Results 11 to 20 of about 574,054 (312)

Microbiota and faecal microbiota transplant [PDF]

Microbiota in Health and Disease, 2021
As the range of disease states associated with the gut microbiome expands – and the mechanistic links between the gut microbiome and host physiology further deepens – so interest also grows in microbiome manipulation as medical therapy. In particular, bolstered by its established role in recurrent C.
Mullish, BH, Alexander, JL, Segal, JP
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Faecal microbiome-based machine learning for multi-class disease diagnosis

Nature Communications, 2022
Here, using fecal metagenomics data of 2,320 individuals, the authors develop a microbiome-based machine learning approach showing high accuracy for multi-class disease diagnosis, highlighting its potential application in improving noninvasive ...
Qi Su, Qin Liu, Raphaela Iris Lau, Jingwan Zhang, Zhilu Xu, Yun Kit Yeoh, Thomas W. H. Leung, Whitney Tang, Lin Zhang, Jessie Q. Y. Liang, Yuk Kam Yau, Jiaying Zheng, Chengyu Liu, Mengjing Zhang, Chun Pan Cheung, Jessica Y. L. Ching, Hein M. Tun, Jun Yu, Francis K. L. Chan, Siew C. Ng   +19 more
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A Microbiota Assimilation [PDF]

Cell Metabolism, 2018
While the gut microbiota's malleability makes it highly responsive to our environment, it also renders it susceptible to rapid selection by factors associated with an industrialized lifestyle. Recently, in Cell, Vangay et al. (2018) have tracked and revealed rapid and profound changes in the gut community of immigrants to one that resembles long-term ...
Justin, Sonnenburg, Erica, Sonnenburg
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Gut microbiome signatures reflect different subtypes of irritable bowel syndrome

Gut Microbes, 2023
Irritable bowel syndrome (IBS) is a heterogeneous condition with multifactorial pathogenesis. We studied deeply phenotyped individuals with microbiota sequencing enrolled in the American Gut Project.
Qi Su, Hein M Tun, Qin Liu, Yun Kit Yeoh, Joyce Wing Yan Mak, Francis KL Chan, Siew C Ng   +6 more
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Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines

Signal Transduction and Targeted Therapy, 2023
The role of gut microbiota in modulating the durability of COVID-19 vaccine immunity is yet to be characterised. In this cohort study, we collected blood and stool samples of 121 BNT162b2 and 40 CoronaVac vaccinees at baseline, 1 month, and 6 months post
Ye Peng, Lin Zhang, Chris K. P. Mok, Jessica Y. L. Ching, Shilin Zhao, Matthew K. L. Wong, Jie Zhu, Chunke Chen, Shilan Wang, Shuai Yan, Biyan Qin, Yingzhi Liu, Xi Zhang, Chun Pun Cheung, Pui Kuan Cheong, Ka Long Ip, Adrian C. H. Fung, Kenneth K. Y. Wong, David S. C. Hui, Francis K. L. Chan, Siew C. Ng, Hein M. Tun   +21 more
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Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle

Genome Biology, 2021
Background Human-to-human transmission of symbiotic, anaerobic bacteria is a fundamental evolutionary adaptation essential for membership of the human gut microbiota.
Hilary P. Browne, Alexandre Almeida, Nitin Kumar, Kevin Vervier, Anne T. Adoum, Elisa Viciani, Nicholas J. R. Dawson, Samuel C. Forster, Claire Cormie, David Goulding, Trevor D. Lawley   +10 more
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Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome

Nature Communications, 2022
Here, Forster et al. compare 1354 cultured commensal strains (540 species) to 45,403 pathogen strains (12 species), identifying 64,188 MGE-mediated antibiotic resistance gene transfer events between the two groups, and show that 15 broad host range MGEs ...
Samuel C. Forster, Junyan Liu, Nitin Kumar, Emily L. Gulliver, Jodee A. Gould, Alejandra Escobar-Zepeda, Tapoka Mkandawire, Lindsay J. Pike, Yan Shao, Mark D. Stares, Hilary P. Browne, B. Anne Neville, Trevor D. Lawley   +12 more
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Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome

Nature Communications, 2022
Here, by performing an integrative multi-omics analysis coupled to clinical features of COVID-19 patients prospectively followed for up to 6 month, the authors identify specific gut microbiome patterns associated with disease severity and development of ...
Qin Liu, Qi Su, Fen Zhang, Hein M. Tun, Joyce Wing Yan Mak, Grace Chung-Yan Lui, Susanna So Shan Ng, Jessica Y. L. Ching, Amy Li, Wenqi Lu, Chenyu Liu, Chun Pan Cheung, David S. C. Hui, Paul K. S. Chan, Francis Ka Leung Chan, Siew C. Ng   +15 more
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Microbiota in sports

Archives of Microbiology, 2022
AbstractThe influence of microbiota on the human body is currently the subject of many studies. The composition of bacteria colonizing the gastrointestinal tract varies depending on genetic make-up, lifestyle, use of antibiotics or the presence of diseases. The diet is also important in the species diversity of the microbiota. This study is an analysis
Katarzyna Mańkowska, Małgorzata Marchelek-Myśliwiec, Piotr Kochan, Danuta Kosik-Bogacka, Tomasz Konopka, Bartłomiej Grygorcewicz, Paulina Roszkowska, Elżbieta Cecerska-Heryć, Aldona Siennicka, Justyna Konopka, Barbara Dołęgowska   +10 more
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Intestinal microbiota in human health and disease: the impact of probiotics [PDF]

, 2011
The complex communities of microorganisms that colonise the human gastrointestinal tract play an important role in human health. The development of culture-independent molecular techniques has provided new insights in the composition and diversity of the
Gerritsen, J., Vos, W.M., de, Ger T. Rijkers, Smidt, H., Jacoline Gerritsen, Rijkers, G.T., Willem M. de Vos, Hauke Smidt   +7 more
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