Results 111 to 120 of about 404,796 (363)
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
From the moment of birth, the human body plays host to a rich diversity of microbes. Body sites such as the skin, the gut and the mouth support communities of microorganisms (collectively known as the microbiome) that are both numerous and diverse.
Meehan, Conor J.+2 more
openaire +4 more sources
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji+12 more
wiley +1 more source
Influence of diet on the gut microbiome and implications for human health
Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer.
Rasnik K. Singh+11 more
semanticscholar +1 more source
The uncovering of microbes throughout the human body has changed the way health and disease is viewed. The fact that a urinary tract microbiome exists, irrespective of symptomatology, raises questions on what the microbes are doing. The microbial profile–associated bladder cancer compared to healthy controls suggests the organisms may contribute to ...
Dewar, Malcolm+5 more
openaire +4 more sources
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye+16 more
wiley +1 more source
A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model [PDF]
François‐Pierre Martin+15 more
openalex +1 more source
Microbiome yarns: microbiome basis of memory,,, [PDF]
Timmis, Kenneth N.+4 more
openaire +7 more sources
The burden of foodborne disease has large economic and social consequences worldwide. Despite strict regulations, a number of pathogens persist within the food environment, which is greatly contributed to by a build-up of resistance mechanisms and also ...
Lorraine Anne Draper+6 more
doaj +1 more source