Results 21 to 30 of about 485,986 (267)

Gut Microbiota and NAFLD: Pathogenetic Mechanisms, Microbiota Signatures, and Therapeutic Interventions

, 2021
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Its worldwide prevalence is rapidly increasing and is currently estimated at 24%.
Miloslav Kverka, Tomas Hrncir, Pavlina Kralickova, Lucia Hrncirova, Vladimira Machova, Helena Tlaskalova-Hogenova, Jan Krejsek, Klara Kostovcikova, Robert Hromadka, Eva Trckova   +9 more
core   +1 more source

Characterization of Exosporium Layer Variability of Clostridioides difficile Spores in the Epidemically Relevant Strain R20291

Frontiers in Microbiology, 2020
Clostridioides difficile is a Gram-positive anaerobic intestinal pathogenic bacterium and the causative agent of antibiotic-associated diarrhea. C. difficile spore is a dormant state which acts as a vehicle of transmission and infection. In C.
Marjorie Pizarro-Guajardo, Marjorie Pizarro-Guajardo, Paulina Calderón-Romero, Alba Romero-Rodríguez, Alba Romero-Rodríguez, Daniel Paredes-Sabja, Daniel Paredes-Sabja   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Alteration of Gut Microbiota in Carbapenem-Resistant Enterobacteriaceae Carriers during Fecal Microbiota Transplantation According to Decolonization Periods

, 2021
Fecal microbiota transplantation (FMT) has been suggested as an alternative therapeutic option to decolonize carbapenem-resistant Enterobacteriaceae (CRE).
Ki Tae Suk, Jin-Jae Lee, Heung-Jeong Woo, Bong-Soo Kim, Dongeun Yong, Dong Joon Kim, Seung Soon Lee   +6 more
core   +1 more source

Gut microbiome composition and strain-sharing in multiplex autism spectrum disorder families

Nature Communications
Autism spectrum disorder (ASD) is associated with alteration of gut microbiome, but the influence of familial structure on it remains poorly understood.
Wenqi Lu, Oscar W. H. Wong, Jie Zhu, Sizhe Chen, Hein M. Tun, Yating Wan, Zhilu Xu, Chun Pan Cheung, Jessica Y. L. Ching, Pui Kuan Cheong, Sandra Chan, Samuel Wong, Dorothy Chan, Francis Ka Leung Chan, Qi Su, Siew Chien Ng   +15 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The Gut Microbiota May Affect Personality in Mongolian Gerbils

, 2022
The “gut–microbiota–brain axis” reveals that gut microbiota plays a critical role in the orchestrating behavior of the host. However, the correlation between the host personalities and the gut microbiota is still rarely known.
Lin Gan, Wang, Dehua, Liu, Wei, Dehua Wang, Gan, Lin, Bo, Tingbei, Tingbei Bo, Wei Liu   +7 more
core   +1 more source

Distinct diet-microbiome associations in autism spectrum disorder

Nature Communications
Autism spectrum disorder (ASD) is linked to both altered gut microbiota and unhealthy diets; however, the mechanistic connections remain elusive. In this study, we conducted a systematic analysis of fecal microbiome metagenomic data, paired with granular
Yuqi Wu, Oscar Wong, Sizhe Chen, Yun Wang, Wenqi Lu, Chun Pan Cheung, Jessica Y. L. Ching, Pui Kuan Cheong, Sandra Chan, Patrick Leung, Francis K. L. Chan, Qi Su, Siew C. Ng   +12 more
doaj   +1 more source

Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions

Nature Communications, 2021
Germ-free mosquitoes generated with current methods exhibit developmental deficits. Here, the authors use genetically modified bacteria to allow complete decolonisation at any developmental stage of Aedes aegypti mosquitoes and show that bacteria support
Ottavia Romoli, Johan Claes Schönbeck, Siegfried Hapfelmeier, Mathilde Gendrin   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source