Results 21 to 30 of about 39,725 (303)

Environmental shaping of codon usage and functional adaptation across microbial communities. [PDF]

open access: yes, 2013
Microbial communities represent the largest portion of the Earth's biomass. Metagenomics projects use high-throughput sequencing to survey these communities and shed light on genetic capabilities that enable microbes to inhabit every corner of the ...
Roller, Masa   +4 more
core   +1 more source

Microbial genomics amidst the Arctic crisis [PDF]

open access: yes, 2020
The Arctic is warming – fast. Microbes in the Arctic play pivotal roles in feedbacks that magnify the impacts of Arctic change. Understanding the genome evolution, diversity and dynamics of Arctic microbes can provide insights relevant for both ...
Edwards, Arwyn   +6 more
core   +1 more source

A culture-independent approach to unravel uncultured bacteria and functional genes in a complex microbial community [PDF]

open access: yes, 2012
Most microorganisms in nature are uncultured with unknown functionality. Sequence-based metagenomics alone answers 'who/what are there?' but not 'what are they doing and who is doing it and how?'.
Zhou, Q.   +47 more
core   +1 more source

PanACoTA: a modular tool for massive microbial comparative genomics

open access: yes, 2021
International audienceThe study of the gene repertoires of microbial species, their pangenomes, has become a key part of microbial evolution and functional genomics.
Rocha, Eduardo, P. C., Perrin, Amandine
core   +1 more source

Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics [version 3; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2017
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for ...
Jasper J. Koehorst   +4 more
doaj   +1 more source

Evolution of Microbial Genomes: Sequence Acquisition and Loss

open access: yesMolecular Biology and Evolution, 2002
We present models describing the acquisition and deletion of novel sequences in populations of microorganisms. We infer that most novel sequences are neutral. Thus, sequence duplications and gene transfer between organisms sharing the same environment are rarely expected to generate adaptive functions.
Otto G, Berg, C G, Kurland
openaire   +2 more sources

Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2016
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for ...
Jasper J. Koehorst   +4 more
doaj   +1 more source

Comparing the Influence of Assembly Processes Governing Bacterial Community Succession Based on DNA and RNA Data

open access: yesMicroorganisms, 2020
Quantifying which assembly processes structure microbiomes can assist prediction, manipulation, and engineering of community outcomes. However, the relative importance of these processes might depend on whether DNA or RNA are used, as they differ in ...
Xiu Jia   +2 more
doaj   +1 more source

Dispersal-competition tradeoff in microbiomes in the quest for land colonization

open access: yesScientific Reports, 2018
Ancestor microbes started colonizing inland habitats approximately 2.7 to 3.5 billion years ago. With some exceptions, the key physiological adaptations of microbiomes associated with marine-to-land transitions have remained elusive.
Francisco Dini-Andreote   +3 more
doaj   +1 more source

Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics [version 2; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2016
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for ...
Jasper J. Koehorst   +4 more
doaj   +1 more source

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