Results 41 to 50 of about 347,894 (267)

Microbiota, Food, and Health [PDF]

International Journal of Molecular Sciences, 2019
The effects of specific foods, such as products containing probiotics or prebiotics, on human health and the role of intestinal microbiota in this interaction have been a subject of scientific interest for several decades [...]
Kirsi Laitinen, Miguel Gueimonde
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Probiotic potential of Phocaeicola coprocola in modulating learning and memory behaviors in the honeybee model

Frontiers in Microbiology
IntroductionGut microbial therapy has emerged as a prominent research topic for brain function and disorders. The depletion of Phocaeicola coprocola has been reported in various brain-related conditions, suggesting its possible neuroprotective and ...
Mengqi Xu, Mengqi Xu, Xiaohan Zhang, Xiaohan Zhang, Xi Luo, Guanzhou Zhou, Guanzhou Zhou, Nana Zhang, Xiaoyan Chi, Xiaoyan Chi, Rongrong Ren, Lihua Peng, Gang Sun, Yunsheng Yang, Yunsheng Yang   +14 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Microbiota and Autoimmunity [PDF]

Cold Spring Harbor Perspectives in Biology, 2013
The commensal microbiota affects many aspects of mammalian health including control of the immune system to such a extent that a "commensalocentric" view of the maintenance of overall health could be suggested. Autoimmunity is a case of mistaken identity: The immune system reacts to self-tissues and cells as if they were pathogens. Autoimmune reactions
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Siderophore-harboring gut bacteria and fecal siderophore genes for predicting the responsiveness of fecal microbiota transplantation for active ulcerative colitis

Journal of Translational Medicine
Background Predictive markers for fecal microbiota transplantation (FMT) outcomes in patients with active ulcerative colitis (UC) are poorly defined. We aimed to investigate changes in gut microbiota pre- and post-FMT and to assess the potential value in
Jingshuang Yan, Guanzhou Zhou, Rongrong Ren, Xiaohan Zhang, Nana Zhang, Zikai Wang, Lihua Peng, Yunsheng Yang   +7 more
doaj   +1 more source

The Role of Intestinal Fungi in the Pathogenesis and Treatment of Ulcerative Colitis

Microorganisms
Ulcerative colitis (UC) is a chronic inflammatory bowel disease closely associated with dysbiosis of the gut microbiome, encompassing not only bacterial communities but also fungal populations. Despite the growing recognition of the gut microbiome’s role
Yujing Zhang, Lin Wang, Lihua Peng
doaj   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

A novel synbiotic (SCM06) for anxiety and sensory hyperresponsiveness in children with autism spectrum disorder: an open-label pilot study

npj Biofilms and Microbiomes
Anxiety and sensory hyperresponsiveness are common in children with autism spectrum disorder (ASD), but effective treatments are lacking. Targeting the microbiota-gut-brain axis is a promising strategy.
Oscar W. H. Wong, Zhilu Xu, Sandra S. M. Chan, Flora Y. M. Mo, Caroline K. S. Shea, Qi Su, Monica Y. T. Wan, Chun Pan Cheung, Jessica Y. L. Ching, Whitney Tang, Hein M. Tun, Francis K. L. Chan, Siew C. Ng   +12 more
doaj   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source

Cancer and the microbiota [PDF]

Science, 2015
A host’s microbiota may increase, diminish, or have no effect at all on cancer susceptibility. Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host-microbiota interactions with environmental factors in carcinogenesis, and exploiting such knowledge for cancer diagnosis and treatment are areas of intensive interest. This
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