Results 71 to 80 of about 542,693 (329)

What is a hologenomic adaptation? Emergent individuality and inter-identity in multispecies systems [PDF]

, 2020
Contemporary biological research has suggested that some host–microbiome multispecies systems (referred to as “holobionts”) can in certain circumstances evolve as unique biological individual, thus being a unit of selection in evolution.
Arnellos, Austin, Austin, Austin, Bedau, Bigelow, Boogerd, Boorse, Booth, Bordenstein, Bouchard, Bouchard, Bouchard, Bouchard, Bouchard, Bourrat, Brooks, Brucker, Brucker, Brucker, Burke, Campbell, Canciani, Catania, Chalmers, Chandler, Chiu, Chiu, Chong, Clarke, Clarke, Dethlefsen, DiFrisco, Doolittle, Douglas, Dupré, Dupré, Dupré, Dupré, Díaz, Gilbert, Gilbert, Gilbert, Gilbert, Gilbert, Gilbert, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Godfrey-Smith, Grant, Grant, Green, Guay, Hester, Humphreys, Hurst, Hölldobler, Kim, Kim, Kitcher, Koga, Kushmaro, Laplane, Lemanceau, Lewontin, Lidgard, Lloyd, Lloyd, Lloyd, Lloyd, Lloyd, Louca, Lowe, Maynard-Smith, Mayr, Mazel, McCall, McCall, Mendoza, Miller, Miller, Millikan, Mitchell, Moran, Moreno, Mossio, Mossio, Mumford, Nicholson, Nicholson, Nicholson, Okasha, O’Connor, O’Connor, Pepper, Pradeu, Pradeu, Pradeu, Pradeu, Queller, Reshef, Rosenberg, Rosenberg, Rosenberg, Roughgarden, Rudman, Sapp, Sartenaer, Silberstein, Skillings, Sober, Sober, Sober, Stencel, Stencel, Stencel, Suárez, Suárez, Suárez, Suárez, Taxis, Theis, Thompson, Triviño, Triviño, Uhr, van Gulick, Walsh, Waters, Wiggins, Williams, Wilson, Wilson, Wilson, Wilson, Wright, Zilber-Rosenberg   +139 more
core   +2 more sources

The human microbiome [PDF]

Canadian Medical Association Journal, 2015
The human microbiome (glossary in Appendix 1, available at [www.cmaj.ca/lookup/suppl/doi:10.1503/cmaj.141072/-/DC1][1]) comprises hundreds of previously known and newly discovered microbial species living in distinct communities adapted to specific anatomic sites.[1][2] In healthy adults ...
Bryan Coburn, David S. Guttman
openaire   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Foregut microbiome in development of esophageal adenocarcinoma [PDF]

, 2010
Esophageal adenocarcinoma (EA), the type of cancer linked to heartburn due to gastroesophageal reflux diseases (GERD), has increased six fold in the past 30 years. This cannot currently be explained by the usual environmental or by host genetic factors.
Aaron Tenney, Carlos W. Nossa, Daniel Brami, Eoin L. Brodie, Erika Gerz, Fritz Francois, Gary L. Andersen, Indresh K. Singh, Karen E. Nelson, Les Foster, Liying Yang, Manolito Torralba, Mathangi Thiagarajan, Mengling Liu, Michael Poles, Monika Bihan, Morris Traube, Navjeet Singh, Pinak Shah, Shibu Yooseph, Stuart M. Brown, Sukhleen Bedi, Tamasha Parsons, Todd Z. DeSantis, William E. Oberdorf, Yu Chen, Yu-Hui Rogers, Zhiheng Pei   +27 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Evaluation of 16S rDNA-based community profiling for human microbiome research. [PDF]

PLoS ONE, 2012
The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples.
Jumpstart Consortium Human Microbiome Project Data Generation Working Group
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

A synbiotic mixture of selected oligosaccharides and bifidobacteria assists murine gut microbiota restoration following antibiotic challenge

Microbiome, 2023
Background Typically, animal models studying gastrointestinal microbiotas compromised in early life have employed either germ-free animals or mice treated with a cocktail of antibiotics. Such studies intend to mimic scenarios of infants born by caesarean
Emily C. Hoedt, Cara M. Hueston, Nora Cash, Roger S. Bongers, Jonathan M. Keane, Kees van Limpt, Kaouther Ben Amor, Jan Knol, John MacSharry, Douwe van Sinderen   +9 more
doaj   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source