Results 81 to 90 of about 39,725 (303)

Bayesian prediction of microbial oxygen requirement [v1; ref status: indexed, http://f1000r.es/1m6]

F1000Research, 2013
Background: Prediction of the optimal habitat conditions for a given bacterium, based on genome sequence alone would be of value for scientific as well as industrial purposes. One example of such a habitat adaptation is the requirement for oxygen.
Dan B. Jensen, David W. Ussery
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Neutral Theory, Microbial Practice: Challenges in Bacterial Population Genetics

, 2018
International audienceI detail four major open problems in microbial population genetics with direct implications to the study of molecular evolution: the lack of neutral polymorphism, the modeling of promiscuous genetic exchanges, the genetics of ill ...
Eduardo P C Rocha, Rocha, Eduardo, P C, Rocha, Eduardo,   +2 more
core   +1 more source

Whole-genome comparison of two Campylobacter jejuni isolates of the same sequence type reveals multiple loci of different ancestral lineage [PDF]

, 2011
Campylobacter jejuni ST-474 is the most important human enteric pathogen in New Zealand, and yet this genotype is rarely found elsewhere in the world. Insight into the evolution of this organism was gained by a whole genome comparison of two ST-474, flaA
Fearnhead, Paul, Biggs, Patrick, Biggs Patrick J., Philip E. Carter, Besser Thomas E., Carter, Philip, Kwan Errol, Patrick J. Biggs, Hotter Grant, Cookson Adrian, Besser, Thomas, Philip E Carter, Kwan, Errol, Mohan Vathsala, Paul Fearnhead, Julie Collins-Emerson, French Nigel P., Mohan, Vathsala, Errol Kwan, Thomas E. Besser, Nigel P French, Hotter, Grant, Grant Hotter, Fearnhead Paul, Collins-Emerson, Julie, Adrian Cookson, Collins-Emerson Julie, Carter Philip E., French, Nigel, Vathsala Mohan, Cookson, Adrian, Thomas E Besser, Patrick J Biggs, Nigel P. French   +33 more
core   +1 more source

Functional characterization of Candida albicans Hos2 histone deacetylase [v2; ref status: indexed, http://f1000r.es/3i2]

F1000Research, 2014
Candida albicans is a mucosal commensal organism capable of causing superficial (oral and vaginal thrush) infections in immune normal hosts, but is a major pathogen causing systemic and mucosal infections in immunocompromised individuals.
G Karthikeyan, Maneesh Paul-Satyaseela, Nachiappan Dhatchana Moorthy, Radha Gopalaswamy, Shridhar Narayanan   +4 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source

EDGAR: a software framework for the comparative analysis of prokaryotic genomes

, 2009
Blom J, Albaum S, Doppmeier D, et al. EDGAR: a software framework for the comparative analysis of prokaryotic genomes. BMC Bioinformatics. 2009;10(1): 154.Background:The introduction of next generation sequencing approaches has caused a rapid increase in
Blom, Jochen, Albaum, Stefan ; https://orcid.org/, Jochen Blom, Martha Zakrzewski, Goesmann, Alexander ; https://orcid.org/, Alfred Puhler, Pühler, Alfred ; https://orcid.org/, Zakrzewski, Martha, Doppmeier, Daniel, Vorhölter, Frank-Jörg, Stefan P Albaum, Daniel Doppmeier, Frank-Jorg Vorholter, Alexander Goesmann   +13 more
core   +1 more source

Clonal yet Different: Understanding the Causes of Genomic Heterogeneity in Microbial Species and Impacts on Public Health

mSystems, 2019
Why are members of a microbial species not the same? They may be clonal, but microbial populations are often composed of multiple cocirculating lineages distinguished by large phenotypic and genetic differences.
Cheryl P. Andam
doaj   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source

Evolution of Catabolic Pathways: Genomic Insights into Microbial s -Triazine Metabolism [PDF]

Journal of Bacteriology, 2007
In recent years, studies on the catabolism of organonitrogen compounds have accelerated due to the recognition that these compounds are widespread and significant environmentally. Nitrogen is the second most abundant macronutrient in cellular organisms, where it is found in major macromolecules (
N, Shapir, E F, Mongodin, M J, Sadowsky, S C, Daugherty, K E, Nelson, L P, Wackett   +5 more
openaire   +2 more sources