Results 1 to 10 of about 4,447,704 (298)
IUCrJ, 2020 Wag31, or DivIVA, is an essential protein and a drug target in the human pathogen Mycobacterium tuberculosis that self-assembles at the negatively curved membrane surface to form a higher-order structural scaffold, maintains rod-shaped cellular ...
Komal Choukate, Barnali Chaudhuri
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The WxxxE proteins in microbial pathogenesis
Critical Reviews in Microbiology, 2022 Effector proteins secreted by pathogens modulate various host cellular processes and help in bacterial pathogenesis. Some of these proteins, injected by enteric pathogens via Type Three Secretion System (T3SS) were grouped together based on a conserved signature motif (WxxxE) present in them.
Sajan Chandrangadhan Achi +4 more
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Inorganics, 2020 [Fe]-hydrogenase (Hmd) catalyzes the reversible heterolytic cleavage of H2, and hydride transfer to methenyl-tetrahydromethanopterin (methenyl-H4MPT+).
Gangfeng Huang +3 more
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Microbial Protein-tyrosine Kinases [PDF]
Journal of Biological Chemistry, 2014 Microbial ester kinases identified in the past 3 decades came as a surprise, as protein phosphorylation on Ser, Thr, and Tyr amino acids was thought to be unique to eukaryotes. Current analysis of available microbial genomes reveals that "eukaryote-like" protein kinases are prevalent in prokaryotes and can converge in the same signaling pathway with ...
Joseph D, Chao +2 more
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Scientific Reports, 2021 Snake envenomation is a severe problem in Sri Lanka (SL) and Indian polyvalent antivenom (PAV) is mostly used for treating snakebite albeit due to geographical variation in venom composition, Indian PAV shows poor efficacy in neutralizing the lethality ...
Aparup Patra +5 more
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Heliyon, 2023 Despite their popularity, plant-based food gel systems (GS) sometimes have suboptimal texture compared to animal-based products. Therefore, 4 commercial plant proteins (from mung bean, pea, potato and soybean) and 2 commercial plant fats (sunflower oil ...
Quinten Masijn +5 more
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Microbial Phospholipid Synthesis as a Marker for Microbial Protein Synthesis in the Rumen [PDF]
Applied Microbiology, 1973 Phosphate uptake into intracellular inorganic phosphorus and cellular phospholipids and the relationship between cell growth and phospholipid synthesis were studied with suspensions of washed ruminal bacteria in vitro with 33 P-phosphorus.
H F, Bucholtz, W G, Bergen
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Artificial Cells, Nanomedicine, and Biotechnology, 2022 Epidermal growth factor receptor (EGFR) is the primary target for the treatment of colorectal cancer, the third most diagnosed cancer worldwide. In recent years, regulatory changes have facilitated the approval of biosimilars aimed to bring more access ...
Jitender Nandal +6 more
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Structure-Guided Designing and Evaluation of Peptides Targeting Bacterial Transcription
Frontiers in Bioengineering and Biotechnology, 2020 The mycobacterial RNA polymerase (RNAP) is an essential and validated drug target for developing antibacterial drugs. The β-subunit of Mycobacterium tuberculosis (Mtb) RNAP (RpoB) interacts with an essential and global transcription factor, CarD, and ...
Gundeep Kaur +4 more
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Genome sequencing and annotation of Amycolatopsis azurea DSM 43854T
Genomics Data, 2014 We report the 9.2 Mb genome of the azureomycin A and B antibiotic producing strain Amycolatopsis azurea isolated from a Japanese soil sample. The draft genome of strain DSM 43854T consists of 9,223,451 bp with a G + C content of 69.0% and the genome ...
Indu Khatri +2 more
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