Results 31 to 40 of about 387,307 (387)
The microbiome in bronchiectasis [PDF]
European Respiratory Review, 2019 Bronchiectasis is increasing in prevalence worldwide, yet current treatments available are limited to those alleviating symptoms and reducing exacerbations. The pathogenesis of the disease and the inflammatory, infective and molecular drivers of disease progression are not fully understood, making the development of novel treatments challenging ...
Richardson, Hollian +3 more
openaire +5 more sources
Microbiome definition re-visited: old concepts and new challenges
Microbiome, 2020 The field of microbiome research has evolved rapidly over the past few decades and has become a topic of great scientific and public interest. As a result of this rapid growth in interest covering different fields, we are lacking a clear commonly agreed ...
G. Berg +33 more
semanticscholar +1 more source
phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data
PLoS ONE, 2013 Background The analysis of microbial communities through DNA sequencing brings many challenges: the integration of different types of data with methods from ecology, genetics, phylogenetics, multivariate statistics, visualization and testing.
Paul J. McMurdie, S. Holmes
semanticscholar +1 more source
Microbiome, 2019 The National Institutes of Health (NIH) organized a three-day human microbiome research workshop, August 16–18, 2017, to highlight the accomplishments of the 10-year Human Microbiome Project program, the outcomes of the investments made by the 21 NIH ...
The 2017 NIH-wide microbiome workshop writing team
doaj +1 more source
Gut Microbes, 2023 A high-fat (HF) diet reduces resistance to the foodborne pathogen Listeria monocytogenes. We demonstrate that short-term gavage with A. muciniphila increases resistance to oral and systemic L. monocytogenes infection in mice fed a HF diet. A. muciniphila
Jonathan M. Keane +10 more
doaj +1 more source
Genome Biology, 2013 Plant genomes contribute to the structure and function of the plant microbiome, a key determinant of plant health and productivity. High-throughput technologies are revealing interactions between these complex communities and their hosts in unprecedented detail.
Turner, T, James, E, Poole, P
openaire +4 more sources
Is There a Brain Microbiome? [PDF]
Neuroscience Insights, 2021 Numerous studies have identified microbial sequences or epitopes in pathological and non-pathological human brain samples. It has not been resolved if these observations are artifactual, or truly represent population of the brain by microbes. Given the tempting speculation that resident microbes could play a role in the many neuropsychiatric and ...
openaire +4 more sources
Diet rapidly and reproducibly alters the human gut microbiome
Nature, 2013 Long-term dietary intake influences the structure and activity of the trillions of microorganisms residing in the human gut, but it remains unclear how rapidly and reproducibly the human gut microbiome responds to short-term macronutrient change. Here we
Lawrence A. David +12 more
semanticscholar +1 more source
Choice of assembly software has a critical impact on virome characterisation
Microbiome, 2019 Background The viral component of microbial communities plays a vital role in driving bacterial diversity, facilitating nutrient turnover and shaping community composition.
Thomas D. S. Sutton +4 more
doaj +1 more source
Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson’s disease
Communications Biology, 2021 Stockdale et al. assess longitudinal faecal virome changes in a rat model of Parkinson’s Disease (PD) in which either monomeric or preformed fibrils (PFF) of α-synuclein were administered directly into their enteric nervous system.
Stephen R. Stockdale +8 more
doaj +1 more source