Results 21 to 30 of about 547,231 (309)

MPIDB: the microbial protein interaction database [PDF]

Bioinformatics, 2008
Abstract Summary: The microbial protein interaction database (MPIDB) aims to collect and provide all known physical microbial interactions. Currently, 22 530 experimentally determined interactions among proteins of 191 bacterial species/strains can be browsed and downloaded.
Johannes Goll, Seesandra V. Rajagopala, Shen C. Shiau, Hank Wu, Brian T. Lamb, Peter Uetz   +5 more
openaire   +3 more sources

Genome sequencing and annotation of Acinetobacter haemolyticus strain MTCC 9819T

Genomics Data, 2014
The genus Acinetobacter consists of 31 validly published species ubiquitously distributed in nature and primarily associated with nosocomial infection. We report the 3.4 Mb genome of Acinetobacter haemolyticus strain MTCC 9819T.
Indu Khatri, Nitin Kumar Singh, Srikrishna Subramanian, Shanmugam Mayilraj   +3 more
doaj   +1 more source

A Novel Therapeutic Formulation for the Improved Treatment of Indian Red Scorpion (Mesobuthus tamulus) Venom-Induced Toxicity-Tested in Caenorhabditis elegans and Rodent Models

Toxins, 2023
Indian Red Scorpion (Mesobuthus tamulus) stings are a neglected public health problem in tropical and sub-tropical countries, including India. The drawbacks of conventional therapies using commercial anti-scorpion antivenom (ASA) and α1-adrenoreceptor ...
Bhabana Das, Dev Madhubala, Saurov Mahanta, Aparup Patra, Upasana Puzari, Mojibur R. Khan, Ashis K. Mukherjee   +6 more
doaj   +1 more source

Genome sequencing and annotation of Acinetobacter guillouiae strain MSP 4-18

Genomics Data, 2014
The genus Acinetobacter consists of 31 validly published species ubiquitously distributed in nature and primarily associated with nosocomial infection. We report the 4.8 Mb genome of Acinetobacter guillouiae MSP 4-18, isolated from a mangrove soil sample
Nitin Kumar Singh, Indu Khatri, Srikrishna Subramanian, Shanmugam Mayilraj   +3 more
doaj   +1 more source

Structure Elucidation and Biochemical Characterization of Environmentally Relevant Novel Extradiol Dioxygenases Discovered by a Functional Metagenomics Approach

mSystems, 2019
The release of synthetic chemical pollutants in the environment is posing serious health risks. Enzymes, including oxygenases, play a crucial role in xenobiotic degradation. In the present study, we employed a functional metagenomics approach to overcome
Chandni Sidhu, Vipul Solanki, Anil Kumar Pinnaka, Krishan Gopal Thakur   +3 more
doaj   +3 more sources

Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype

Communications Biology, 2023
Cellular senescence, a state of irreversible cell-cycle arrest caused by a variety of cellular stresses, is critically involved in age-related tissue dysfunction in various organs. However, the features of cells in the central nervous system that undergo
Tatsuyuki Matsudaira, Sosuke Nakano, Yusuke Konishi, Shimpei Kawamoto, Ken Uemura, Tamae Kondo, Koki Sakurai, Takaaki Ozawa, Takatoshi Hikida, Okiru Komine, Koji Yamanaka, Yuki Fujita, Toshihide Yamashita, Tomonori Matsumoto, Eiji Hara   +14 more
doaj   +1 more source

Recombinant protein expression in microbial systems [PDF]

Frontiers in Microbiology, 2014
With the advent of recombinant DNA technology, expressing heterologous proteins in microorganisms rapidly became the method of choice for their production at laboratory and industrial scale. Bacteria, yeasts and other hosts can be grown to high biomass levels efficiently and inexpensively.
Rosano, German Leandro, Ceccarelli, Eduardo Augusto   +1 more
openaire   +5 more sources

Biochemical and Taxonomic Characterization of Novel Haloarchaeal Strains and Purification of the Recombinant Halotolerant α-Amylase Discovered in the Isolate

Frontiers in Microbiology, 2020
Haloarchaea are salt-loving archaea and potential source of industrially relevant halotolerant enzymes. In the present study, three reddish-pink, extremely halophilic archaeal strains, namely wsp1 (wsp-water sample Pondicherry), wsp3, and wsp4, were ...
Dipesh Kumar Verma, Gunjan Vasudeva, Chandni Sidhu, Anil K. Pinnaka, Senthil E. Prasad, Krishan Gopal Thakur   +5 more
doaj   +1 more source

A novel thermostable alkaline histamine oxidase from Glutamicibacter sp. N1A3101, induced by histamine and its analogue betahistine

AMB Express, 2020
Biogenic amines (BAs) are low molecular weight organic bases formed by natural amino acids decarboxylation and trigger an array of toxicological effects in humans and animals.
Hossein Sadeghi, Sareh Arjmand, Seyed Omid Ranaei Siadat, Jamshid Fooladi, Gholamhossein Ebrahimipour   +4 more
doaj   +1 more source

Structural basis for the biosynthesis of lovastatin

Nature Communications, 2021
Biosynthesis of the statin precursor lovastatin depends on the LovB–LovC megasynthase complex. Here, the authors present cryoEM structures of LovB–LovC and core LovB, providing structural insights into the catalytic cycle underlying lovastatin production.
Jialiang Wang, Jingdan Liang, Lu Chen, Wei Zhang, Liangliang Kong, Chao Peng, Chen Su, Yi Tang, Zixin Deng, Zhijun Wang   +9 more
doaj   +1 more source