Results 81 to 90 of about 641,669 (159)

Gate-keeper of ion transport—a highly conserved helix-3 tryptophan in a channelrhodopsin chimera, C1C2/ChRWR

open access: yesBiophysics and Physicobiology, 2020
Microbial rhodopsin is a large family of membrane proteins having seven transmembrane helices (TM1-7) with an all-trans retinal (ATR) chromophore that is covalently bound to Lys in the TM7. The Trp residue in the middle of TM3, which is homologous to W86
Yujiro Nagasaka   +6 more
doaj   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

open access: yesCell Proliferation, Volume 59, Issue 6, June 2026.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao   +6 more
wiley   +1 more source

Hydrostatic pressure spectroscopy reveals the adaptation of microbial rhodopsins to high-pressure environment

open access: yesScientific Reports
Microbial rhodopsins are light-driven membrane proteins that convert photon energy into biological functions via photocycles initiated by retinal chromophore isomerization. Although their structural and functional properties under ambient conditions have
Tomoyuki Hamachi   +7 more
doaj   +1 more source

The Elusive Fraction of Marine Plankton Diversity: Size, Abundance and Taxonomic Composition of 0.2 μm‐Filterable Prokaryotes Across Three Contrasting Coastal Environments

open access: yesMolecular Ecology, Volume 35, Issue 12, June 2026.
ABSTRACT The existence of prokaryotes escaping filtration through 0.2‐μm filters has been known for decades. Such ‘filterable’ prokaryotes (hereafter ‘FP’) might include true ultra‐small groups (i.e., ultramicrobacteria), but also cells that miniaturize temporally as a physiological strategy to persist under unfavourable conditions, representing a ...
Clara Ruiz‐González   +6 more
wiley   +1 more source

MicRhoDE: a curated database for the analysis of microbial rhodopsin diversity and evolution

open access: yes, 2015
International audienceMicrobial rhodopsins are a diverse group of photoactive transmembrane proteins found in all three domains of life and in viruses.
Brillet-Guéguen, Loraine   +4 more
core   +1 more source

Beyond red/far‐red sensing: phytochrome perception of the marine light field by microalgae

open access: yesNew Phytologist, Volume 250, Issue 5, Page 2837-2844, June 2026.
Summary Phytochromes (PHYs) are a major group of photoreceptors, described as red and far‐red light sensors in land plants. Recent genomic and metagenomic explorations have revealed the presence of PHYs also in various eukaryotic microalgae originating from distinct endosymbiotic events.
Carole Duchêne   +2 more
wiley   +1 more source

Rhodopsin-Like Ionic Gate Fabricated with Graphene Oxide and Isomeric DNA Switch for Efficient Photocontrol of Ion Transport

open access: yes, 2019
Rhodopsin, composed of opsin and isomeric retinal, acts as the primary photoreceptor by converting light into electric signals. Inspired by rhodopsin, we have fabricated a light-regulated ionic gate on the basis of the design of a graphene oxide (GO ...
Tao Gao (1424974)   +17 more
core   +1 more source

Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior

open access: yes, 2022
Over the past 15 years, optogenetic methods have revolutionized neuroscientific and cell biological research, also in the nematode Caenorhabditis elegans.
Gottschalk, A.   +9 more
core   +1 more source

Advantages of human opsins in optogenetic visual restoration

open access: yesFrontiers in Neuroscience
Optogenetic vision restoration has progressed from proof-of-concept to early clinical testing, yet most programmes rely on microbial channels that demand high irradiance and offer limited adaptation.
Mihai Teodor Bica   +2 more
doaj   +1 more source

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