Results 171 to 180 of about 233,379 (308)

An ultra‐processed food‐based cafeteria diet induces obesity, metabolic dysfunction, and tissue‐specific gene dysregulation in C57BL/6 mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This schematic figure illustrates the experimental design and key findings of the study. Forty male C57BL/6 mice were assigned to either a standard diet control group or a cafeteria diet (CAFD) group for 16 weeks. CAFD induces obesity, insulin resistance (HOMA‐IR), hepatic steatosis, and dysregulation of a number of genes in visceral and subcutaneous ...
Guilherme Coutinho Kullmann Duarte   +9 more
wiley   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma   +2 more
wiley   +1 more source

Lipidomic and Metagenomic Profiling of Chinese Female Emerging Adults With Oily Scalp. [PDF]

open access: yesJ Cosmet Dermatol
Yang F   +7 more
europepmc   +1 more source

Radioactive Springs and Archaeal Life in Deep Groundwater Systems. [PDF]

open access: yesMicrob Ecol
Eckertová T   +3 more
europepmc   +1 more source

Lipid Metabolism and Obesity in Early Life: Drivers of Chronic Lung Disease From Development to Adulthood. [PDF]

open access: yesMol Nutr Food Res
Selle J   +8 more
europepmc   +1 more source

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