the McMurdo Dry Valleys, Antarctica

ISME Communications, 2023
The meltwater streams of the McMurdo Dry Valleys are hot spots of biological diversity in the climate-sensitive polar desert landscape. Microbial mats, largely comprised of cyanobacteria, dominate the streams which flow for a brief window of time (~10 ...
A. Zoumplis, B. Kolody, D. Kaul, H. Zheng, P. Venepally, D. M. McKnight, C. Takacs-Vesbach, A. DeVries, A. E. Allen   +8 more
doaj   +1 more source

Measuring Clonal Evolution in Cancer with Genomics. [PDF]

, 2019
Cancers originate from somatic cells in the human body that have accumulated genetic alterations. These mutations modify the phenotype of the cells, allowing them to escape the homeostatic regulation that maintains normal cell number.
Graham, TA, Sottoriva, A, Williams, MJ
core   +1 more source

Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics [version 3; referees: 1 approved, 2 approved with reservations]

F1000Research, 2017
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for ...
Jasper J. Koehorst, Edoardo Saccenti, Peter J. Schaap, Vitor A. P. Martins dos Santos, Maria Suarez-Diez   +4 more
doaj   +1 more source

Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics [version 1; referees: 1 approved, 2 approved with reservations]

F1000Research, 2016
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for ...
Jasper J. Koehorst, Edoardo Saccenti, Peter J. Schaap, Vitor A. P. Martins dos Santos, Maria Suarez-Diez   +4 more
doaj   +1 more source

PanACoTA: a modular tool for massive microbial comparative genomics

, 2021
International audienceThe study of the gene repertoires of microbial species, their pangenomes, has become a key part of microbial evolution and functional genomics.
Rocha, Eduardo, P. C., Perrin, Amandine
core   +1 more source

High efficiency generalized transduction in Escherichia coli O157:H7 [v1; ref status: indexed, http://f1000r.es/8f]

F1000Research, 2013
Genetic manipulation in enterohemorrhagic E. coli O157:H7 is currently restricted to recombineering, a method that utilizes the recombination system of bacteriophage lambda, to introduce gene replacements and base changes inter alia into the genome ...
Martin G Marinus, Anthony R Poteete
doaj   +1 more source

Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling [PDF]

, 2008
Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E. Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY.
Flaschel, Erwin, Vijayendran, Chandran, Friehs, Karl, Niehaus, Karsten, Barsch, Aiko, Becker, Anke   +5 more
core   +1 more source

NG-Tax, a highly accurate and validated pipeline for analysis of 16S rRNA amplicons from complex biomes [version 2; referees: 2 approved, 1 approved with reservations, 1 not approved]

F1000Research, 2018
Background: Massive high-throughput sequencing of short, hypervariable segments of the 16S ribosomal RNA (rRNA) gene has transformed the methodological landscape describing microbial diversity within and across complex biomes.
Javier Ramiro-Garcia, Gerben D. A. Hermes, Christos Giatsis, Detmer Sipkema, Erwin G. Zoetendal, Peter J. Schaap, Hauke Smidt   +6 more
doaj   +1 more source

Cluster analysis of Plasmodium RNA-seq time-course data identifies stage-specific co-regulated biological processes and regulatory elements [version 1; referees: 1 approved, 2 approved with reservations]

F1000Research, 2016
In this study, we interpreted RNA-seq time-course data of three developmental stages of Plasmodium species by clustering genes based on similarities in their expression profile without prior knowledge of the gene function.
Efejiro Ashano, Itunuoluwa Isewon, Jelili Oyelade, Ezekiel Adebiyi   +3 more
doaj   +1 more source