Results 71 to 80 of about 675,129 (379)
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The gut microbiome in social anxiety disorder: evidence of altered composition and function
Translational Psychiatry, 2023 The microbiome-gut-brain axis plays a role in anxiety, the stress response and social development, and is of growing interest in neuropsychiatric conditions.
Mary I. Butler +13 more
doaj +1 more source
The gut microbiome as a modulator of healthy ageing
Nature reviews: Gastroenterology & hepatology, 2022 The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct.
T. Ghosh, F. Shanahan, P. O’Toole
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The microbiome and human cancer
Science, 2021 Separating microbes and cancers The role of microorganisms in causing and sustaining cancers has been in dispute for centuries. Through the lens of gut- and tumor-associated microbes, Sepich-Poore et al. review our current understanding of the microbiota
G. Sepich-Poore +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Evaluation of 16S rDNA-based community profiling for human microbiome research. [PDF]
PLoS ONE, 2012 The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples.
Jumpstart Consortium Human Microbiome Project Data Generation Working Group
doaj +1 more source
mBio, 2021 New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.
Nathan E. Stone +16 more
doaj +1 more source
Microbiome Datasets Are Compositional: And This Is Not Optional
Frontiers in Microbiology, 2017 Datasets collected by high-throughput sequencing (HTS) of 16S rRNA gene amplimers, metagenomes or metatranscriptomes are commonplace and being used to study human disease states, ecological differences between sites, and the built environment.
G. Gloor +3 more
semanticscholar +1 more source
MedZIM: Mediation analysis for Zero-Inflated Mediators with applications to microbiome data
, 2020 The human microbiome can contribute to the pathogenesis of many complex diseases such as cancer and Alzheimer's disease by mediating disease-leading causal pathways.
Christensen, Brock C. +11 more
core +1 more source