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The human microbiota is composed of trillions of microbial cells inhabiting the oral cavity, skin, gastrointestinal (GI) tract, airways, and reproductive organs.
Emily M. Borsom+2 more
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A Bayesian Nonparametric Approach for Identifying Differentially Abundant Taxa in Multigroup Microbiome Data with Covariates [PDF]
Scientific studies in the last two decades have established the central role of the microbiome in disease and health. Differential abundance analysis seeks to identify microbial taxa associated with sample groups defined by a factor such as disease subtype, geographical region, or environmental condition.
arxiv
A Bayesian Zero-Inflated Negative Binomial Regression Model for the Integrative Analysis of Microbiome Data [PDF]
Microbiome `omics approaches can reveal intriguing relationships between the human microbiome and certain disease states. Along with the identification of specific bacteria taxa associated with diseases, recent scientific advancements provide mounting evidence that metabolism, genetics and environmental factors can all modulate these microbial effects.
arxiv
From the moment of birth, the human body plays host to a rich diversity of microbes. Body sites such as the skin, the gut and the mouth support communities of microorganisms (collectively known as the microbiome) that are both numerous and diverse.
Meehan, Conor J.+2 more
openaire +4 more sources
Bacteriophages of the crAssphage family have not yet been isolated, despite being highly abundant in the human gut. Here, Shkoporov et al. isolate in pure culture one of these viruses and show that it infects the human gut symbiont Bacteroides ...
Andrey N. Shkoporov+6 more
doaj +1 more source
Background Faecalibacterium prausnitzii is a ubiquitous member of the human gut microbiome, constituting up to 15% of the total bacteria in the human gut. Substantial evidence connects decreased levels of F.
Cormac Brian Fitzgerald+6 more
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The skin microbiome is in a very close mutualistic relationship with skin cells, influencing their physiology and immunology and participating in many dermatological conditions.
Tiziana Ciardiello+4 more
doaj +1 more source
Sparse tree-based clustering of microbiome data to characterize microbiome heterogeneity in pancreatic cancer [PDF]
There is a keen interest in characterizing variation in the microbiome across cancer patients, given increasing evidence of its important role in determining treatment outcomes. Here our goal is to discover subgroups of patients with similar microbiome profiles.
arxiv
Subclinical mastitis is an asymptomatic inflammatory condition that can be difficult to define and diagnose. In the dairy industry, subclinical mastitis is diagnosed by milk somatic cell counts (SCCs) of ≥250,000 cells mL−1.
Angeliki Angelopoulou+9 more
doaj +1 more source
The prevalence of overweight and obesity has reached epidemic proportions globally over the past few decades. The search for new management approaches continues and among them, targeting the gut microbiota can be envisioned. To date, numerous data showed the involvement of the gut microbes in the regulation and control of host metabolism.
Delzenne, Nathalie M., Rodriguez, Julie
openaire +3 more sources