Results 31 to 40 of about 510,029 (347)

Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson’s disease

Communications Biology, 2021
Stockdale et al. assess longitudinal faecal virome changes in a rat model of Parkinson’s Disease (PD) in which either monomeric or preformed fibrils (PFF) of α-synuclein were administered directly into their enteric nervous system.
Stephen R. Stockdale, Lorraine A. Draper, Sarah M. O’Donovan, Wiley Barton, Orla O’Sullivan, Laura A. Volpicelli-Daley, Aideen M. Sullivan, Cora O’Neill, Colin Hill   +8 more
doaj   +1 more source

Discordant transmission of bacteria and viruses from mothers to babies at birth [PDF]

, 2019
BACKGROUND: The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood.
Handley, Scott A, Holtz, Lori R, Lim, Efrem S, Maqsood, Rabia, Ndao, I. Malick, Rodgers, Rachel, Rodriguez, Cynthia, Tarr, Phillip I, Warner, Barbara B   +8 more
core   +2 more sources

SaQuant: a real-time PCR assay for quantitative assessment of Staphylococcus aureus

BMC Microbiology, 2021
Background Molecular assays are important tools for pathogen detection but need to be periodically re-evaluated with the discovery of additional genetic diversity that may cause assays to exclude target taxa or include non-target taxa.
Colin Wood, Jason Sahl, Sara Maltinsky, Briana Coyne, Benjamin Russakoff, David Panisello Yagüe, Jolene Bowers, Talima Pearson   +7 more
doaj   +1 more source

Isolation and characterisation of ΦcrAss002, a crAss-like phage from the human gut that infects Bacteroides xylanisolvens

Microbiome, 2021
Background The gut phageome comprises a complex phage community of thousands of individual strains, with a few highly abundant bacteriophages. CrAss-like phages, which infect bacteria of the order Bacteroidales, are the most abundant bacteriophage family
Emma Guerin, Andrey N. Shkoporov, Stephen R. Stockdale, Joan Colom Comas, Ekaterina V. Khokhlova, Adam G. Clooney, Karen M. Daly, Lorraine A. Draper, Niamh Stephens, Dimitri Scholz, R. Paul Ross, Colin Hill   +11 more
doaj   +1 more source

Akkermansia muciniphila reduces susceptibility to Listeria monocytogenes infection in mice fed a high-fat diet

Gut Microbes, 2023
A high-fat (HF) diet reduces resistance to the foodborne pathogen Listeria monocytogenes. We demonstrate that short-term gavage with A. muciniphila increases resistance to oral and systemic L. monocytogenes infection in mice fed a HF diet. A. muciniphila
Jonathan M. Keane, Vanessa Las Heras, Jorge Pinheiro, Jamie A. FitzGerald, María A. Núñez-Sánchez, Cara M. Hueston, Liam O’Mahony, Paul D. Cotter, Colin Hill, Silvia Melgar, Cormac G. M. Gahan   +10 more
doaj   +1 more source

An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors

Gut Microbes, 2023
Conflicting evidence exists on the association between consumption of non-steroidal anti-inflammatory drugs (NSAIDs) and symptomatic worsening of inflammatory bowel disease (IBD).
Raminder Singh, Valerio Rossini, Stephen R. Stockdale, Gonzalo Saiz-Gonzalo, Naomi Hanrahan, Tanya D’ Souza, Adam Clooney, Lorraine A. Draper, Colin Hill, Ken Nally, Fergus Shanahan, Stefan Andersson-Engels, Silvia Melgar   +12 more
doaj   +1 more source

The Human Microbiome [PDF]

Global Advances in Health and Medicine, 2014
In 2011, at the Society for Integrative Oncology's international meeting in Cleveland, Ohio, Francis Collins, PhD, head of the National Institutes of Health, shocked the audience when he asserted that although his work in the human genome was exciting, he was more impressed by the potential represented by the National Institutes of Health's investment ...
David Riley, Gregory A. Plotnikoff
openaire   +3 more sources

Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection

Microbiome, 2019
Background A westernized diet comprising a high caloric intake from animal fats is known to influence the development of pathological inflammatory conditions.
Vanessa Las Heras, Adam G. Clooney, Feargal J. Ryan, Raul Cabrera-Rubio, Pat G. Casey, Cara M. Hueston, Jorge Pinheiro, Justine K. Rudkin, Silvia Melgar, Paul D. Cotter, Colin Hill, Cormac G. M. Gahan   +11 more
doaj   +1 more source

The prodromal microbiome [PDF]

Movement Disorders, 2017
Non peer ...
openaire   +3 more sources

Unlocking the microbiome

eLife, 2023
Individual species of bacteria and yeast present in the food of wild fruit flies work together to provide the nutrients needed for larval growth.
Rosana BR Ferreira, L Caetano M Antunes
openaire   +4 more sources