Results 111 to 120 of about 112,228 (309)

Chemical markers for rumen methanogens and methanogenesis [PDF]

open access: yes, 2013
Peer ...
Bull, I D   +5 more
core   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

Conversion of biomass to microbial lipids for biofuels

open access: yes, 2017
Conversion of biomass to microbial lipids for ...
赵宗保
core  

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

open access: yesAdvanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral   +7 more
wiley   +1 more source

Decoding nitrogen depletion–induced lipid accumulation in Aurantiochytrium sp. YHPM1 through integrated proteomic and transcriptomic analyses

open access: yesBMC Microbiology
Docosahexaenoic acid (DHA) is a high-value omega-3 polyunsaturated fatty acid (PUFA) with critical roles in human health and nutrition, and Aurantiochytrium species have emerged as promising microbial cell factories for sustainable and scalable DHA ...
Shuxian Pang   +2 more
doaj   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

open access: yesAdvanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu   +10 more
wiley   +1 more source

Kog1 Represses Lipid Accumulation in Mucor circinelloides: A Transcriptomic Analysis Across Nitrogen Conditions

open access: yesJournal of Fungi
Oleaginous microorganisms usually accumulate large amounts of lipids under nitrogen limitation and in a carbon-abundant environment. However, how cells sense changes in nitrogen and carbon levels in the culture medium remains a research hotspot. Previous
Zhen Wang   +4 more
doaj   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

open access: yesAdvanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai   +8 more
wiley   +1 more source

Unveiling the pharmacological promise of Tamarix chinensis Lour: An integrative review of phytochemical constituents, therapeutic potentials, and mechanistic pathways

open access: yesPharmacological Research - Modern Chinese Medicine
Introduction: Tamarix chinensis Lour (TCL) is a known arid plant belonging to the family Tamaricaceae, widely distributed near the Yellow River Delta, northeastern Shandong Province of China.
Muhammad Tariq Saeed   +10 more
doaj   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

open access: yesAdvanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao   +10 more
wiley   +1 more source

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