Results 71 to 80 of about 3,295,358 (263)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

EDGAR: a software framework for the comparative analysis of prokaryotic genomes [PDF]

, 2009
Blom J, Albaum S, Doppmeier D, et al. EDGAR: a software framework for the comparative analysis of prokaryotic genomes. BMC Bioinformatics. 2009;10(1): 154.Background:The introduction of next generation sequencing approaches has caused a rapid increase in
Blom, Jochen, Albaum, Stefan ; https://orcid.org/, Jochen Blom, Martha Zakrzewski, Goesmann, Alexander ; https://orcid.org/, Alfred Puhler, Pühler, Alfred ; https://orcid.org/, Zakrzewski, Martha, Doppmeier, Daniel, Vorhölter, Frank-Jörg, Stefan P Albaum, Daniel Doppmeier, Frank-Jorg Vorholter, Alexander Goesmann   +13 more
core   +1 more source

Clonal yet Different: Understanding the Causes of Genomic Heterogeneity in Microbial Species and Impacts on Public Health

mSystems, 2019
Why are members of a microbial species not the same? They may be clonal, but microbial populations are often composed of multiple cocirculating lineages distinguished by large phenotypic and genetic differences.
Cheryl P. Andam
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Seeing the forest for the genes: using metagenomics to infer the aggregated traits of microbial communities [PDF]

, 2014
Most environments harbor large numbers of microbial taxa with ecologies that remain poorly described and characterizing the functional capabilities of whole communities remains a key challenge in microbial ecology.
Daniel eLaughlin, Fierer, Noah, Laughlin, Daniel C., Noah Fierer, Noah eFierer, Albert eBarberan, Daniel C. Laughlin, Barberán, Albert, Albert Barberán   +8 more
core   +1 more source

Salinity Gradient Controls Microbial Community Structure and Assembly in Coastal Solar Salterns

, 2022
Salinity acts as a critical environmental filter on microbial communities in natural systems, negatively affecting microbial diversity. However, how salinity affects microbial community assembly remains unclear. This study used Wendeng multi-pond saltern
Dashuai Mu, Qiyun Liang, Xiaoqun Wang, Guanjun Chen, Zhaozhong Du, Zongjun Du, Tianran Song   +6 more
core   +1 more source

Bayesian prediction of microbial oxygen requirement [v1; ref status: indexed, http://f1000r.es/1m6]

F1000Research, 2013
Background: Prediction of the optimal habitat conditions for a given bacterium, based on genome sequence alone would be of value for scientific as well as industrial purposes. One example of such a habitat adaptation is the requirement for oxygen.
Dan B. Jensen, David W. Ussery
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Single virus genomics: a new tool for virus discovery.

PLoS ONE, 2011
Whole genome amplification and sequencing of single microbial cells has significantly influenced genomics and microbial ecology by facilitating direct recovery of reference genome data.
Lisa Zeigler Allen, Thomas Ishoey, Mark A Novotny, Jeffrey S McLean, Roger S Lasken, Shannon J Williamson   +5 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source