Results 61 to 70 of about 641,669 (159)

Biological Systems as Physical Data Processors: Evolution as a Case of Embodied Computing

BioEssays, Volume 48, Issue 10, October 2026.
Embodied biological computing is process through which biological systems gravitate toward attractors in a solution space through a thermodynamically favored process of information capture. Applications in biotechnology, in particular metabolic engineering are numerous.
Víctor de Lorenzo
wiley   +1 more source

Heliorhodopsin Helps Photolyase to Enhance the DNA Repair Capacity

Microbiology Spectrum, 2022
Light quality is a significant factor for living organisms that have photosensory systems, such as rhodopsin, a seven alpha-helical transmembrane protein with the retinal chromophore.
Jin-gon Shim, Shin-Gyu Cho, Se-Hwan Kim, Kimleng Chuon, Seanghun Meas, Ahreum Choi, Kwang-Hwan Jung   +6 more
doaj   +1 more source

Dual‐Laser Laser‐Induced Liquid Bead Ion Desorption Mass Spectrometry: A New Approach for Adjustable Softness and Higher Sensitivity

ChemPhysChem, Volume 27, Issue 14, 29 July 2026.
Native protein complexes often require gentle ionization to preserve weak interactions, yet higher ion yield typically goes hand in hand with increased in‐source dissociation. Our dual‐laser LILBID approach decouples ion production from dissociation by using two independently tunable pulses, enabling sample‐specific soft conditions and expanding access
Niko Popovic, Jonathan Schulte, Anne Mayer, Clemens Glaubitz, Nina Morgner   +4 more
wiley   +1 more source

The Origins and Evolution of an Early Microbial Rhodopsin Protein

, 2021
The advent of cellular organisms took place sometime between the start of prebiotic chemosynthesis on Earth and the evolution of the last universal common ancestor. Cellularity is now a fundamental organizational principle shared by all life on Earth and
Sephus, Cathryn Dawn
core   +1 more source

Proton-pumping photoreceptor controls expression of ABC transporter by regulating transcription factor through light

Communications Biology
Light is a significant factor for living organisms with photosystems, like microbial rhodopsin—a retinal protein that functions as an ion pump, channel, and sensory transduction.
Jin-gon Shim, Kimleng Chuon, Ji‐Hyun Kim, Sang-ji Lee, Myung-chul Song, Shin-Gyu Cho, Chenda Hour, Kwang-Hwan Jung   +7 more
doaj   +1 more source

Gut Microbiota‐Derived Bacterial Extracellular Vesicles in COVID‐19: Their Signature and Immunological Impact

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
This study demonstrated that the secretion of bacterial extracellular vesicles (BEVs) changes during COVID‐19‐induced gut‐bacterial dysbiosis, and these alterations in BEV profiles influence the immune cell cytokine response, persisting even after clinical remission.
Aya Ishizaka, Michiko Koga, Tomoya Hayashi, Ken J Ishii, Hiroyuki Yamamoto, Hiroshi Yotsuyanagi, Taketoshi Mizutani   +6 more
wiley   +1 more source

The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation [PDF]

, 2002
Mutations in the photopigment rhodopsin are the major cause of autosomal dominant retinitis pigmentosa. The majority of mutations in rhodopsin lead to misfolding of the protein.
Munro, PMG, Cheetham, ME, Saliba, RS, Luthert, PJ   +3 more
core  

Mimicking Microbial Rhodopsin Isomerization in a Single Crystal [PDF]

Journal of the American Chemical Society, 2018
Bacteriorhodopsin represents the simplest, and possibly most abundant, phototropic system requiring only a retinal-bound transmembrane protein to convert photons of light to an energy-generating proton gradient. The creation and interrogation of a microbial rhodopsin mimic, based on an orthogonal protein system, would illuminate the design elements ...
Alireza Ghanbarpour, Muath Nairat, Meisam Nosrati, Elizabeth M. Santos, Chrysoula Vasileiou, Marcos Dantus, Babak Borhan, James H. Geiger   +7 more
openaire   +2 more sources

Red-shifting mutation of light-driven sodium-pump rhodopsin

Nature Communications, 2019
Microbial rhodopsins are photoreceptive and widely used in optogenetics for which they should preferable function with longer-wavelength light. Here, authors achieve a 40-nm red-shift in the absorption wavelength of a sodium-pump rhodopsin (KR2) by ...
Keiichi Inoue, María del Carmen Marín, Sahoko Tomida, Ryoko Nakamura, Yuta Nakajima, Massimo Olivucci, Hideki Kandori   +6 more
doaj   +1 more source

Crystal Structure of the N112A Mutant of the Light-Driven Sodium Pump KR2

Crystals, 2020
The light-driven sodium pump KR2, found in 2013 in the marine bacteria Krokinobacter eikastus, serves as a model protein for the studies of the sodium-pumping microbial rhodopsins (NaRs). KR2 possesses a unique NDQ (N112, D116, and Q123) set of the amino
Nina Maliar, Kirill Kovalev, Christian Baeken, Taras Balandin, Roman Astashkin, Maksim Rulev, Alexey Alekseev, Nikolay Ilyinsky, Andrey Rogachev, Vladimir Chupin, Dmitry Dolgikh, Mikhail Kirpichnikov, Valentin Gordeliy   +12 more
doaj   +1 more source