Results 91 to 100 of about 691,309 (371)

Temporal development of the gut microbiome in early childhood from the TEDDY study

Nature, 2018
The development of the microbiome from infancy to childhood is dependent on a range of factors, with microbial–immune crosstalk during this time thought to be involved in the pathobiology of later life diseases1–9 such as persistent islet autoimmunity ...
C. Stewart, N. Ajami, Jacqueline L. O’Brien, D. Hutchinson, Daniel Patrick Smith, M. Wong, M. C. Ross, R. Lloyd, H. Doddapaneni, G. Metcalf, D. Muzny, R. Gibbs, T. Vatanen, C. Huttenhower, R. Xavier, M. Rewers, W. Hagopian, J. Toppari, A. Ziegler, J. She, B. Akolkar, Å. Lernmark, H. Hyoty, Kendra Vehik, J. Krischer, J. Petrosino   +25 more
semanticscholar   +1 more source

3D Printing of Bacteriophage‐Loaded Hydrogels: Development of a Local and Long‐Lasting Delivery System

Advanced Healthcare Materials, EarlyView.
This research investigates the feasibility of 3D‐printing of a bacteriophage‐containing hydrogel made of alginate and methylcellulose. The printed hydrogels steadily release active bacteriophages for up to 35 days which is beneficial to treat implant‐associated infections.
Corina Vater, Gopala Krishna Mannala, Max von Witzleben, Richard Frank Richter, Nike Walter, Michael Gelinsky, Volker Alt, Anja Lode, Markus Rupp   +8 more
wiley   +1 more source

Influence of diet on the gut microbiome and implications for human health

Journal of Translational Medicine, 2017
Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer.
Rasnik K. Singh, H. Chang, Di Yan, Kristina M. Lee, D. Uçmak, Kirsten Wong, M. Abrouk, B. Farahnik, Mio Nakamura, T. Zhu, T. Bhutani, W. Liao   +11 more
semanticscholar   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

Advanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz, Noa Ben David, Adi Gross, Boaz Mizrahi   +3 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Relationship between skin fungal and bacterial microbiomes and skin pH [PDF]

, 2023
Narifumi Akaza, Kazuto Takasaki, Takahiro Matsudaira, Atsuko Usui, Anna Iijima, Shiori Miura, Youichi Yashiro   +6 more
openalex   +1 more source

A unified catalog of 204,938 reference genomes from the human gut microbiome

Nature Biotechnology, 2020
Comprehensive, high-quality reference genomes are required for functional characterization and taxonomic assignment of the human gut microbiota. We present the Unified Human Gastrointestinal Genome (UHGG) collection, comprising 204,938 nonredundant ...
Alexandre Almeida, Stephen Nayfach, M. Boland, F. Strozzi, Martin Beracochea, Z. Shi, K. Pollard, Ekaterina A. Sakharova, Donovan H. Parks, P. Hugenholtz, N. Segata, N. Kyrpides, R. Finn   +12 more
semanticscholar   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis

Nature Communications, 2018
Bacteriophages of the crAssphage family have not yet been isolated, despite being highly abundant in the human gut. Here, Shkoporov et al. isolate in pure culture one of these viruses and show that it infects the human gut symbiont Bacteroides ...
Andrey N. Shkoporov, Ekaterina V. Khokhlova, C. Brian Fitzgerald, Stephen R. Stockdale, Lorraine A. Draper, R. Paul Ross, Colin Hill   +6 more
doaj   +1 more source

Streptococcus thermophilus APC151 strain is suitable for the manufacture of naturally GABA-enriched bioactive yoghurt

Frontiers in Microbiology, 2016
Consumer interest in health-promoting food products is a major driving force for the increasing global demand of functional (probiotic) dairy foods. Yoghurt is considered the ideal medium for delivery of beneficial functional ingredients.
Daniel M. Linares, Daniel M. Linares, Tom F. O'Callaghan, Tom F. O'Callaghan, Paula M. O'Connor, Paula M. O'Connor, R. Paul Ross, Catherine Stanton, Catherine Stanton   +8 more
doaj   +1 more source