Results 111 to 120 of about 404,796 (363)

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

open access: yesAdvanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia   +29 more
wiley   +1 more source

Frailty and the Microbiome

open access: yes, 2015
From the moment of birth, the human body plays host to a rich diversity of microbes. Body sites such as the skin, the gut and the mouth support communities of microorganisms (collectively known as the microbiome) that are both numerous and diverse.
Meehan, Conor J.   +2 more
openaire   +4 more sources

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

open access: yesAdvanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji   +12 more
wiley   +1 more source

Influence of diet on the gut microbiome and implications for human health

open access: yesJournal of Translational Medicine, 2017
Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer.
Rasnik K. Singh   +11 more
semanticscholar   +1 more source

Microbiome

open access: yes, 2018
The uncovering of microbes throughout the human body has changed the way health and disease is viewed. The fact that a urinary tract microbiome exists, irrespective of symptomatology, raises questions on what the microbes are doing. The microbial profile–associated bladder cancer compared to healthy controls suggests the organisms may contribute to ...
Dewar, Malcolm   +5 more
openaire   +4 more sources

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models

open access: yesAdvanced Science, EarlyView.
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye   +16 more
wiley   +1 more source

A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model [PDF]

open access: gold, 2007
François‐Pierre Martin   +15 more
openalex   +1 more source

Microbiome yarns: microbiome basis of memory,,, [PDF]

open access: yesMicrobial Biotechnology, 2017
Timmis, Kenneth N.   +4 more
openaire   +7 more sources

A bioengineered nisin derivative, M21A, in combination with food grade additives eradicates biofilms of Listeria monocytogenes.

open access: yesFrontiers in Microbiology, 2016
The burden of foodborne disease has large economic and social consequences worldwide. Despite strict regulations, a number of pathogens persist within the food environment, which is greatly contributed to by a build-up of resistance mechanisms and also ...
Lorraine Anne Draper   +6 more
doaj   +1 more source

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